Pages that link to "Q35636109"
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The following pages link to In vitro and in vivo characterization of PF-04418948, a novel, potent and selective prostaglandin EP₂ receptor antagonist (Q35636109):
Displaying 50 items.
- Structural features of subtype-selective EP receptor modulators (Q26738309) (← links)
- Reciprocal crosstalk between dendritic cells and natural killer cells under the effects of PGE2 in immunity and immunopathology (Q26825075) (← links)
- Activation of the Sigma-1 receptor by haloperidol metabolites facilitates brain-derived neurotrophic factor secretion from human astroglia (Q29248190) (← links)
- The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors (Q30486707) (← links)
- Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection (Q33651797) (← links)
- Lead optimization studies of cinnamic amide EP2 antagonists (Q33654575) (← links)
- Prostanoid receptor EP2 as a therapeutic target (Q33711678) (← links)
- Development of second generation EP2 antagonists with high selectivity (Q33939410) (← links)
- Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2. (Q34155940) (← links)
- Role of prostaglandins in spinal transmission of the exercise pressor reflex in decerebrated rats (Q34183893) (← links)
- Big opportunities for small molecules in immuno-oncology (Q34487689) (← links)
- Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets? (Q34494513) (← links)
- Transforming growth factor-β induces microRNA-29b to promote murine alveolar macrophage dysfunction after bone marrow transplantation (Q34801214) (← links)
- Angiogenesis in the primate ovulatory follicle is stimulated by luteinizing hormone via prostaglandin E2. (Q35617075) (← links)
- At last, a truly selective EP₂ receptor antagonist (Q35636106) (← links)
- A novel 3D high-content assay identifies compounds that prevent fibroblast invasion into tissue surrogates (Q35811284) (← links)
- Activation of EP4 receptors prevents endotoxin-induced neutrophil infiltration into the airways and enhances microvascular barrier function (Q36036213) (← links)
- Oxidized Phospholipid OxPAPC Activates TRPA1 and Contributes to Chronic Inflammatory Pain in Mice (Q36182049) (← links)
- Role of prostaglandin receptor EP2 in the regulations of cancer cell proliferation, invasion, and inflammation. (Q36573214) (← links)
- Selectivity profiling of the novel EP2 receptor antagonist, PF-04418948, in functional bioassay systems: atypical affinity at the guinea pig EP2 receptor. (Q36603195) (← links)
- Role of EP2 and EP4 receptors in airway microvascular leak induced by prostaglandin E2. (Q36796418) (← links)
- Evaluation of WO 2012/177618 A1 and US-2014/0179750 A1: novel small molecule antagonists of prostaglandin-E2 receptor EP2. (Q36833728) (← links)
- Differential effects of prostaglandin E2-sensitive receptors on contractility of human ocular cells that regulate conventional outflow (Q37035691) (← links)
- Discovery and characterization of carbamothioylacrylamides as EP2 selective antagonists. (Q37063800) (← links)
- Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy (Q37079141) (← links)
- Inhibition of protein translation as a novel mechanism for prostaglandin E2 regulation of cell functions (Q37405220) (← links)
- Prostaglandin E2 regulates its own inactivating enzyme, 15-PGDH, by EP2 receptor-mediated cervical cell-specific mechanisms (Q37616877) (← links)
- Prostaglandin E2 inhibits neutrophil extracellular trap formation through production of cyclic AMP. (Q37686116) (← links)
- EP2 receptor antagonism reduces peripheral and central hyperalgesia in a preclinical mouse model of endometriosis (Q37692289) (← links)
- Use of PD biomarkers to drive dose selection and early clinical decision making (Q38060202) (← links)
- PGE2 maintains the tone of the guinea pig trachea through a balance between activation of contractile EP1 receptors and relaxant EP2 receptors (Q39970523) (← links)
- The anti-inflammatory effects of PGE2 on human lung macrophages are mediated by the EP4 receptor (Q40599018) (← links)
- Mapping PTGERs to the Ovulatory Follicle: Regional Responses to the Ovulatory PGE2 Signal (Q41132032) (← links)
- Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells (Q41561509) (← links)
- Characterization of the EP receptor subtype that mediates the inhibitory effects of prostaglandin E2 on IgE-dependent secretion from human lung mast cells (Q42710611) (← links)
- Prostaglandin E2-EP2 signaling as a node of chronic inflammation in the colon tumor microenvironment (Q47157740) (← links)
- Microglia control the glycinergic but not the GABAergic synapses via prostaglandin E2 in the spinal cord. (Q48112946) (← links)
- Prostaglandin E2 Upregulated Trigeminal Ganglionic Sodium Channel 1.7 Involving Temporomandibular Joint Inflammatory Pain in Rats (Q50667654) (← links)
- Prostaglandin E2 potentiates interferon-γ-induced nitric oxide production in cultured rat microglia (Q51265925) (← links)
- PDGF-BB regulates the pulmonary vascular tone: impact of prostaglandins, calcium, MAPK- and PI3K/AKT/mTOR signalling and actin polymerisation in pulmonary veins of guinea pigs. (Q55378794) (← links)
- Peripherally derived macrophages modulate microglial function to reduce inflammation after CNS injury (Q57454605) (← links)
- Prostanoid EP₂ Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells (Q58178283) (← links)
- Peripherally restricted, highly potent, selective, aqueous-soluble EP2 antagonist with anti-inflammatory properties (Q58608077) (← links)
- Novel high-throughput myofibroblast assays identify agonists with therapeutic potential in pulmonary fibrosis that act via EP2 and EP4 receptors (Q60049594) (← links)
- The cyclooxygenase-1/mPGES-1/endothelial prostaglandin EP4 receptor pathway constrains myocardial ischemia-reperfusion injury (Q64097624) (← links)
- Identification of Specific Components of the Eicosanoid Biosynthetic and Signaling Pathway Involved in Pathological Inflammation during Intra-abdominal Infection with Candida albicans and Staphylococcus aureus (Q88595312) (← links)
- Selective EP2 and Cox-2 inhibition suppresses cell migration by reversing epithelial-to-mesenchymal transition and Cox-2 overexpression and E-cadherin downregulation are implicated in neck metastasis of hypopharyngeal cancer (Q91742634) (← links)
- Corrigendum (Q93559220) (← links)
- PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function (Q95832659) (← links)
- Prostaglandin E2 breaks down pericyte-endothelial cell interaction via EP1 and EP4-dependent downregulation of pericyte N-cadherin, connexin-43, and R-Ras (Q97418387) (← links)