Pages that link to "Q55473632"

The following pages link to A presenilin 1 mutation associated with familial frontotemporal dementia inhibits gamma-secretase cleavage of APP and notch. (Q55473632):

Displaying 32 items.

• FAD mutants unable to increase neurotoxic Aβ 42 suggest that mutation effects on neurodegeneration may be independent of effects on Aβ (Q22242369) (← links)
• Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1 (Q24302464) (← links)
• Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease (Q24676498) (← links)
• Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene (Q28280248) (← links)
• Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport (Q28512320) (← links)
• Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration (Q28590719) (← links)
• Intracellular calcium deficits in Drosophila cholinergic neurons expressing wild type or FAD-mutant presenilin (Q33500167) (← links)
• Familial dementia with frontotemporal features associated with M146V presenilin-1 mutation (Q33554860) (← links)
• Pharmacological and genetic reversal of age-dependent cognitive deficits attributable to decreased presenilin function (Q34050670) (← links)
• The solved and unsolved mysteries of the genetics of early-onset Alzheimer's disease (Q34851974) (← links)
• Causative and susceptibility genes for Alzheimer's disease: a review. (Q35146030) (← links)
• The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism (Q35578655) (← links)
• Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration. (Q35844774) (← links)
• Advances in the pathogenesis of Alzheimer's disease: a re-evaluation of amyloid cascade hypothesis (Q36478423) (← links)
• Frontotemporal dementia-like phenotypes associated with presenilin-1 mutations (Q36583604) (← links)
• Synaptic dysfunction and oxidative stress in Alzheimer's disease: emerging mechanisms. (Q36600440) (← links)
• Effect of Presenilin Mutations on APP Cleavage; Insights into the Pathogenesis of FAD (Q36674203) (← links)
• Frontotemporal lobar degeneration: current concepts in the light of recent advances (Q36817228) (← links)
• Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations (Q37199229) (← links)
• Neuropathology of hereditary forms of frontotemporal dementia and parkinsonism. (Q37217970) (← links)
• gamma-secretases: from cell biology to therapeutic strategies (Q37686625) (← links)
• Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations (Q37702630) (← links)
• Correlating familial Alzheimer's disease gene mutations with clinical phenotype (Q37730015) (← links)
• Presenilins in synaptic function and disease (Q37906902) (← links)
• Transgenic mouse models of Alzheimer disease: developing a better model as a tool for therapeutic interventions (Q37979824) (← links)
• Familial Presenilin Mutations and Sporadic Alzheimer's Disease Pathology: Is the Assumption of Biochemical Equivalence Justified? (Q38693441) (← links)
• ubiquilin antagonizes presenilin and promotes neurodegeneration in Drosophila (Q43442095) (← links)
• Neurobiology: double trouble for neurons (Q44611192) (← links)
• Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice. (Q46610675) (← links)
• Formation of tau inclusions in knock-in mice with familial Alzheimer disease (FAD) mutation of presenilin 1 (PS1). (Q46798292) (← links)
• Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia (Q92215030) (← links)
• Neuron-specific deletion of presenilin enhancer2 causes progressive astrogliosis and age-related neurodegeneration in the cortex independent of the Notch signaling (Q99603845) (← links)