Pages that link to "Q33936969"

The following pages link to RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model (Q33936969):

Displaying 50 items.

• Oligonucleotide therapeutic approaches for Huntington disease (Q22306293) ‎ (← links)
• SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model (Q24307703) ‎ (← links)
• Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model (Q24535603) ‎ (← links)
• Preclinical safety of RNAi-mediated HTT suppression in the rhesus macaque as a potential therapy for Huntington's disease (Q24626259) ‎ (← links)
• CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup (Q24644358) ‎ (← links)
• Neuroprotective effects of inositol 1,4,5-trisphosphate receptor C-terminal fragment in a Huntington's disease mouse model (Q24647950) ‎ (← links)
• Optimization of feline immunodeficiency virus vectors for RNA interference (Q24671047) ‎ (← links)
• Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice (Q24673105) ‎ (← links)
• Gene, Stem Cell, and Alternative Therapies for SCA 1 (Q26738497) ‎ (← links)
• Transgenic animal models for study of the pathogenesis of Huntington's disease and therapy (Q26849677) ‎ (← links)
• The involvement of microRNAs in neurodegenerative diseases (Q26858788) ‎ (← links)
• Pluripotent stem cells models for Huntington's disease: prospects and challenges (Q26860151) ‎ (← links)
• Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II. (Q27005950) ‎ (← links)
• Mutant huntingtin gene-dose impacts on aggregate deposition, DARPP32 expression and neuroinflammation in HdhQ150 mice (Q27305680) ‎ (← links)
• Reinstating aberrant mTORC1 activity in Huntington's disease mice improves disease phenotypes (Q27306293) ‎ (← links)
• Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice (Q27324749) ‎ (← links)
• Human mutant huntingtin disrupts vocal learning in transgenic songbirds (Q28118833) ‎ (← links)
• Current prospects for RNA interference-based therapies (Q28235733) ‎ (← links)
• Construction of permanently inducible miRNA-based expression vectors using site-specific recombinases (Q28253107) ‎ (← links)
• The roles of intracellular protein-degradation pathways in neurodegeneration (Q28269322) ‎ (← links)
• Normal huntingtin function: an alternative approach to Huntington's disease (Q28281904) ‎ (← links)
• Epigenetic mechanisms of neurodegeneration in Huntington's disease (Q28297936) ‎ (← links)
• Deficiency in the multicopy Sycp3-like X-linked genes Slx and Slxl1 causes major defects in spermatid differentiation (Q28510115) ‎ (← links)
• Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patients (Q28542911) ‎ (← links)
• Dose optimization for long-term rAAV-mediated RNA interference in the nigrostriatal projection neurons (Q28566948) ‎ (← links)
• Study of RNA interference inhibiting rat ovarian androgen biosynthesis by depressing 17alpha-hydroxylase/17, 20-lyase activity in vivo (Q28582335) ‎ (← links)
• Exploring the zebra finch Taeniopygia guttata as a novel animal model for the speech-language deficit of fragile X syndrome (Q28649423) ‎ (← links)
• A novel method for tissue-specific RNAi rescue in Drosophila. (Q30377704) ‎ (← links)
• Therapeutic prospects for spinocerebellar ataxia type 2 and 3. (Q30410969) ‎ (← links)
• Focused ultrasound for targeted delivery of siRNA and efficient knockdown of Htt expression (Q30438915) ‎ (← links)
• Elucidating a normal function of huntingtin by functional and microarray analysis of huntingtin-null mouse embryonic fibroblasts (Q30441792) ‎ (← links)
• A fully humanized transgenic mouse model of Huntington disease. (Q30537951) ‎ (← links)
• AAV vector-mediated RNAi of mutant huntingtin expression is neuroprotective in a novel genetic rat model of Huntington's disease (Q30549911) ‎ (← links)
• Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease (Q30581321) ‎ (← links)
• Huntington disease: natural history, biomarkers and prospects for therapeutics (Q30774172) ‎ (← links)
• The multicopy gene Sly represses the sex chromosomes in the male mouse germline after meiosis (Q30887131) ‎ (← links)
• Quantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into huntington's disease molecular pathogenesis (Q30986761) ‎ (← links)
• Human gene therapy and imaging in neurological diseases (Q31023442) ‎ (← links)
• Designing siRNA that distinguish between genes that differ by a single nucleotide (Q33257088) ‎ (← links)
• Ubiquitin-mediated signalling and Paget's disease of bone (Q33307880) ‎ (← links)
• Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease (Q33374523) ‎ (← links)
• Design of RNAi hairpins for mutation-specific silencing of ataxin-7 and correction of a SCA7 phenotype. (Q33507519) ‎ (← links)
• RNAi reduces expression and intracellular retention of mutant cartilage oligomeric matrix protein (Q33565464) ‎ (← links)
• Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity (Q33572896) ‎ (← links)
• Effects of chemical modification on the potency, serum stability, and immunostimulatory properties of short shRNAs (Q33572902) ‎ (← links)
• Quantification assays for total and polyglutamine-expanded huntingtin proteins (Q33590805) ‎ (← links)
• RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1 (Q33607305) ‎ (← links)
• The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patients (Q33683726) ‎ (← links)
• Artificial microRNAs as siRNA shuttles: improved safety as compared to shRNAs in vitro and in vivo (Q33712990) ‎ (← links)
• Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice. (Q33713689) ‎ (← links)