Pages that link to "Q22010912"
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The following pages link to Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity (Q22010912):
Displaying 50 items.
- Beta-secretase 2 (Q4897229) (← links)
- Octyl gallate markedly promotes anti-amyloidogenic processing of APP through estrogen receptor-mediated ADAM10 activation (Q21132562) (← links)
- The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice (Q21195685) (← links)
- A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline (Q22251083) (← links)
- Expression analysis of BACE2 in brain and peripheral tissues (Q22253458) (← links)
- Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing (Q24290265) (← links)
- X11 alpha and x11 beta interact with presenilin-1 via their PDZ domains (Q24290528) (← links)
- BACE2 functions as an alternative alpha-secretase in cells (Q24291363) (← links)
- The transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate (Q24291471) (← links)
- PAR-4 is involved in regulation of beta-secretase cleavage of the Alzheimer amyloid precursor protein (Q24292718) (← links)
- Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase (Q24292869) (← links)
- Identification of phospholipid scramblase 1 as a novel interacting molecule with beta -secretase (beta -site amyloid precursor protein (APP) cleaving enzyme (BACE)) (Q24294704) (← links)
- Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme (Q24300851) (← links)
- Antagonistic effects of beta-site amyloid precursor protein-cleaving enzymes 1 and 2 on beta-amyloid peptide production in cells (Q24304445) (← links)
- Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage (Q24312009) (← links)
- GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production (Q24336029) (← links)
- BACE (beta-secretase) modulates the processing of APLP2 in vivo (Q24336570) (← links)
- Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing (Q24338519) (← links)
- Flotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sorting (Q24338925) (← links)
- The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: characterizing a new regulatory motif (Q24600203) (← links)
- Biological markers of amyloid beta-related mechanisms in Alzheimer's disease (Q24622136) (← links)
- Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients (Q24633400) (← links)
- BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein (Q24675964) (← links)
- The amyloid precursor protein: beyond amyloid (Q24680465) (← links)
- Pro-domain removal in ASP-2 and the cleavage of the amyloid precursor are influenced by pH (Q24803627) (← links)
- Stepping closer to treating Alzheimer's disease patients with BACE1 inhibitor drugs (Q26740189) (← links)
- Amyloid Proteins and Their Role in Multiple Sclerosis. Considerations in the Use of Amyloid-PET Imaging (Q26750249) (← links)
- TDP-43: a new player on the AD field? (Q26823723) (← links)
- The role of APP and BACE1 trafficking in APP processing and amyloid-β generation (Q26825686) (← links)
- Trafficking regulation of proteins in Alzheimer's disease (Q26825722) (← links)
- Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease (Q26999922) (← links)
- Toward the structure of presenilin/γ-secretase and presenilin homologs (Q27002018) (← links)
- General anesthetics and β-amyloid protein (Q27010208) (← links)
- Computational Insights into Substrate and Site Specificities, Catalytic Mechanism, and Protonation States of the Catalytic Asp Dyad of β -Secretase (Q27026144) (← links)
- Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor (Q27627346) (← links)
- Structural studies of the Alzheimer's amyloid precursor protein copper-binding domain reveal how it binds copper ions (Q27643593) (← links)
- Potent and selective isophthalamide S2 hydroxyethylamine inhibitors of BACE1 (Q27644455) (← links)
- Thiophene substituted acylguanidines as BACE1 inhibitors (Q27647677) (← links)
- Structure of Alzheimer's disease amyloid precursor protein copper-binding domain at atomic resolution (Q27648688) (← links)
- BACE-1 inhibitors part 1: identification of novel hydroxy ethylamines (HEAs) (Q27649468) (← links)
- Crystal Structure of an Active Form of BACE1, an Enzyme Responsible for Amyloid Protein Production (Q27650198) (← links)
- Second generation of hydroxyethylamine BACE-1 inhibitors: optimizing potency and oral bioavailability (Q27650533) (← links)
- Structure-based design and synthesis of macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors (Q27653661) (← links)
- Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo (Q27653662) (← links)
- Discovery of aminoheterocycles as a novel beta-secretase inhibitor class: pH dependence on binding activity part 1 (Q27655352) (← links)
- Second generation of BACE-1 inhibitors. Part 1: The need for improved pharmacokinetics (Q27655431) (← links)
- Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core (Q27658789) (← links)
- Discovery of cyclic acylguanidines as highly potent and selective beta-site amyloid cleaving enzyme (BACE) inhibitors: Part I--inhibitor design and validation (Q27658825) (← links)
- Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors (Q27666907) (← links)
- Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer Disease (Q27674362) (← links)