Pages that link to "Q36741538"

The following pages link to Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation (Q36741538):

Displaying 50 items.

• Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS (Q24297462) (← links)
• Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking (Q24300438) (← links)
• TARDBP mutation analysis in TDP-43 proteinopathies and deciphering the toxicity of mutant TDP-43 (Q24594172) (← links)
• ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import (Q24630100) (← links)
• A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions (Q24632492) (← links)
• Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability (Q24648173) (← links)
• Redox Imbalance and Viral Infections in Neurodegenerative Diseases (Q26750630) (← links)
• The extreme N-terminus of TDP-43 mediates the cytoplasmic aggregation of TDP-43 and associated toxicity in vivo (Q26751400) (← links)
• Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders (Q26828357) (← links)
• Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis (Q26863439) (← links)
• The function of RNA-binding proteins at the synapse: implications for neurodegeneration (Q26991684) (← links)
• Therapeutic and diagnostic challenges for frontotemporal dementia (Q26998919) (← links)
• ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation (Q27301374) (← links)
• Recruitment of the oncoprotein v-ErbA to aggresomes. (Q27308854) (← links)
• Hyperphosphorylation as a defense mechanism to reduce TDP-43 aggregation (Q27325625) (← links)
• TDP-43 aggregation in neurodegeneration: are stress granules the key? (Q27692111) (← links)
• TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets (Q28080628) (← links)
• Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis (Q28236796) (← links)
• TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia (Q28294001) (← links)
• Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis (Q28473603) (← links)
• Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue (Q28475724) (← links)
• β-amyloid triggers ALS-associated TDP-43 pathology in AD models (Q28580544) (← links)
• Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis (Q28730723) (← links)
• TDP-43 is a transcriptional repressor: the testis-specific mouse acrv1 gene is a TDP-43 target in vivo (Q30427637) (← links)
• A90V TDP-43 variant results in the aberrant localization of TDP-43 in vitro (Q30482763) (← links)
• Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6 (Q30492839) (← links)
• TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration (Q30493749) (← links)
• Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis (Q30494776) (← links)
• Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy (Q30499509) (← links)
• ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. (Q30536540) (← links)
• Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy. (Q30537986) (← links)
• The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation (Q30541099) (← links)
• Selective forelimb impairment in rats expressing a pathological TDP-43 25 kDa C-terminal fragment to mimic amyotrophic lateral sclerosis (Q30541190) (← links)
• Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons (Q30543660) (← links)
• A high-content screen identifies novel compounds that inhibit stress-induced TDP-43 cellular aggregation and associated cytotoxicity. (Q30570770) (← links)
• Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species (Q30574024) (← links)
• Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS. (Q30655551) (← links)
• TDP-43 is not a common cause of sporadic amyotrophic lateral sclerosis (Q33342840) (← links)
• Astrocytic TDP-43 pathology in Alexander disease (Q33575134) (← links)
• Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD. (Q33614771) (← links)
• Elucidating the genetics and pathology of Perry syndrome (Q33618272) (← links)
• Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins (Q33622382) (← links)
• Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis (Q33649745) (← links)
• Mutations in spliceosomal proteins and retina degeneration (Q33739682) (← links)
• Formation and spreading of TDP-43 aggregates in cultured neuronal and glial cells demonstrated by time-lapse imaging (Q33783811) (← links)
• The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism (Q33786698) (← links)
• The role of transactive response DNA-binding protein-43 in amyotrophic lateral sclerosis and frontotemporal dementia (Q33847532) (← links)
• TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97. (Q33932237) (← links)
• Neuronal function and dysfunction of Drosophila dTDP (Q33932740) (← links)
• TAR DNA-binding protein 43 in neurodegenerative disease (Q33941040) (← links)