Mutation of the androgen receptor causes oncogenic transformation of the prostate (Q33732154)

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7 January 2020

title

Mutation of the androgen receptor causes oncogenic transformation of the prostate (English)

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7 January 2020

4

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7 January 2020

Francesco J DeMayo

6

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7 January 2020

author name string

Guangzhou Han

1

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7 January 2020

Grant Buchanan

2

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7 January 2020

Michael Ittmann

3

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7 January 2020

Xiaoqing Yu

5

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7 January 2020

Wayne Tilley

7

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7 January 2020

Norman M Greenberg

8

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7 January 2020

language of work or name

English

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publication date

18 January 2005

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Proceedings of the National Academy of Sciences of the United States of America

7 January 2020

published in

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7 January 2020

volume

102

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7 January 2020

issue

4

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7 January 2020

page(s)

1151-1156

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Biological control through regulated transcriptional coactivators

7 January 2020

cites work

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Targeting the androgen receptor: improving outcomes for castration-resistant prostate cancer

21 June 2018

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The androgen receptor gene mutations database (ARDB): 2004 update

21 June 2018

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An androgen receptor NH2-terminal conserved motif interacts with the COOH terminus of the Hsp70-interacting protein (CHIP)

21 June 2018

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Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee.

21 June 2018

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Steroid hormones, polypeptide growth factors, hormone refractory prostate cancer, and the neuroendocrine phenotype

21 June 2018

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Molecular determinants of resistance to antiandrogen therapy

21 June 2018

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Immunization against luteinizing hormone-releasing hormone fusion proteins does not decrease prostate cancer in the transgenic adenocarcinoma mouse prostate model

21 June 2018

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Prostate cancer: a dynamic illness with shifting targets

21 June 2018

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The influence of finasteride on the development of prostate cancer

21 June 2018

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Intermittent androgen suppression for prostate cancer: rationale and clinical experience

21 June 2018

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A history of prostate cancer treatment

21 June 2018

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The development of androgen-independent prostate cancer

21 June 2018

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Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone

21 June 2018

1 reference

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HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway.

21 June 2018

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Inhibition of growth and induction of apoptosis by androgens of a variant of LNCaP cell line

21 June 2018

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Hormone status selects for spontaneous somatic androgen receptor variants that demonstrate specific ligand and cofactor dependent activities in autochthonous prostate cancer.

21 June 2018

1 reference

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Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations

21 June 2018

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Two mutations identified in the androgen receptor of the new human prostate cancer cell line MDA PCa 2a.

21 June 2018

1 reference

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Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist

21 June 2018

1 reference

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From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

21 June 2018

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Intermittent complete androgen blockade in metastatic prostate cancer

21 June 2018

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Androgen receptor gene and hormonal therapy failure of prostate cancer

21 June 2018

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Metastatic prostate cancer in a transgenic mouse

21 June 2018

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The rat probasin gene promoter directs hormonally and developmentally regulated expression of a heterologous gene specifically to the prostate in transgenic mice.

21 June 2018

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 June 2018

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Prostate cancer in a transgenic mouse

21 June 2018

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Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor

21 June 2018

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The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens

21 June 2018

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STUDIES ON PROSTATIC CANCER

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0408925102

Conformational analysis of the androgen receptor amino-terminal domain involved in transactivation. Influence of structure-stabilizing solutes and protein-protein interactions

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0408925102

Role of conserved hydrophobic amino acids in androgen receptor AF-1 function

21 January 2018

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Pattern of somatic androgen receptor gene mutations in patients with hormone-refractory prostate cancer

21 January 2018

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A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy

30 October 2018

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Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence

30 October 2018

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12 December 2020

Enforced expression of FGF-7 promotes epithelial hyperplasia whereas a dominant negative FGFR2iiib promotes the emergence of neuroendocrine phenotype in prostate glands of transgenic mice

1 reference

12 December 2020

Collocation of androgen receptor gene mutations in prostate cancer

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12 December 2020

Positional dependence of the effects of negatively charged Glu side chains on the stability of two-stranded α-helical coiled-coils

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12 December 2020

Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer

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12 December 2020

Pathobiology of autochthonous prostate cancer in a pre‐clinical transgenic mouse model

1 reference

12 December 2020

Characterization of the FGF axis and identification of a novel FGFR1iiic isoform during prostate cancer progression in the TRAMP model

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0408925102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15657128%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

0 references

1 reference

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7 January 2020

PubMed publication ID

15657128

1 reference