Junction adhesion molecule 3 (Q21988195)

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mammalian protein found in Mus musculus

JAM-3
junctional adhesion molecule C
junction cell adhesion molecule 3
junction cell adhesion molecule C
Jam3
junctional adhesion molecule 3
JAM-2

Language	Label	Description	Also known as
English	Junction adhesion molecule 3	mammalian protein found in Mus musculus	JAM-3 junctional adhesion molecule C junction cell adhesion molecule 3 junction cell adhesion molecule C Jam3 junctional adhesion molecule 3 JAM-2

Statements

1 reference

25 May 2022

UniProt protein ID

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9D8B7

Immunoglobulin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9D8B7

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Immunoglobulin subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin V-set domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin subtype 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein homodimerization activity

determination method or standard

1 reference

14 February 2019

Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

integrin binding

determination method or standard

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

protein binding

determination method or standard

2 references

14 February 2019

Coxsackievirus and adenovirus receptor (CAR) is expressed in male germ cells and forms a complex with the differentiation factor JAM-C in mouse testis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Loss of partitioning-defective-3/isotype-specific interacting protein (par-3/ASIP) in the elongating spermatid of RA175 (IGSF4A/SynCAM)-deficient mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

protein heterodimerization activity

determination method or standard

1 reference

14 February 2019

Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

integral component of membrane

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

cell-cell junction

determination method or standard

4 references

14 February 2019

JAM-C regulates tight junctions and integrin-mediated cell adhesion and migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-C

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Novel distribution of junctional adhesion molecule-C in the neural retina and retinal pigment epithelium

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

bicellular tight junction

determination method or standard

1 reference

27 February 2018

Novel distribution of junctional adhesion molecule-C in the neural retina and retinal pigment epithelium

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D8B7&geneProductId=UniProtKB:Q9D8B7

determination method or standard

plasma membrane

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

determination method or standard

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

Schmidt-Lanterman incisure

determination method or standard

1 reference

14 February 2019

Tricellulin is expressed in autotypic tight junctions of peripheral myelinating Schwann cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

extracellular region

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

extracellular space

determination method or standard

determination method or standard

1 reference

14 February 2019

The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

bicellular tight junction

determination method or standard

3 references

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D8B7&geneProductId=UniProtKB:Q9D8B7

determination method or standard

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D8B7&geneProductId=UniProtKB:Q9D8B7

determination method or standard

10 September 2018

Novel distribution of junctional adhesion molecule-C in the neural retina and retinal pigment epithelium

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D8B7&geneProductId=UniProtKB:Q9D8B7

determination method or standard

integral component of plasma membrane

determination method or standard

bicellular tight junction

determination method or standard

5 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Novel distribution of junctional adhesion molecule-C in the neural retina and retinal pigment epithelium

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

biological process

neutrophil homeostasis

determination method or standard

1 reference

14 February 2019

Pulmonary dysfunction and impaired granulocyte homeostasis result in poor survival of Jam-C-deficient mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

regulation of neutrophil chemotaxis

determination method or standard

regulation of actin cytoskeleton organization by cell-cell adhesion

determination method or standard

1 reference

14 February 2019

Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-C

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

myeloid progenitor cell differentiation

determination method or standard

1 reference

14 February 2019

Genetic deletion of JAM-C reveals a role in myeloid progenitor generation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

adaptive immune response

determination method or standard

1 reference

14 February 2019

Adaptive immune response in JAM-C-deficient mice: normal initiation but reduced IgG memory

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

axon regeneration

determination method or standard

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

transmission of nerve impulse

determination method or standard

1 reference

14 February 2019

Expression and function of junctional adhesion molecule-C in myelinated peripheral nerves

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

leukocyte migration involved in inflammatory response

determination method or standard

1 reference

14 February 2019

Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

determination method or standard

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

spermatogenesis

determination method or standard

1 reference

10 September 2018

Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-C

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D8B7&geneProductId=UniProtKB:Q9D8B7

determination method or standard

establishment of cell polarity

determination method or standard

1 reference

14 February 2019

JAM-C regulates tight junctions and integrin-mediated cell adhesion and migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

spermatid development

determination method or standard

1 reference

14 February 2019

Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-C

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

determination method or standard

1 reference

14 February 2019

Expression and function of junctional adhesion molecule-C in myelinated peripheral nerves

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

determination method or standard

1 reference

14 February 2019

JAM-C regulates tight junctions and integrin-mediated cell adhesion and migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

determination method or standard

5 references

14 February 2019

The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Adaptive immune response in JAM-C-deficient mice: normal initiation but reduced IgG memory

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

cell differentiation

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D8B7

determination method or standard

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000034472

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000034472

Sitelinks

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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