Structural Characterization of Zinc-deficient Human Superoxide Dismutase and Implications for ALS (Q27648424)

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Language	Label	Description	Also known as
English	Structural Characterization of Zinc-deficient Human Superoxide Dismutase and Implications for ALS	scientific article

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scholarly article

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Structural Characterization of Zinc-deficient Human Superoxide Dismutase and Implications for ALS (English)

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amyotrophic lateral sclerosis

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based on heuristic

inferred from title

Elizabeth D. Getzoff

3

object named as

Elizabeth D Getzoff

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2

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Blaine R Roberts

object named as

Blaine R Roberts

1

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author name string

Dean A Malencik

4

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Sonia R Anderson

5

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Valerie C Bomben

6

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Kathrin R Meyers

7

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P Andrew Karplus

8

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Joseph S Beckman

9

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language of work or name

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publication date

2 November 2007

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Journal of Molecular Biology

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373

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4

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877-90

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Molecular dynamics using atomic-resolution structure reveal structural fluctuations that may lead to polymerization of human Cu Zn superoxide dismutase

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ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization

1 reference

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Solution structure of Apo Cu,Zn superoxide dismutase: role of metal ions in protein folding

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Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS

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The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis

1 reference

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1 reference

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Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase

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Structure and dynamics of copper-free SOD: The protein before binding copper

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Structural changes in a cryo-cooled protein crystal owing to radiation damage

1 reference

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Specific chemical and structural damage to proteins produced by synchrotron radiation

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Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface

1 reference

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Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

1 reference

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20 March 2017

Determination and analysis of the 2 A-structure of copper, zinc superoxide dismutase

1 reference

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20 March 2017

Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase

1 reference

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Structure validation by Calpha geometry: phi,psi and Cbeta deviation

1 reference

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Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Satisfying hydrogen bonding potential in proteins

1 reference

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1 reference

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1 reference

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

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Announcing the worldwide Protein Data Bank

1 reference

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The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis

1 reference

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Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria

1 reference

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Lipid modification of the Cu,Zn superoxide dismutase from Mycobacterium tuberculosis

1 reference

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20 March 2017

Unique features of the sodC-encoded superoxide dismutase from Mycobacterium tuberculosis, a fully functional copper-containing enzyme lacking zinc in the active site

1 reference

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20 March 2017

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

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7 April 2017

Amyotrophic lateral sclerosis

1 reference

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7 April 2017

Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria

1 reference

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29 September 2017

Destabilization of apoprotein is insufficient to explain Cu,Zn-superoxide dismutase-linked ALS pathogenesis.

1 reference

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29 September 2017

Modeling analytical ultracentrifugation experiments with an adaptive space-time finite element solution of the Lamm equation

1 reference

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Aberrantly increased hydrophobicity shared by mutants of Cu,Zn-superoxide dismutase in familial amyotrophic lateral sclerosis.

1 reference

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29 September 2017

When X-rays modify the protein structure: radiation damage at work.

1 reference

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Folding of human superoxide dismutase: disulfide reduction prevents dimerization and produces marginally stable monomers

1 reference

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Mutant copper-zinc superoxide dismutase binds to and destabilizes human low molecular weight neurofilament mRNA.

1 reference

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Dimer destabilization in superoxide dismutase may result in disease-causing properties: structures of motor neuron disease mutants.

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29 September 2017

Aggregation of ALS mutant superoxide dismutase expressed in Escherichia coli

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29 September 2017

Zn(II) metabolism in prokaryotes.

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29 September 2017

Amyotrophic lateral sclerosis: a proposed mechanism

1 reference

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29 September 2017

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

1 reference

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29 September 2017

Structure and mechanism of copper, zinc superoxide dismutase

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29 September 2017

Evolution of CuZn superoxide dismutase and the Greek key beta-barrel structural motif

1 reference

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Thermal denaturation of nucleosomal core particles

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Subunit asymmetry in the three-dimensional structure of a human CuZnSOD mutant found in familial amyotrophic lateral sclerosis

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27 November 2018

Sedimentation velocity analysis of highly heterogeneous systems.

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27 November 2018

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27 November 2018

An intersubunit disulfide bond prevents in vitro aggregation of a superoxide dismutase-1 mutant linked to familial amytrophic lateral sclerosis

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27 November 2018

Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis.

1 reference

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27 November 2018

Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis

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27 November 2018

Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature

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On the Coordination and Oxidation States of the Active-Site Copper Ion in Prokaryotic Cu,Zn Superoxide Dismutases

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Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS

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27 November 2018

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Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

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https://pubmed.ncbi.nlm.nih.gov/17888947

12 December 2020

based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/17888947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/17888947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the cytosolic Cu,Zn superoxide dismutase fromSchistosoma mansoni

1 reference

https://pubmed.ncbi.nlm.nih.gov/17888947

12 December 2020

based on heuristic

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The coupling between disulphide status, metallation and dimer interface strength in Cu/Zn superoxide dismutase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17888947

12 December 2020

based on heuristic

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A characterization of copper/zinc superoxide dismutase mutants at position 124. Zinc-deficient proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17888947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/17888947

12 December 2020

based on heuristic

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A pH-dependent superoxide dismutase activity for zinc-free bovine erythrocuprein. Reexamination of the role of zinc in the holoprotein

1 reference

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

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10.1016/J.JMB.2007.07.043

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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