Generation and evaluation of a large mutational library from the Escherichia coli mechanosensitive channel of large conductance, MscL: implications for channel gating and evolutionary design (Q28188123)

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scientific article (publication date: 6 June 2003)

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English	Generation and evaluation of a large mutational library from the Escherichia coli mechanosensitive channel of large conductance, MscL: implications for channel gating and evolutionary design	scientific article (publication date: 6 June 2003)

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scholarly article

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Generation and evaluation of a large mutational library from the Escherichia coli mechanosensitive channel of large conductance, MscL: implications for channel gating and evolutionary design (English)

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Escherichia coli

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based on heuristic

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Joshua A Maurer

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Joshua A Maurer

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ORCID Public Data File 2021

author name string

Dennis A Dougherty

2

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language of work or name

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publication date

6 June 2003

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Journal of Biological Chemistry

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278

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23

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21076-82

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A large-conductance mechanosensitive channel in E. coli encoded by mscL alone

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https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Mechanosensitive channels of Escherichia coli: the MscL gene, protein, and activities

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https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Mechanosensitive channels in prokaryotes.

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https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Bacterial mechanosensitive channels: integrating physiology, structure and function

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https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Energetic and spatial parameters for gating of the bacterial large conductance mechanosensitive channel, MscL

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https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Estimation of the pore size of the large-conductance mechanosensitive ion channel of Escherichia coli.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Single residue substitutions that change the gating properties of a mechanosensitive channel in Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Mutations in a bacterial mechanosensitive channel change the cellular response to osmotic stress

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https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

One face of a transmembrane helix is crucial in mechanosensitive channel gating

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https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Hydrophilicity of a single residue within MscL correlates with increased channel mechanosensitivity

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https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Crystal structure and mechanism of a calcium-gated potassium channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Structural determinants of MscL gating studied by molecular dynamics simulations

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https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Conformational pathways in the gating of Escherichia coli mechanosensitive channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Molecular dynamics simulations of wild-type and mutant forms of the Mycobacterium tuberculosis MscL channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Structural models of the MscL gating mechanism

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https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

The gating mechanism of the large mechanosensitive channel MscL

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Open channel structure of MscL and the gating mechanism of mechanosensitive channels.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

A high-throughput screen for MscL channel activity and mutational phenotyping

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Molecular dissection of the large mechanosensitive ion channel (MscL) of E. coli: mutants with altered channel gating and pressure sensitivity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Comparing and contrasting Escherichia coli and Mycobacterium tuberculosis mechanosensitive channels (MscL). New gain of function mutations in the loop region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Conducting-state properties of the KcsA potassium channel from molecular and Brownian dynamics simulations.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Gramicidin A channels switch between stretch activation and stretch inactivation depending on bilayer thickness

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Mechanosensitive channels in archaea

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Use of small fluorescent molecules to monitor channel activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Microbial fatty acids and thermal adaptation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Contributions of the different extramembranous domains of the mechanosensitive ion channel MscL to its response to membrane tension.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Electromechanical coupling model of gating the large mechanosensitive ion channel (MscL) of Escherichia coli by mechanical force.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Stretch-activation and stretch-inactivation of Shaker-IR, a voltage-gated K+ channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Membrane stretch accelerates activation and slow inactivation in Shaker channels with S3-S4 linker deletions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Functional design of bacterial mechanosensitive channels. Comparisons and contrasts illuminated by random mutagenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Metabolism of phosphoglycerides in Escherichia coli during growth at 37 °C and during a cold-induced lag phase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302892200

21 January 2018

Effect of growth temperature on the fatty acid composition of Mycobacterium phlei

1 reference

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21 January 2018

Distribution of lipids in cytoplasmic and outer membranes of Escherichia coli K12

1 reference

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21 January 2018

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10.1074/JBC.M302892200

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