BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway (Q74046490)

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scientific article published on 01 August 2000

Language	Label	Description	Also known as
English	BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway	scientific article published on 01 August 2000

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10908618%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10908618%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

David M. Holtzman

2

object named as

D M Holtzman

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10908618%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

author name string

B H Han

1

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8 November 2019

publication date

1 August 2000

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8 November 2019

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10908618%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

20

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8 November 2019

15

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8 November 2019

5775-5781

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10908618%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Regulated neurotrophin receptor responsiveness during neuronal migrationand early differentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotransmitter alterations in a model of perinatal hypoxic-ischemic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative metabolism, apoptosis and perinatal brain injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction via the MAP kinases: proceed at your own RSK.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D(2) dopamine receptors induce mitogen-activated protein kinase and cAMP response element-binding protein phosphorylation in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anoxic-ischemic encephalopathy in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular-regulated kinases and phosphatidylinositol 3-kinase are involved in brain-derived neurotrophic factor-mediated survival and neuritogenesis of the neuroblastoma cell line SH-SY5Y.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of nuclear DNA fragmentation following hypoxia-ischemia in the infant rat brain, and transient forebrain ischemia in the adult gerbil

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection from ischemic brain injury by hypoxic preconditioning in the neonatal rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate receptor signaling interplay modulates stress-sensitive mitogen-activated protein kinases and neuronal cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of phosphatidylinositol 3-kinase by brain-derived neurotrophic factor gene transfection in septo-hippocampal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin receptors: a window into neuronal differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased apoptosis in the cingulate sulcus of newborn piglets following transient hypoxia-ischaemia is related to the degree of high energy phosphate depletion during the insult

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The AMPA receptor interacts with and signals through the protein tyrosine kinase Lyn

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: a phenotype indistinguishable from Bax deletion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor expands ocular dominance columns in visual cortex in monocularly deprived and nondeprived kittens but does not in adult cats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for TrkA during maturation of striatal and basal forebrain cholinergic neurons in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in a neonatal rat model of cerebral hypoxia-ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of c-fos and hsp70 mRNA in neonatal rat cerebrocortical slices during NMDA-induced necrosis and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide mediates N-methyl-D-aspartate receptor-induced activation of p21ras

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of immaturity on hypoxic‐ischemic brain damage in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERKI/II regulation by the muscarinic acetylcholine receptors in neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF blocks caspase-3 activation in neonatal hypoxia-ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental biology of cerebral hypoxia-ischemia: relation to perinatal brain damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marked age-dependent neuroprotection by brain-derived neurotrophic factor against neonatal hypoxic-ischemic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA fragmentation indicative of apoptosis following unilateral cerebral hypoxia-ischemia in the neonatal rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines and perinatal brain injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear condensation and fragmentation following cerebral hypoxia-ischemia occurs more frequently in immature than older rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: convergence of estrogen and neurotrophin signaling pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of a single allele of the nerve growth factor gene results in atrophy of basal forebrain cholinergic neurons and memory deficits

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligodendrocytes and their precursors require phosphatidylinositol 3-kinase signaling for survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/10908618

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.20-15-05775.2000

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10908618%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10908618%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10908618%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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