Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases (Q35548571)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8016110%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

title

Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases (English)

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22 October 2019

4

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22 October 2019

Masahiko Hibi

5

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22 October 2019

David A. Brenner

7

1 reference

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22 October 2019

6

M Karin

1 reference

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22 October 2019

author name string

J K Westwick

1

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22 October 2019

A D Cox

2

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22 October 2019

C J Der

3

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22 October 2019

language of work or name

English

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publication date

1 June 1994

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8016110%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

22 October 2019

published in

1 reference

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22 October 2019

volume

91

1 reference

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22 October 2019

issue

13

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22 October 2019

page(s)

6030-6034

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Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

22 October 2019

cites work

1 reference

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Functional analysis of a growth factor-responsive transcription factor complex

12 July 2018

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Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro

12 July 2018

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Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

12 July 2018

1 reference

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Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

12 July 2018

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Signal transduction via the MAP kinases: proceed at your own RSK.

12 July 2018

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The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

12 July 2018

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Extracellular signals and reversible protein phosphorylation: what to Mek of it all.

12 July 2018

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

12 July 2018

1 reference

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Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

12 July 2018

1 reference

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Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

12 July 2018

1 reference

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Complex formation between RAS and RAF and other protein kinases

12 July 2018

1 reference

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The mitogen-activated protein kinase signal transduction pathway

12 July 2018

1 reference

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Proteins regulating Ras and its relatives

12 July 2018

1 reference

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Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

12 July 2018

1 reference

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The Ras signal transduction pathway

12 July 2018

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

12 July 2018

1 reference

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Definition of the human raf amino-terminal regulatory region by deletion mutagenesis

12 July 2018

1 reference

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Activation of the cellular proto-oncogene product p21Ras by addition of a myristylation signal

12 July 2018

1 reference

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ras-induced neuronal differentiation of PC12 cells: possible involvement of fos and jun

12 July 2018

1 reference

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The GTPase superfamily: a conserved switch for diverse cell functions

12 July 2018

1 reference

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DNA-mediated gene transfer into adult rat hepatocytes in primary culture

12 July 2018

1 reference

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Transcription factors nuclear factor I and Sp1 interact with the murine collagen alpha 1 (I) promoter

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44131

Raf-1 protein kinase is required for growth of induced NIH/3T3 cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44131

The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44131

Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes

12 July 2018

1 reference

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Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

12 July 2018

1 reference

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Phosphorylation of c-jun mediated by MAP kinases.

12 July 2018

1 reference

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Transformation suppressor activity of a Jun transcription factor lacking its activation domain

12 July 2018

1 reference

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Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain

12 July 2018

1 reference

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Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

12 July 2018

1 reference

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Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

12 July 2018

1 reference

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A phosphorylation site located in the NH2-terminal domain of c-Myc increases transactivation of gene expression

12 July 2018

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Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73

12 July 2018

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Transformation and transactivation suppressor activity of the c-Jun leucine zipper fused to a bacterial repressor

12 July 2018

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Extracellular signal-regulated kinases in T cells: characterization of human ERK1 and ERK2 cDNAs

12 July 2018

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Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression

12 July 2018

1 reference

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Function of Ras as a molecular switch in signal transduction

12 July 2018

1 reference

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Inhibition of c-Jun DNA binding by mitogen-activated protein kinase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44131

Regulation of collagen I gene expression by ras

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44131

Signal transduction within the nucleus by mitogen-activated protein kinase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44131

An enhancer element responsive to ras and fms signaling pathways is composed of two distinct nuclear factor binding sites

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44131

Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44131

How many agrins does it take to make a synapse?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44131

Signal transduction. How receptors turn Ras on.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44131

Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8016110

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Co-purification of mitogen-activated protein kinases with phorbol ester-induced c-Jun kinase activity in U937 leukaemic cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8016110

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.91.13.6030

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8016110%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8016110%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

PubMed publication ID

8016110

1 reference