Pages that link to "Q41236881"
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The following pages link to Ubiquitination-dependent proteolysis of O6-methylguanine-DNA methyltransferase in human and murine tumor cells following inactivation with O6-benzylguanine or 1,3-bis(2-chloroethyl)-1-nitrosourea (Q41236881):
Displaying 50 items.
- hMutS alpha is protected from ubiquitin-proteasome-dependent degradation by atypical protein kinase C zeta phosphorylation (Q24299514) (← links)
- Labeling of fusion proteins with synthetic fluorophores in live cells (Q24564435) (← links)
- O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients (Q24607903) (← links)
- Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding (Q27622042) (← links)
- Induction of thermal and chemical stability of O6-methylguanine-DNA methyltransferase by Ca2+ (Q28572784) (← links)
- Understanding and manipulating O6-methylguanine-DNA methyltransferase expression (Q30428760) (← links)
- Mechanism to trigger unfolding in O(6) -alkylguanine-DNA alkyltransferase (Q30428783) (← links)
- Point mutations at multiple sites including highly conserved amino acids maintain activity, but render O6-alkylguanine-DNA alkyltransferase insensitive to O6-benzylguanine (Q30854723) (← links)
- Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors (Q33416431) (← links)
- Human DNA repair systems: an overview (Q33536382) (← links)
- Conserved structural motifs governing the stoichiometric repair of alkylated DNA by O(6)-alkylguanine-DNA alkyltransferase (Q34006340) (← links)
- Repair of O6-methylguanine adducts in human telomeric G-quadruplex DNA by O6-alkylguanine-DNA alkyltransferase. (Q34115421) (← links)
- Expression of O-Alkylguanine-DNA Alkyltransferase in Normal and Malignant Bladder Tissue of Egyptian Patients (Q34218598) (← links)
- Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer (Q34288659) (← links)
- O6-methylguanine-DNA methyltransferase in the defense against N-nitroso compounds and colorectal cancer (Q34362828) (← links)
- DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes. (Q34367279) (← links)
- A genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas (Q34427825) (← links)
- O6-alkylguanine-DNA alkyltransferase: role in carcinogenesis and chemotherapy (Q34561510) (← links)
- DNA repair mechanisms in dividing and non-dividing cells (Q34727858) (← links)
- S-nitrosylation from GSNOR deficiency impairs DNA repair and promotes hepatocarcinogenesis (Q34904694) (← links)
- Human colorectal mucosal O6-alkylguanine DNA-alkyltransferase activity and DNA-N7-methylguanine levels in colorectal adenoma cases and matched referents (Q35761394) (← links)
- Current trends in targeted therapies for glioblastoma multiforme (Q35864226) (← links)
- Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung (Q35920833) (← links)
- DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy (Q36012002) (← links)
- Human variants of O6-alkylguanine-DNA alkyltransferase (Q36073920) (← links)
- Epigenetic silencing of the MGMT gene in cancer. (Q36226129) (← links)
- Lesion-specific DNA-binding and repair activities of human O⁶-alkylguanine DNA alkyltransferase (Q36305675) (← links)
- CpG methylation of MGMT and hMLH1 promoter in hepatocellular carcinoma associated with hepatitis viral infection. (Q36649118) (← links)
- DNA alkylation and DNA methylation: cooperating mechanisms driving the formation of colorectal adenomas and adenocarcinomas? (Q36752507) (← links)
- Tumor-associated mutations in O⁶ -methylguanine DNA-methyltransferase (MGMT) reduce DNA repair functionality (Q37038938) (← links)
- Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice (Q37052491) (← links)
- Expression of O(6)-Methylguanine-DNA Methyltransferase Examined by Alkyl-Transfer Assays, Methylation-Specific PCR and Western Blots in Tumors and Matched Normal Tissue (Q37087445) (← links)
- Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkylguanine transferase (Q37114760) (← links)
- New insights into estrogenic regulation of O6-methylguanine DNA-methyltransferase (MGMT) in human breast cancer cells: Co-degradation of ER-α and MGMT proteins by fulvestrant or O6-benzylguanine indicates fresh avenues for therapy (Q37300127) (← links)
- Degradation of BRCA2 in alkyltransferase-mediated DNA repair and its clinical implications (Q37311285) (← links)
- Topologies of complexes containing O6-alkylguanine-DNA alkyltransferase and DNA. (Q37330168) (← links)
- Development of an O(6)-alkylguanine-DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-3H]O(6)-benzylguanine to the protein (Q37412218) (← links)
- The ubiquitin-proteasome system in cancer, a major player in DNA repair. Part 1: post-translational regulation (Q37517725) (← links)
- Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage (Q37616054) (← links)
- Genomic imprinting in development, growth, behavior and stem cells (Q37715275) (← links)
- Targeting O⁶-methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapy (Q37780712) (← links)
- Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools (Q37861732) (← links)
- DNA repair by reversal of DNA damage (Q38071280) (← links)
- O(6) -alkylguanine-DNA alkyltransferase-mediated repair of O(4) -alkylated 2'-deoxyuridines. (Q38305305) (← links)
- O4-alkyl-2'-deoxythymidine cross-linked DNA to probe recognition and repair by O6-alkylguanine DNA alkyltransferases (Q38323024) (← links)
- Recombinant human O6-alkylguanine-DNA alkyltransferase (AGT), Cys145-alkylated AGT and Cys145 --> Met145 mutant AGT: comparison by isoelectric focusing, CD and time-resolved fluorescence spectroscopy (Q38345918) (← links)
- A mechanism-based fluorescent probe for labeling O6-methylguanine-DNA methyltransferase in live cells (Q39376801) (← links)
- Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells (Q39697091) (← links)
- Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K). (Q39782231) (← links)
- Quantitative digital assessment of MGMT immunohistochemical expression in glioblastoma tissue (Q39967271) (← links)