Mutations in the SOD2 promoter reveal a molecular basis for an activating protein 2-dependent dysregulation of manganese superoxide dismutase expression in cancer cells (Q37020835)

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scientific article published on December 2008

Language	Label	Description	Also known as
English	Mutations in the SOD2 promoter reveal a molecular basis for an activating protein 2-dependent dysregulation of manganese superoxide dismutase expression in cancer cells	scientific article published on December 2008

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Mutations in the SOD2 promoter reveal a molecular basis for an activating protein 2-dependent dysregulation of manganese superoxide dismutase expression in cancer cells (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

author name string

Yong Xu

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Fang Fang

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Sanjit K Dhar

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Antonio Bosch

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

William H St Clair

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Edward J Kasarskis

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Daret K St Clair

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 December 2008

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Molecular Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

1881-1893

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Epigenetic regulation of manganese superoxide dismutase expression in human breast cancer cells

1 reference

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29 September 2017

Review. Antioxidant gene therapeutic approaches to normal tissue radioprotection and tumor radiosensitization

1 reference

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29 September 2017

The role of a single-stranded nucleotide loop in transcriptional regulation of the human sod2 gene

1 reference

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29 September 2017

Activator protein-2 in carcinogenesis with a special reference to breast cancer--a mini review

1 reference

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29 September 2017

Nucleophosmin acts as a novel AP2alpha-binding transcriptional corepressor during cell differentiation

1 reference

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29 September 2017

The AP-2 family of transcription factors

1 reference

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p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase

1 reference

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Modulation of skin tumorigenesis by SOD.

1 reference

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Mechanism of the tumor suppressive effect of MnSOD overexpression

1 reference

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29 September 2017

Method for determination of (-102C>T) single nucleotide polymorphism in the human manganese superoxide dismutase promoter

1 reference

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29 September 2017

Mitochondrial superoxide dismutase: a promising target for new anticancer therapies

1 reference

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29 September 2017

Identification of nucleophosmin as an NF-kappaB co-activator for the induction of the human SOD2 gene

1 reference

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29 September 2017

Activator protein 2alpha inhibits tumorigenicity and represses vascular endothelial growth factor transcription in prostate cancer cells

1 reference

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29 September 2017

Cell cycle arrest and apoptosis induction by activator protein 2alpha (AP-2alpha) and the role of p53 and p21WAF1/CIP1 in AP-2alpha-mediated growth inhibition

1 reference

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The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2.

1 reference

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Tumor suppressor activity of AP2alpha mediated through a direct interaction with p53.

1 reference

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ROS, stress-activated kinases and stress signaling in cancer

1 reference

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29 September 2017

Transcriptional regulation of the human manganese superoxide dismutase gene: the role of specificity protein 1 (Sp1) and activating protein-2 (AP-2).

1 reference

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29 September 2017

The level of manganese superoxide dismutase content is an independent prognostic factor for glioblastoma. Biological mechanisms and clinical implications

1 reference

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An intronic NF-kappaB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-alpha and interleukin-1beta

1 reference

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29 September 2017

Decreased expression of manganese superoxide dismutase in transformed cells is associated with increased cytosine methylation of the SOD2 gene

1 reference

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29 September 2017

Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605667

29 September 2017

Transcriptional regulation of the 5' proximal promoter of the human manganese superoxide dismutase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605667

29 September 2017

Superoxide dismutases in relation to the overall survival of colorectal cancer patients

1 reference

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RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2.

1 reference

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29 September 2017

Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB.

1 reference

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Regulation of K3 keratin gene transcription by Sp1 and AP-2 in differentiating rabbit corneal epithelial cells.

1 reference

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The level of MnSOD is directly correlated with grade of brain tumours of neuroepithelial origin

1 reference

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Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2

1 reference

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Molecular structure and organization of the human manganese superoxide dismutase gene

1 reference

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Transcription factor AP-2 regulates human insulin-like growth factor binding protein-5 gene expression

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Transcription factor repression and activation of the human acetylcholinesterase gene

1 reference

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Human liver manganese superoxide dismutase. Purification and crystallization, subunit association and sulfhydryl reactivity

1 reference

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Complementary DNA encoding human colon cancer manganese superoxide dismutase and the expression of its gene in human cells

1 reference

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29 September 2017

Role of superoxide dismutase in cancer: a review

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The Biology of Oxygen Radicals

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Suppression of RelB-mediated manganese superoxide dismutase expression reveals a primary mechanism for radiosensitization effect of 1alpha,25-dihydroxyvitamin D(3) in prostate cancer cells

1 reference

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AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

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SOD2: a new type of tumor-suppressor gene?

1 reference

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1 reference

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Differential expression of manganese superoxide dismutase and catalase in lung cancer

1 reference

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Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer.

1 reference

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Enhancement of mitochondrial, cyanide-resistant superoxide dismutase in the livers of rats treated with 2,4-dinitrophenol.

1 reference

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Manganese superoxide dismutase expression correlates with p53 status and local recurrence of cervical carcinoma treated with radiation therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19074833

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adaptive antioxidant response of manganese-superoxide dismutase following repetitive UVA irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19074833

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1541-7786.MCR-08-0253

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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