Pages that link to "Q28252234"
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The following pages link to Lyn associates with the juxtamembrane region of c-Kit and is activated by stem cell factor in hematopoietic cell lines and normal progenitor cells (Q28252234):
Displaying 50 items.
- Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor (Q22010151) (← links)
- Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis (Q24291603) (← links)
- Lyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitors (Q24305025) (← links)
- Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor (Q24318673) (← links)
- The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-Kit (Q24535600) (← links)
- Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells (Q26740953) (← links)
- Functional deregulation of KIT: link to mast cell proliferative diseases and other neoplasms (Q26995624) (← links)
- Crystal structures of the Lyn protein tyrosine kinase domain in its Apo- and inhibitor-bound state (Q27652762) (← links)
- A pyrrolo-pyrimidine derivative targets human primary AML stem cells in vivo (Q27684428) (← links)
- Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosis (Q28080034) (← links)
- Early signaling pathways activated by c-Kit in hematopoietic cells (Q28139288) (← links)
- Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction (Q28145948) (← links)
- Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling (Q28217308) (← links)
- KIT associated intracellular tyrosines play an essential role in EpoR co-signaling (Q28588986) (← links)
- The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling (Q30565546) (← links)
- The biology of stem cell factor and its receptor C-kit (Q33785129) (← links)
- Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation (Q33925269) (← links)
- Kit signal transduction (Q33979008) (← links)
- Dasatinib inhibits the growth of molecularly heterogeneous myeloid leukemias (Q34335004) (← links)
- Recent advances in the understanding of mastocytosis: the role of KIT mutations. (Q34635424) (← links)
- Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease (Q34658532) (← links)
- Dasatinib targets B-lineage cells but does not provide an effective therapy for myeloproliferative disease in c-Cbl RING finger mutant mice (Q35144330) (← links)
- Role of intracellular tyrosines in activating KIT-induced myeloproliferative disease (Q35230318) (← links)
- Balanced interactions between Lyn, the p85alpha regulatory subunit of class I(A) phosphatidylinositol-3-kinase, and SHIP are essential for mast cell growth and maturation (Q35274032) (← links)
- Targeting mutated tyrosine kinases in the therapy of myeloid leukaemias (Q35782893) (← links)
- Signal transduction and chemotaxis in mast cells (Q36240848) (← links)
- Functions of the Lyn tyrosine kinase in health and disease (Q36299576) (← links)
- Crosstalk between BCR/ABL oncoprotein and CXCR4 signaling through a Src family kinase in human leukemia cells (Q36371049) (← links)
- Stem cell factor expression, mast cells and inflammation in asthma (Q36382616) (← links)
- Physical and functional association of the Src family kinases Fyn and Lyn with the collagen receptor glycoprotein VI-Fc receptor gamma chain complex on human platelets (Q36401453) (← links)
- Primordial germ cells and gastrointestinal stromal tumors respond distinctly to a cKit overactivating allele (Q36477671) (← links)
- Pharmacological targeting of the KIT growth factor receptor: a therapeutic consideration for mast cell disorders (Q36842503) (← links)
- Role of tyrosine phosphorylation in ligand-induced regulation of transcytosis of the polymeric Ig receptor (Q36888712) (← links)
- A KIT juxtamembrane PY567 -directed pathway provides nonredundant signals for erythroid progenitor cell development and stress erythropoiesis (Q37240757) (← links)
- The potential for dasatinib in treating chronic lymphocytic leukemia, acute myeloid leukemia, and myeloproliferative neoplasms (Q37861186) (← links)
- Beginning of personalized medicine in Panama: Molecular and pathological characteristics of gastrointestinal stromal tumors from archival paraffin-embedded tissue (Q38401861) (← links)
- Lyn kinase plays important roles in erythroid expansion, maturation and erythropoietin receptor signalling by regulating inhibitory signalling pathways that control survival. (Q39022552) (← links)
- Reconstitution of a cytokine receptor scaffold utilizing multiple different tyrosine motifs. (Q39138441) (← links)
- New findings of kinase switching in gastrointestinal stromal tumor under imatinib using phosphoproteomic analysis. (Q39146365) (← links)
- Caspase-8: regulating life and death (Q39277461) (← links)
- Proteogenomics for the Study of Gastrointestinal Stromal Tumors (Q39337577) (← links)
- The stem cell factor (SCF)/c-KIT signalling in testis and prostate cancer (Q39401758) (← links)
- Kit transduced signals counteract erythroid maturation by MAPK-dependent modulation of erythropoietin signaling and apoptosis induction in mouse fetal liver (Q39468881) (← links)
- Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region. (Q39745856) (← links)
- Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD. (Q40182148) (← links)
- Tyrosine phosphorylation regulates maturation of receptor tyrosine kinases (Q40435143) (← links)
- c-Kit-mediated overlapping and unique functional and biochemical outcomes via diverse signaling pathways. (Q40468905) (← links)
- Synergistic growth of stem cell factor and granulocyte macrophage colony-stimulating factor involves kinase-dependent and -independent contributions from c-Kit (Q40525943) (← links)
- Src family kinases are involved in the differential signaling from two splice forms of c-Kit (Q40679645) (← links)
- Functional and biochemical consequences of abrogating the activation of multiple diverse early signaling pathways in Kit. Role for Src kinase pathway in Kit-induced cooperation with erythropoietin receptor (Q40683030) (← links)