Pages that link to "Q35752487"
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The following pages link to Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome (Q35752487):
Displaying 50 items.
- Chilblain lupus (Q5097618) (← links)
- Nucleic Acid sensors and type I interferon production in systemic lupus erythematosus (Q21131202) (← links)
- SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations (Q24310328) (← links)
- Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response (Q24338296) (← links)
- Trex1 prevents cell-intrinsic initiation of autoimmunity (Q24648757) (← links)
- Clinical and molecular phenotype of Aicardi-Goutieres syndrome (Q24655458) (← links)
- Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity (Q24655886) (← links)
- Restricting retrotransposons: a review (Q26741496) (← links)
- Type I interferonopathies in pediatric rheumatology (Q26748746) (← links)
- Linking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosus (Q26822662) (← links)
- The enemy within: endogenous retroelements and autoimmune disease (Q27021785) (← links)
- RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA (Q27314893) (← links)
- Structural and biochemical studies of TREX1 inhibition by metals. Identification of a new active histidine conserved in DEDDh exonucleases (Q27652057) (← links)
- The Structure of the Mammalian RNase H2 Complex Provides Insight into RNA⋅DNA Hybrid Processing to Prevent Immune Dysfunction (Q27658230) (← links)
- Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease (Q27675483) (← links)
- How SLX4 cuts through the mystery of HIV-1 Vpr-mediated cell cycle arrest. (Q27693229) (← links)
- Advances in lupus genetics (Q28088718) (← links)
- Recent advances in the genetics of autoimmune disease (Q28238782) (← links)
- Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature (Q28275605) (← links)
- Genes involved in leukodystrophies: a glance at glial functions. (Q31158574) (← links)
- Solving the genetic puzzle of systemic lupus erythematosus (Q33359121) (← links)
- Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutières syndrome (Q33388122) (← links)
- Blood gene expression profiling in pediatric systemic lupus erythematosus and systemic juvenile idiopathic arthritis: from bench to bedside (Q33622723) (← links)
- Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion (Q33636066) (← links)
- New roles for the major human 3'-5' exonuclease TREX1 in human disease (Q33671295) (← links)
- The Arg-62 residues of the TREX1 exonuclease act across the dimer interface contributing to catalysis in the opposing protomers (Q33676423) (← links)
- Interferon-alpha: a therapeutic target in systemic lupus erythematosus (Q33744320) (← links)
- A genomic approach to human autoimmune diseases (Q33762839) (← links)
- RNaseH2 mutants that cause Aicardi-Goutieres syndrome are active nucleases (Q33779326) (← links)
- Spontaneous activation of RNA-sensing pathways in autoimmune disease (Q33909504) (← links)
- IFNαR signaling in effector but not regulatory T cells is required for immune dysregulation during type I IFN-dependent inflammatory disease. (Q34146449) (← links)
- Aicardi-Goutieres syndrome: from patients to genes and beyond (Q34239046) (← links)
- Activated STING in a vascular and pulmonary syndrome (Q34241214) (← links)
- The 3'-5' DNA exonuclease TREX1 directly interacts with poly(ADP-ribose) polymerase-1 (PARP1) during the DNA damage response (Q34552582) (← links)
- STING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells (Q34646599) (← links)
- Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease (Q34719398) (← links)
- Aicardi-Goutieres syndrome. (Q34917298) (← links)
- Vicious circle: systemic autoreactivity in Ro52/TRIM21-deficient mice (Q34994387) (← links)
- Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort (Q35022304) (← links)
- Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome (Q35213485) (← links)
- Defective removal of ribonucleotides from DNA promotes systemic autoimmunity. (Q35242453) (← links)
- The TREX1 exonuclease R114H mutation in Aicardi-Goutières syndrome and lupus reveals dimeric structure requirements for DNA degradation activity (Q35562735) (← links)
- Animal Models of Interferon Signature Positive Lupus (Q35686914) (← links)
- Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease (Q35717955) (← links)
- Lenalidomide therapy in treatment-refractory cutaneous lupus erythematosus: histologic and circulating leukocyte profile and potential risk of a systemic lupus flare (Q35836605) (← links)
- Human DNA Exonuclease TREX1 Is Also an Exoribonuclease That Acts on Single-stranded RNA. (Q35860984) (← links)
- The interferon-regulated gene signature is elevated in subacute cutaneous lupus erythematosus and discoid lupus erythematosus and correlates with the cutaneous lupus area and severity index score (Q35911498) (← links)
- Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome (Q35925694) (← links)
- Modes of retrotransposition of long interspersed element-1 by environmental factors (Q35999488) (← links)
- Tocilizumab reverses cerebral vasculopathy in a patient with homozygous SAMHD1 mutation (Q36307015) (← links)