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Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS.
description / astdescription / ast
artículu científicu espublizáu en 2011
artículu científicu
description / ukdescription / uk
наукова стаття, опублікована в березні 2011
наукова стаття
Property / main subject
 
Property / main subject: neurotoxicity / rank
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Property / main subject: neurotoxicity / reference
 
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Property / main subject: amyotrophic lateral sclerosis / rank
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Property / main subject: amyotrophic lateral sclerosis / reference
 
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Property / main subject: toxic encephalopathy / rank
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Property / main subject: toxic encephalopathy / reference
 
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Property / cites work: Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo / rank
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Property / cites work: Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo / reference
 
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Property / cites work: TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration / rank
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Property / cites work: TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration / reference
 
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Property / cites work: TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity / rank
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Property / cites work: TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity / reference
 
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Property / cites work: Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis / rank
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Property / cites work: Two German kindreds with familial amyotrophic lateral sclerosis due to TARDBP mutations / rank
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Property / cites work: Two German kindreds with familial amyotrophic lateral sclerosis due to TARDBP mutations / reference
 
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Property / cites work: TDP-43 is a culprit in human neurodegeneration, and not just an innocent bystander / rank
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Property / cites work: A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity / rank
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Property / cites work: TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis / rank
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Property / cites work: TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis / rank
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Property / cites work: TDP-43 A315T mutation in familial motor neuron disease / rank
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Property / cites work: TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor / rank
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Property / cites work: TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis / rank
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Property / cites work: TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis / reference
 
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Property / cites work: Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis / rank
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Property / cites work: TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations / rank
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Property / cites work: TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations / reference
stated in: PubMed Central
reference URL: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098735
retrieved: 16 August 2018
Timestamp+2018-08-16T00:00:00Z
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Property / cites work: Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior / rank
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Property / cites work: Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior / reference
stated in: PubMed Central
reference URL: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098735
retrieved: 16 August 2018
Timestamp+2018-08-16T00:00:00Z
Timezone+00:00
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Property / cites work: TDP-43 neuropathology is similar in sporadic amyotrophic lateral sclerosis with or without TDP-43 mutations. / rank
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stated in: PubMed Central
reference URL: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098735
retrieved: 16 August 2018
Timestamp+2018-08-16T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
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stated in: PubMed Central
reference URL: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098735
retrieved: 16 August 2018
Timestamp+2018-08-16T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
 
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retrieved: 16 August 2018
Timestamp+2018-08-16T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
 
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retrieved: 16 August 2018
Timestamp+2018-08-16T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
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Timestamp+2018-08-16T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
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retrieved: 16 August 2018
Timestamp+2018-08-16T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
 
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retrieved: 16 August 2018
Timestamp+2018-08-16T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
 
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retrieved: 16 August 2018
Timestamp+2018-08-16T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
 
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retrieved: 12 December 2020
Timestamp+2020-12-12T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
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based on heuristic: inferred from PubMed ID database lookup
 

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