Latest revision | Your text |
label / nl | label / nl |
| Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS.
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description / ast | description / ast |
| artículu científicu espublizáu en 2011 | | artículu científicu |
description / uk | description / uk |
| наукова стаття, опублікована в березні 2011 | | наукова стаття |
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Property / main subject: neurotoxicity / rank | |
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Property / main subject: neurotoxicity / reference | |
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Property / main subject: amyotrophic lateral sclerosis / rank | |
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Property / main subject: amyotrophic lateral sclerosis / reference | |
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Property / main subject: toxic encephalopathy / rank | |
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Property / main subject: toxic encephalopathy / reference | |
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Property / cites work: The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism / rank | |
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Property / cites work: The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism / reference | |
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Property / cites work: Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy / rank | |
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Property / cites work: Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy / reference | |
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Property / cites work: Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes / reference | |
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Property / cites work: TDP-43-mediated neuron loss in vivo requires RNA-binding activity / reference | |
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Property / cites work: Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS / reference | |
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Property / cites work: Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS). / reference | |
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Property / cites work: A Drosophila model for TDP-43 proteinopathy / reference | |
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Property / cites work: Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis / reference | |
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Property / cites work: Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo / reference | |
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Property / cites work: TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration / reference | |
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Property / cites work: TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity / reference | |
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Property / cites work: Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6 / rank | |
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Property / cites work: Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6 / reference | |
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Property / cites work: Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis / rank | |
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Property / cites work: Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis / reference | |
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Property / cites work: Two German kindreds with familial amyotrophic lateral sclerosis due to TARDBP mutations / reference | |
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