bleomycin A2 (Q26841044): Difference between revisions

@@ description / nds / description / nds @@
+cheemsch Verbinnen
@@ description / tr / description / tr @@
+kimyasal bileşik
@@ Property / PubChem CID: 5460769 / reference @@
+matched by identifier from: InChIKey
InChIKey: OYVAGSVQBOHSSS-UAPAGMARSA-O
@@ Property / instance of @@
-chemical compound
@@ Property / instance of: chemical compound / rank @@
-Normal rank
@@ Property / instance of: chemical compound / reference @@
-stated in: PubChem
@@ Property / instance of @@
-bleomycins
@@ Property / instance of: bleomycins / rank @@
-Normal rank
@@ Property / instance of @@
-thiazole alkaloid
@@ Property / instance of: thiazole alkaloid / rank @@
-Normal rank
@@ Property / instance of: thiazole alkaloid / reference @@
-inferred from: thiazole alkaloid
@@ Property / chemical formula @@
-C₅₅H₈₄N₁₇O₂₁S₃+
@@ Property / chemical formula: C₅₅H₈₄N₁₇O₂₁S₃+ / rank @@
-Normal rank
@@ Property / chemical formula: C₅₅H₈₄N₁₇O₂₁S₃+ / reference @@
-stated in: PubChem
PubChem CID: 5460769
language of work or name: English
title: bleomycin a2 (English)
retrieved: 21 September 2016Timestamp +2016-09-21T00:00:00Z
Timezone +00:00
Calendar Gregorian
Precision 1 day
Before 0
After 0
-Timestamp
++2016-09-21T00:00:00Z
-Timezone
++00:00
-Calendar
+Gregorian
-Precision
+day
 Before
 After
@@ Property / ChEBI ID: 3139 / reference @@
+matched by identifier from: International Chemical Identifier
InChI: InChI=1S/C55H83N17O21S3/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88)/p+1/t21-,22+,23+,24-,25-,29-,30+,34-,35-,36-,37+,38+,39-,40-,41-,42-,43-,53+,54-/m0/s1
@@ Property / DSSTox substance ID: DTXSID20872327 / reference @@
+matched by identifier from: InChIKey
InChIKey: OYVAGSVQBOHSSS-UAPAGMARSA-O
@@ Property / found in taxon: Streptomyces verticillus / reference @@
+stated in: A mammalian vector carrying the bleomycin N-acetyltransferase gene from bleomycin-producing Streptomyces verticillus as a selective marker
@@ Property / found in taxon: Streptomyces verticillus / reference @@
+stated in: Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide-polyketide antitumor drug bleomycin
@@ Property / found in taxon: Streptomyces verticillus / reference @@
+stated in: Overproduction of the bleomycin-binding proteins from bleomycin-producing Streptomyces verticillus and a methicillin-resistant Staphylococcus aureus in Escherichia coli and their immunological characterisation.
@@ Property / found in taxon: Streptomyces verticillus / reference @@
+stated in: The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase
@@ Property / found in taxon: Streptomyces verticillus / reference @@
+stated in: Production of bleomycin N-acetyltransferase in Escherichia coli and Streptomyces verticillus
@@ Property / found in taxon: Streptomyces verticillus / reference @@
+stated in: Mutation of the N-terminal proline 9 of BLMA from Streptomyces verticillus abolishes the binding affinity for bleomycin.
@@ Property / found in taxon: Streptomyces verticillus / reference @@
+stated in: Negative regulation of bleomycins biosynthesis by ArsR/SmtB family repressor BlmR in Streptomyces verticillus
@@ Property / found in taxon: Streptomyces verticillus / reference @@
+stated in: An oxidation domain in the BlmIII non-ribosomal peptide synthetase probably catalyzing thiazole formation in the biosynthesis of the anti-tumor drug bleomycin in Streptomyces verticillus ATCC15003.
@@ Property / found in taxon: Streptomyces verticillus / reference @@
+stated in: The 1.5 A crystal structure of a bleomycin resistance determinant from bleomycin-producing Streptomyces verticillus
@@ Property / instance of @@
+type of chemical entity
@@ Property / instance of: type of chemical entity / rank @@
+Normal rank
@@ Property / found in taxon @@
+Streptomyces mobaraensis
@@ Property / found in taxon: Streptomyces mobaraensis / rank @@
+Normal rank
@@ Property / found in taxon: Streptomyces mobaraensis / reference @@
+stated in: Genome Mining of Streptomyces mobaraensis DSM40847 as a Bleomycin Producer Providing a Biotechnology Platform To Engineer Designer Bleomycin Analogues.
@@ Property / subclass of @@
+thiazole alkaloid
@@ Property / subclass of: thiazole alkaloid / rank @@
+Normal rank
@@ Property / subclass of @@
+bleomycins
@@ Property / subclass of: bleomycins / rank @@
+Normal rank
@@ Property / UniChem compound ID @@
@@ Property / UniChem compound ID: 329739 / rank @@
+Normal rank
@@ Property / UniChem compound ID: 329739 / reference @@
+stated in: UniChem
@@ Property / chemical formula @@
+C₅₅H₈₄N₁₇O₂₁S₃⁺
@@ Property / chemical formula: C₅₅H₈₄N₁₇O₂₁S₃⁺ / rank @@
+Normal rank
@@ Property / chemical formula: C₅₅H₈₄N₁₇O₂₁S₃⁺ / reference @@
+based on heuristic: inferred from SMILES
@@ Property / Natural Product Atlas ID @@
+NPA020036
@@ Property / Natural Product Atlas ID: NPA020036 / rank @@
+Normal rank
@@ Property / Natural Product Atlas ID: NPA020036 / reference @@
+based on heuristic: inferred from InChIKey
@@ Property / Natural Product Atlas ID: NPA020036 / reference @@
+matched by identifier from: InChIKey
InChIKey: OYVAGSVQBOHSSS-UAPAGMARSA-O
@@ Property / SureChEMBL ID @@
+SCHEMBL134155
@@ Property / SureChEMBL ID: SCHEMBL134155 / rank @@
+Normal rank
@@ Property / SureChEMBL ID: SCHEMBL134155 / reference @@
+based on heuristic: inferred from InChIKey
@@ Property / SureChEMBL ID: SCHEMBL134155 / reference @@
+matched by identifier from: InChIKey
InChIKey: OYVAGSVQBOHSSS-UAPAGMARSA-O

