Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis (Q37322052)

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scientific article published on 21 July 2009

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English	Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis	scientific article published on 21 July 2009

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1 reference

based on heuristic

inferred from title

object named as

Adrienne Boire

2

0 references

author name string

Eric Yang

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Anika Agarwal

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Nga Nguyen

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Katie O'Callaghan

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Powen Tu

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Athan Kuliopulos

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Lidija Covic

8

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

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publication date

21 July 2009

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Europe PubMed Central

PMC publication ID

19 August 2017

Cancer Research

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Europe PubMed Central

PMC publication ID

19 August 2017

69

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Europe PubMed Central

PMC publication ID

19 August 2017

15

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

6223-6231

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Matrix metalloproteinase-1 and thrombin differentially activate gene expression in endothelial cells via PAR-1 and promote angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2733168

6 September 2017

Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2733168

6 September 2017

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

1 reference

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6 September 2017

Management of advanced breast cancer.

1 reference

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6 September 2017

Cancer statistics, 2007

1 reference

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Cancer stem cells: models and concepts

1 reference

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The pattern of Protease Activated Receptor 1 (PAR1) expression in endometrial carcinoma

1 reference

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6 September 2017

Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer

1 reference

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6 September 2017

Perturbations of the AKT signaling pathway in human cancer

1 reference

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6 September 2017

Activation of AKT kinases in cancer: implications for therapeutic targeting

1 reference

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Randomized phase III trial of marimastat versus placebo in patients with metastatic breast cancer who have responding or stable disease after first-line chemotherapy: Eastern Cooperative Oncology Group trial E2196

1 reference

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6 September 2017

PAR1-type thrombin receptor stimulates migration and matrix adhesion of human colon carcinoma cells by a PKCepsilon-dependent mechanism

1 reference

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6 September 2017

Protease-activated receptors: contribution to physiology and disease

1 reference

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Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides

1 reference

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Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor

1 reference

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Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

1 reference

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Thrombin receptor overexpression in malignant and physiological invasion processes

1 reference

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Matrix metalloproteinase-1 is associated with poor prognosis in colorectal cancer

1 reference

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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1 reference

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6 September 2017

Protease-activated receptor-1 (hPar1), a survival factor eliciting tumor progression

1 reference

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14 September 2017

Tumor-derived Cyr61(CCN1) promotes stromal matrix metalloproteinase-1 production and protease-activated receptor 1-dependent migration of breast cancer cells

1 reference

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14 September 2017

PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2733168

14 September 2017

Signaling from protease-activated receptor-1 inhibits migration and invasion of breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2733168

28 September 2017

Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2733168

26 June 2018

Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2733168

26 June 2018

Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines

1 reference

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Molecular breast cancer subtypes in premenopausal and postmenopausal African-American women: age-specific prevalence and survival

1 reference

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2 September 2018

Protease-activated receptor-induced Akt activation--regulation and possible function

1 reference

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Discovery of potent orally active thrombin receptor (protease activated receptor 1) antagonists as novel antithrombotic agents

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1 reference

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Differential expression of protease activated receptor 1 (Par1) and pY397FAK in benign and malignant human ovarian tissue samples

1 reference

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Akt Activation in Platelets Depends on Gi Signaling Pathways

1 reference

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HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells.

1 reference

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Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin

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Plasmin Desensitization of the PAR1 Thrombin Receptor: Kinetics, Sites of Truncation, and Implications for Thrombolytic Therapy†

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19622769

12 December 2020

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inferred from PubMed ID database lookup

Protease activation and cleavage of poly(ADP-ribose) polymerase: an integral part of apoptosis in response to photodynamic treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19622769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase-1 is associated with poor prognosis in oesophageal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19622769

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19622769

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High MMP-1 mRNA expression is a risk factor for disease-free and overall survivals in patients with invasive breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19622769

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Matrix metalloproteinase expression and outcome in patients with breast cancer: analysis of a published database

1 reference

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12 December 2020

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Identifiers

10.1158/0008-5472.CAN-09-0187

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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