Modified-chitosan/siRNA nanoparticles downregulate cellular CDX2 expression and cross the gastric mucus barrier (Q35187370)

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scientific article

Language	Label	Description	Also known as
English	Modified-chitosan/siRNA nanoparticles downregulate cellular CDX2 expression and cross the gastric mucus barrier	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Modified-chitosan/siRNA nanoparticles downregulate cellular CDX2 expression and cross the gastric mucus barrier (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

0 references

object named as

Ana Sadio

1

0 references

object named as

Carla Pereira Gomes

4

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object named as

Bruno Pereira

3

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object named as

Raquel Almeida

8

0 references

object named as

Ana Paula Pêgo

7

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Gunnar C Hansson

object named as

Gunnar C Hansson

5

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object named as

Leonor David

6

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author name string

Jenny K Gustafsson

2

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

language of work or name

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publication date

12 June 2014

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

e99449

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

copyright license

Creative Commons Attribution 4.0 International

12 June 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

The gastrointestinal mucus system in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Mucin biopolymers prevent bacterial aggregation by retaining cells in the free-swimming state.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

CDX2 is an amplified lineage-survival oncogene in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy

1 reference

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13 July 2018

Gastric intestinal metaplasia revisited: function and regulation of CDX2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Therapeutic siRNA: principles, challenges, and strategies.

1 reference

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13 July 2018

Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

An ex vivo method for studying mucus formation, properties, and thickness in human colonic biopsies and mouse small and large intestinal explants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

CDX2 autoregulation in human intestinal metaplasia of the stomach: impact on the stability of the phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Chitosanase-based method for RNA isolation from cells transfected with chitosan/siRNA nanocomplexes for real-time RT-PCR in gene silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Chitosan/siRNA nanoparticles biofunctionalize nerve implants and enable neurite outgrowth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Pathophysiology of intestinal metaplasia of the stomach: emphasis on CDX2 regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Insulin-loaded nanoparticles based on N-trimethyl chitosan: in vitro (Caco-2 model) and ex vivo (excised rat jejunum, duodenum, and ileum) evaluation of penetration enhancement properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Chitosan-based formulations for delivery of DNA and siRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Improving chitosan-mediated gene transfer by the introduction of intracellular buffering moieties into the chitosan backbone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Principles of cancer therapy: oncogene and non-oncogene addiction

1 reference

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13 July 2018

Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Trimethyl chitosan and its applications in drug delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

1 reference

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Breaking up the correlation between efficacy and toxicity for nonviral gene delivery

1 reference

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13 July 2018

Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

RNA interference is mediated by 21- and 22-nucleotide RNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055692

13 July 2018

N-trimethyl chitosan chloride as a potential absorption enhancer across mucosal surfaces: in vitro evaluation in intestinal epithelial cells (Caco-2).

1 reference

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Terminal and progenitor lineage-survival oncogenes as cancer markers.

1 reference

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Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells.

1 reference

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Establishment and characterization of two cell lines derived from human diffuse gastric carcinomas xenografted in nude mice.

1 reference

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The adherent gastrointestinal mucus gel layer: thickness and physical state in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/24925340

12 December 2020

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Identifiers

10.1371/JOURNAL.PONE.0099449

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

2014PLoSO...999449S

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

ResearchGate publication ID

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