Pages that link to "Q38352373"
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The following pages link to Regulation of mutant p53 temperature-sensitive DNA binding. (Q38352373):
Displaying 50 items.
- ei24, a p53 response gene involved in growth suppression and apoptosis (Q22010923) (← links)
- The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression (Q24533291) (← links)
- p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner (Q24643993) (← links)
- Thermodynamic stability of wild-type and mutant p53 core domain (Q24648879) (← links)
- Interaction of p53 with the CCT complex promotes protein folding and wild-type p53 activity (Q28000133) (← links)
- The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract (Q28141340) (← links)
- Phosphorylation and hsp90 binding mediate heat shock stabilization of p53 (Q28214608) (← links)
- Activation of the p53-p21(Cip1) pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes (Q28580587) (← links)
- Factors governing loss and rescue of DNA binding upon single and double mutations in the p53 core domain (Q30682940) (← links)
- Allosteric drugs: thinking outside the active-site box. (Q30868722) (← links)
- Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound. (Q31041084) (← links)
- Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors. (Q33209208) (← links)
- Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer (Q33300777) (← links)
- tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors (Q33722903) (← links)
- Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress. (Q33967914) (← links)
- A cytoplasmic negative regulator isoform of ATF7 impairs ATF7 and ATF2 phosphorylation and transcriptional activity (Q33999494) (← links)
- Strategies for manipulating the p53 pathway in the treatment of human cancer. (Q34076012) (← links)
- Effects of temperature on the p53-DNA binding interactions and their dynamical behavior: comparing the wild type to the R248Q mutant. (Q34081676) (← links)
- Preferential binding of hot spot mutant p53 proteins to supercoiled DNA in vitro and in cells. (Q34651573) (← links)
- JNK targets p53 ubiquitination and degradation in nonstressed cells (Q35208651) (← links)
- Investigating DNA Binding and Conformational Variation in Temperature Sensitive p53 Cancer Mutants Using QM-MM Simulations. (Q35844807) (← links)
- Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides. (Q35946185) (← links)
- Conformation-dependent phosphorylation of p53. (Q36019930) (← links)
- Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2 (Q36174385) (← links)
- Transcriptional regulation by p53: one protein, many possibilities (Q36436698) (← links)
- Reactivation of mutant p53: molecular mechanisms and therapeutic potential (Q36777373) (← links)
- Thyroid tumors: novel insights from proteomic studies. (Q37579897) (← links)
- TP53 mutants in the tower of babel of cancer progression (Q38180665) (← links)
- Relief of p53-mediated telomerase suppression by p73. (Q38330053) (← links)
- Functional dissection of p53 tumor suppressor protein (Q38349795) (← links)
- Stabilization of the p53-DNA Complex by the Nuclear Protein Dmp1α. (Q38838490) (← links)
- Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity (Q39297236) (← links)
- Adenovirus type 12-induced fragility of the human RNU2 locus requires p53 function. (Q39578554) (← links)
- Efficient specific DNA binding by p53 requires both its central and C-terminal domains as revealed by studies with high-mobility group 1 protein (Q39675422) (← links)
- Trp53-dependent DNA-repair is affected by the codon 72 polymorphism (Q40319779) (← links)
- Effects of hyperthermia on p53 protein expression and activity (Q40588000) (← links)
- Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy (Q40774297) (← links)
- Constitutive expression of the cyclin-dependent kinase inhibitor p21 is transcriptionally regulated by the tumor suppressor protein p53. (Q41000380) (← links)
- The N terminus of p53 regulates its dissociation from DNA. (Q42055738) (← links)
- The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo (Q43941701) (← links)
- QM-MM simulations on p53-DNA complex: a study of hot spot and rescue mutants (Q44145204) (← links)
- Biochemical characterization of different conformational states of the Sf9 cell-purified p53His175 mutant protein (Q44410206) (← links)
- Mechanisms of differential activation of target gene promoters by p53 hinge domain mutants with impaired apoptotic function (Q46762294) (← links)
- Mechanism of DNA-binding loss upon single-point mutation in p53. (Q46968480) (← links)
- Targeting mutant p53 for efficient cancer therapy. (Q47291772) (← links)
- p53 can promote mitochondria- and caspase-independent apoptosis. (Q47997538) (← links)
- R248Q mutation--Beyond p53-DNA binding. (Q50797771) (← links)
- APR-246 reactivates mutant p53 by targeting cysteines 124 and 277. (Q52579544) (← links)
- p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements (Q61988945) (← links)
- Long-range regulation of p53 DNA binding by its intrinsically disordered N-terminal transactivation domain (Q62448159) (← links)