S100 calcium binding protein A9 (Q21102026)

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mammalian protein found in Homo sapiens

p14
calprotectin L1H subunit
calgranulin B
Calgranulin-B
MRP-14
S100 calcium-binding protein A9
migration inhibitory factor-related protein 14
S100A9
protein S100-A9
leukocyte L1 complex heavy chain

Language	Label	Description	Also known as
English	S100 calcium binding protein A9	mammalian protein found in Homo sapiens	p14 calprotectin L1H subunit calgranulin B Calgranulin-B MRP-14 S100 calcium-binding protein A9 migration inhibitory factor-related protein 14 S100A9 protein S100-A9 leukocyte L1 complex heavy chain

Statements

1 reference

13 November 2019

UniProt protein ID

EF-hand domain pair

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P06702

EF-hand domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

S100/CaBP-9k-type, calcium binding, subdomain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EF-Hand 1, calcium-binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

S100/Calbindin-D9k, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

calcium ion binding

determination method or standard

3 references

8 April 2019

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

Related calcium-binding proteins map to the same subregion of chromosome 1q and to an extended region of synteny on mouse chromosome 3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

signal transducer activity

determination method or standard

1 reference

17 October 2017

Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

metal ion binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

antioxidant activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

protein binding

determination method or standard

4 references

8 April 2019

Target-selective protein S-nitrosylation by sequence motif recognition

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

Functional specialization of beta-arrestin interactions revealed by proteomic analysis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

Analysis of the MRP8-MRP14 protein-protein interaction by the two-hybrid system suggests a prominent role of the C-terminal domain of S100 proteins in dimer formation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

A human MAP kinase interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

extracellular exosome

determination method or standard

4 references

17 October 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

17 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

determination method or standard

1 reference

17 October 2017

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

extracellular matrix

determination method or standard

1 reference

17 October 2017

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

extracellular space

determination method or standard

4 references

17 October 2017

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

17 October 2017

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

17 October 2017

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

17 October 2017

Innate immunity proteins and a new truncated form of SPLUNC1 in nasopharyngeal aspirates from infants with respiratory syncytial virus infection

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

determination method or standard

3 references

8 April 2019

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

secretory granule lumen

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

extracellular region

determination method or standard

4 references

17 October 2017

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

17 October 2017

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06702&geneProductId=UniProtKB:P06702

determination method or standard

extracellular region

determination method or standard

4 references

8 April 2019

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

extracellular space

determination method or standard

4 references

8 April 2019

Innate immunity proteins and a new truncated form of SPLUNC1 in nasopharyngeal aspirates from infants with respiratory syncytial virus infection

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

determination method or standard

1 reference

8 April 2019

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

collagen-containing extracellular matrix

determination method or standard

4 references

8 April 2019

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

extracellular exosome

determination method or standard

3 references

8 April 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

biological process

peptidyl-cysteine S-trans-nitrosylation

determination method or standard

1 reference

8 April 2019

Target-selective protein S-nitrosylation by sequence motif recognition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

positive regulation of inflammatory response

determination method or standard

1 reference

8 April 2019

Proinflammatory activities of S100: proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

chemokine production

determination method or standard

1 reference

8 April 2019

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

immune system process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

cellular oxidant detoxification

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

cell-cell signaling

determination method or standard

1 reference

8 April 2019

Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

cytokine production

determination method or standard

1 reference

8 April 2019

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

leukocyte migration involved in inflammatory response

determination method or standard

1 reference

8 April 2019

Proinflammatory activities of S100: proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

neutrophil chemotaxis

determination method or standard

1 reference

8 April 2019

Proinflammatory activities of S100: proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

defense response to fungus

determination method or standard

1 reference

8 April 2019

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

sequestering of zinc ion

determination method or standard

1 reference

8 April 2019

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

neutrophil aggregation

determination method or standard

1 reference

8 April 2019

Proinflammatory activities of S100: proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

positive regulation of cell growth

determination method or standard

1 reference

8 April 2019

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

defense response to bacterium

determination method or standard

1 reference

8 April 2019

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

positive regulation of NF-kappaB transcription factor activity

determination method or standard

1 reference

8 April 2019

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

regulation of inflammatory response

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

activation of cysteine-type endopeptidase activity involved in apoptotic process

determination method or standard

1 reference

8 April 2019

S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

positive regulation of intrinsic apoptotic signaling pathway

determination method or standard

1 reference

8 April 2019

S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

regulation of cytoskeleton organization

determination method or standard

1 reference

8 April 2019

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

apoptotic process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

toll-like receptor signaling pathway

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

antimicrobial humoral response

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

neutrophil degranulation

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

positive regulation of neuron projection development

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06702

determination method or standard

Identifiers

MeSH descriptor ID

subject named as

Calgranulin B

0 references

D12.776.157.125.750.500.200

0 references

D12.776.631.658.750.750

0 references

D23.050.301.562.200

0 references

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000357727

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000357727

PDB structure ID

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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