Latest revision as of 00:26, 23 May 2024

chemical compound

bleomycin A₂
bleogin
N1-[3-(Dimethylsulfonio)propyl]bleomycinamide
pingyangmycin A2
zhengguangmycin A2

Language	Label	Description	Also known as
English	bleomycin A2	chemical compound	bleomycin A₂ bleogin N1-[3-(Dimethylsulfonio)propyl]bleomycinamide pingyangmycin A2 zhengguangmycin A2

Statements

instance of

type of chemical entity

0 references

0 references

0 references

1,414.518981±0 dalton

1 reference

language of work or name

English

title

bleomycin a2 (English)

retrieved

21 September 2016

chemical formula

C₅₅H₈₄N₁₇O₂₁S₃⁺

1 reference

based on heuristic

inferred from SMILES

canonical SMILES

CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O

1 reference

language of work or name

English

title

bleomycin a2 (English)

retrieved

21 September 2016

isomeric SMILES

CC1=C(N=C(N=C1N)[C@H](CC(=O)N)NC[C@@H](C(=O)N)N)C(=O)N[C@@H]([C@H](C2=CN=CN2)O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)CO)O)O)O[C@@H]4[C@H]([C@H]([C@@H]([C@H](O4)CO)O)OC(=O)N)O)C(=O)N[C@H](C)[C@H]([C@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O

1 reference

language of work or name

English

title

bleomycin a2 (English)

retrieved

21 September 2016

found in taxon