Fosamprenavir : clinical pharmacokinetics and drug interactions of the amprenavir prodrug (Q36399718)

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scientific article

Language	Label	Description	Also known as
English	Fosamprenavir : clinical pharmacokinetics and drug interactions of the amprenavir prodrug	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

1 reference

Europe PubMed Central

Fosamprenavir : clinical pharmacokinetics and drug interactions of the amprenavir prodrug (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Mary Beth Wire

1

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Mark J Shelton

2

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Scott Studenberg

3

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

publication date

1 January 2006

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

45

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

137-168

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Lack of enzyme-inducing effect of rifampicin on the pharmacokinetics of enfuvirtide

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645020-00002

21 January 2018

Effects of rabeprazole, 20 mg, or esomeprazole, 20 mg, on 24-h intragastric pH and serum gastrin in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effervescent and standard formulations of ranitidine--a comparison of their pharmacokinetics and pharmacology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interaction between ketoconazole and amprenavir after single doses in healthy men.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ritonavir increases plasma amprenavir (APV) exposure to a similar extent when coadministered with either fosamprenavir or APV.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between amprenavir and the lopinavir-ritonavir combination in heavily pretreated patients infected with human immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interaction between amprenavir and delavirdine after multiple-dose administration in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salvage therapy with amprenavir, lopinavir and ritonavir 200 mg/d or 400 mg/d in HIV-infected patients in virological failure.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyp3A regulation: from pharmacology to nuclear receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic and pharmacodynamic study of the human immunodeficiency virus protease inhibitor amprenavir after multiple oral dosing

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statistical issues in a modeling approach to assessing bioequivalence or PK similarity with presence of sparsely sampled subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of formulation and dosing strategy on amprenavir concentrations in the seminal plasma of human immunodeficiency virus type 1-infected men.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of multiple doses of ritonavir on the pharmacokinetics of rifabutin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Six-week randomized controlled trial to compare the tolerabilities, pharmacokinetics, and antiviral activities of GW433908 and amprenavir in human immunodeficiency virus type 1-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ex vivo human placental transfer of the anti-HIV nucleoside inhibitor abacavir and the protease inhibitor amprenavir

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genotypic inhibitory quotient as predictor of virological response to ritonavir-amprenavir in human immunodeficiency virus type 1 protease inhibitor-experienced patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ritonavir decreases the nonrenal clearance of digoxin in healthy volunteers with known MDR1 genotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deep salvage with amprenavir and lopinavir/ritonavir: correlation of pharmacokinetics and drug resistance with pharmacodynamics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood--brain barrier.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lopinavir: acute exposure inhibits P-glycoprotein; extended exposure induces P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SOLO: 48-week efficacy and safety comparison of once-daily fosamprenavir /ritonavir versus twice-daily nelfinavir in naive HIV-1-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interaction between amprenavir and clarithromycin in healthy male volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination therapy with amprenavir, abacavir, and efavirenz in human immunodeficiency virus (HIV)-infected patients failing a protease-inhibitor regimen: pharmacokinetic drug interactions and antiviral activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-dose pharmacokinetics of amprenavir, a human immunodeficiency virus type 1 protease inhibitor, in subjects with normal or impaired hepatic function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of adjusted-dose lopinavir-ritonavir combined with rifampin in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maternal-fetal transfer and amniotic fluid accumulation of protease inhibitors in pregnant women who are infected with human immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics of amprenavir, zidovudine, and lamivudine in the genital tracts of men infected with human immunodeficiency virus type 1 (AIDS clinical trials group study 850).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic Interaction between amprenavir and rifabutin or rifampin in healthy males

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic-pharmacodynamic analysis of lopinavir-ritonavir in combination with efavirenz and two nucleoside reverse transcriptase inhibitors in extensively pretreated human immunodeficiency virus-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ritonavir induces P-glycoprotein expression, multidrug resistance-associated protein (MRP1) expression, and drug transporter-mediated activity in a human intestinal cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protease inhibitor ritonavir inhibits the functional activity of the multidrug resistance related-protein 1 (MRP-1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NEAT study: a 48-week open-label study to compare the antiviral efficacy and safety of GW433908 versus nelfinavir in antiretroviral therapy-naive HIV-1-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Esomeprazole provides improved acid control vs. omeprazole In patients with symptoms of gastro-oesophageal reflux disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic study of human immunodeficiency virus protease inhibitors used in combination with amprenavir

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The comparative effects of lansoprazole, omeprazole, and ranitidine in suppressing gastric acid secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and safety of GW433908 and ritonavir, with and without efavirenz, in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of antacids and ranitidine on the single-dose pharmacokinetics of fosamprenavir

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combining fosamprenavir with lopinavir/ritonavir substantially reduces amprenavir and lopinavir exposure: ACTG protocol A5143 results

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interaction between ritonavir and clarithromycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of interaction between enfuvirtide and ritonavir or ritonavir-boosted saquinavir in HIV-1-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of P-glycoprotein and cytochrome P450 3A by HIV protease inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interaction between amprenavir and delavirdine: evidence of induced clearance by amprenavir

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical pharmacology and pharmacokinetics of GW433908, a water-soluble prodrug of the human immunodeficiency virus protease inhibitor amprenavir

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cytochrome P-450 3A (CYP3A) in human intestinal and liver microsomes: comparison of Ki values and impact of CYP3A5 expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamics and kinetics of omeprazole MUPS 20 mg and pantoprazole 40 mg during repeated oral administration in Helicobacter pylori-negative subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized study investigating the efficacy and safety of amprenavir in combination with low-dose ritonavir in protease inhibitor-experienced HIV-infected adults.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic disposition and pharmacokinetics of [14C]-amprenavir, a human immunodeficiency virus type 1 (HIV-1) protease inhibitor, administered as a single oral dose to healthy male subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of the nuclear receptor PXR to predict drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of P-glycoprotein on the CNS disposition of amprenavir (141W94), an HIV protease inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steady-State pharmacokinetics of saquinavir hard-gel/ritonavir/fosamprenavir in HIV-1-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of indinavir and ritonavir administered at 667 and 100 milligrams, respectively, every 12 hours compared with indinavir administered at 800 milligrams every 8 hours in human immunodeficiency virus-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of methadone enantiomers after coadministration with amprenavir in opioid-dependent subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16485915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00003088-200645020-00002

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

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