Moffitt Cancer Center researchers have developed a novel reagent that enhances the precision of drug synthesis. This innovative method, published in Nature Communications, introduces a new sulfur fluoride exchange (SuFEx) reagent that allows for highly controlled production of crucial sulfur-based molecules, including sulfinamides, sulfonimidamides and sulfoximines.
A new national study provides the best evidence to date that generous unemployment insurance benefits during the COVID-19 pandemic helped reduce reliance on high-cost credit use. Researchers found that lower-income residents of states with more generous benefits were significantly less likely than those living in less-generous states to take out new credit cards, personal finance loans and payday loans or other alternative financial service offerings.
Students, alumni and faculty from the School of Earth and Sustainability leveraged the power of big data to take another look at the 4.2 ka event—a historic megadrought thought to have Earth-altering effects. What they found in the data pointed to a different conclusion, not only about that event but about how the climate may change in the future.
University Hospitals (UH) Seidman Cancer Center hematologist-oncologist Leland Metheny, MD, is leading the trial. He says in the two years since the foundational pre-clinical work was completed, the team has shown that it’s feasible to manufacture BAFF CAR T-cells for human subjects.
Researchers at Washington University School of Medicine in St. Louis describe the dramatic changes within nerve cells that make regeneration possible. Such findings could inspire the development of new therapies for spinal cord injuries in people.
La actividad coordinada de las células cerebrales, como la de los pájaros que vuelan en formación, nos ayuda a comportarnos de forma inteligente en situaciones nuevas, de acuerdo con un estudio dirigido por investigadores de Cedars-Sinai.
The coordinated activity of brain cells, like birds flying in formation, helps us behave intelligently in new situations, according to a study led by Cedars-Sinai investigators.
A research team – co-led by Penn Nursing – has made a significant breakthrough in understanding the complex neural circuitry underlying reward and addiction by identifying 34 distinct subtypes of medium spiny neurons (MSNs) in the nucleus accumbens (NAc), a key brain region involved in pleasure and motivation. The findings, published in the journal Scientific Reports by Nature, offer insights into the diversity of these neurons and their potential roles in substance use disorders.
A new technique developed at Berkeley Lab will make it much easier for researchers to discover the traits or activities encoded by genes of unknown function in microbes, a key step toward understanding the roles and impact of individual species within the planet’s diverse microbiomes.
An international research team led by the Centre for Microbiology and Environmental Systems Science (CeMESS) at the University of Vienna has discovered that comammox bacteria, first identified by them in 2015, can grow using guanidine, a nitrogen-rich organic compound, as their sole energy and nitrogen source.
In a preliminary study with a small number of humans, rabbits and mice, researchers at Johns Hopkins Children’s Center say they have developed four new regimens that have the potential to treat and save the lives of people with multidrug-resistant (MDR) tuberculous (TB) meningitis.
New research from Memorial Sloan Kettering Cancer Center (MSK) found patients with non-small cell lung cancer brain metastases may benefit from up-front stereotactic radiosurgery; identified a connection between antibiotic use and autoimmune diseases; and uncovered a previously unknown structural role for messenger RNAs in the cytoplasm of cells.
Scientists from Yale University and the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have developed a systematic approach to understanding how energy is lost from the materials that make up qubits. Energy loss inhibits the performance of these quantum computer building blocks, so determining its sources — and adjusting the materials as necessary — can help bring researchers closer to designing quantum computers that could revolutionize several scientific fields.
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have completed the most extensive mapping of healthy breast cells to date. These findings offer an important tool for researchers at IU and beyond to understand how breast cancer develops and the differences in breast tissue among genetic ancestries.
Researchers at UC San Diego have shed new light on how the brain processes and synthesizes information. Findings help solve a longstanding mystery in neuroscience.
Materials science and engineering researchers at the University of Illinois Urbana-Champaign have found that the helical structure shows greatly enhanced conductivity compared to the “random coil” counterparts.
A Korean research team has presented the first universal design principles for solid-state batteries, signaling a paradigm shift in battery design research that previously lacked standard benchmarks. By applying the design principles, a 310Wh/kg-class pouch cell was produced and obtained third-party certification.
New Cleveland Clinic research shows that consuming foods with erythritol, a popular artificial sweetener, increases risk of cardiovascular events such as heart attack and stroke. The findings, from a new intervention study in healthy volunteers, show erythritol made platelets (a type of blood cell) more active, which can raise the risk of blood clots.