tetracycline (Q193045)

participant

1 reference

tetracycline biosynthetic process

product

1 reference

cellular response to tetracycline

reactant

1 reference

response to tetracycline

reactant

1 reference

tetracycline transmembrane transporter activity

cargo

1 reference

tetracycline transmembrane transport

cargo

1 reference

tetracycline:proton antiporter activity

cargo

1 reference

Gene Ontology release 2020-05-02

has use

medication

1 reference

Tetracycline (English)

DrugBank

17 November 2015

Tetracycline skeletal.svg
512 × 270; 9 KB

0 references

mass

444.1533 dalton

1 reference

TETRACYCLINE (English)

imported from Wikimedia project

19 October 2016

discoverer or inventor

Lloyd Conover

1 reference

French Wikipedia

tautomer of

(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboximidic acid

0 references

chemical formula

C₂₂H₂₄N₂O₈

1 reference

World Health Organisation international non-proprietary name

Tetracycline (English)

publication date

17 November 2015

canonical SMILES

CN(C)C1C(=O)C(C(N)=O)=C(O)C2(O)C(=O)C3=C(O)c4c(O)cccc4C(C)(O)C3CC12

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isomeric SMILES

C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O

0 references

1 reference

14 February 2018

tetracycline (English)

1 reference

A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011.

tetracycline (English)

19 October 2016

1 reference

Streptomyces

1 reference

Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion

Streptomyces aureofaciens

9 references

Use of carbon-13 in biosynthetic studies: origin of the malonyl coenzyme A incorporated into tetracycline by Streptomyces aureofaciens

Analysis of the site-specific integration system of the Streptomyces aureofaciens phage μ1/6.

Cloning of a second non-haem bromoperoxidase gene from Streptomyces aureofaciens ATCC 10762: sequence analysis, expression in Streptomyces lividans and enzyme purification

A self-defense gene homologous to tetracycline effluxing gene essential for antibiotic production in Streptomyces aureofaciens

Isolation of pure anhydrotetracycline oxygenase from Streptomyces aureofaciens

Response surface analysis of chlortetracycline and tetracycline production with K-carrageenan immobilized Streptomyces aureofaciens

Characterization of a XhoI isoschizomer in Streptomyces aureofaciens after actinophage infection

Ribosomal proteins of Streptomyces aureofaciens producing tetracycline

Translation initiation factors of a tetracycline-producing strain of Streptomyces aureofaciens.

Streptomyces albus

1 reference

Combinatorial Effect of ARTP Mutagenesis and Ribosome Engineering on an Industrial Strain of Streptomyces albus S12 for Enhanced Biosynthesis of Salinomycin

medical condition treated

1 reference

13 December 2016

2 references

13 December 2016

Drug Indications Extracted from FAERS

2 October 2018

1 reference

13 December 2016

1 reference

13 December 2016

1 reference

gram-negative bacterial infection

13 December 2016

1 reference

peripheral vascular disease

13 December 2016

1 reference

significant drug interaction

13 December 2016

rac-warfarin

retroperitoneal hemorrhage

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tretinoin

pseudotumor cerebri

1 reference

A reference set of clinically relevant adverse drug-drug interactions

acitretin

pseudotumor cerebri

1 reference

A reference set of clinically relevant adverse drug-drug interactions

isotretinoin

pseudotumor cerebri

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pregnancy category

Australian pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

protein synthesis inhibitor

2 references

5 March 2018

Medical Subject Headings

15 March 2018

1 reference

Medical Subject Headings

15 March 2018

0 references

tetracycline antibiotic

1 reference

27 February 2018

2 references

developmental toxicant

start time

1 October 1991

1 reference

California Proposition 65 list of chemicals

https://oehha.ca.gov/chemicals/tetracycline

19 March 2020

reference URL

‎WHO Aware Classification

access

1 reference

2023 ‎AWaRe classification‎

Commons category

Tetracycline

0 references

Identifiers

InChI

InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1

0 references

0 references

CAS Registry Number

60-54-8

2 references

tetracycline (English)

19 November 2016

CAS (formerly Chemical Abstracts Service)

25 January 2022

1 reference

Tetracycline (English)

reason for deprecated rank

19 November 2016

PubChem CID

5353990

cannot be confirmed by other sources

0 references

54675776

2 references

PubChemLite tier0 and tier1

51580080

1 reference

Reaxys registry number

2230417

1 reference

tetracycline (English)

19 October 2016

Gmelin number

1103368

0 references

ChEBI ID

27902

mapping relation type

2 references

TETRACYCLINE (English)

19 November 2016

ChEBI release 2019-10-02

2 references

TETRACYCLINE (English)

19 November 2016

IUPHAR/BPS Guide to PHARMACOLOGY

8 February 2021

2 references

inferred from InChIKey

splash10-0ik9-0402900000-9ef4a0d08180ce9b2a1c

1 reference

MassBank accession ID

0 references

0 references

0 references

0 references

0 references

0 references

splash10-01sc-1900000000-7b792268aeb0a63c32c5

0 references

splash10-01p9-1900000000-da0b69e206bb0369723c

0 references

splash10-000i-3900000000-299e4496b1f8e2f213cc

0 references

HSDB ID

3188

1 reference

Hazardous Substances Data Bank

28 October 2019

TETRACYCLINE (English)

10 May 2021

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

0 references

1 reference

tetracycline (English)

ECHA Substance Infocard ID

19 November 2016

100.000.438

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.000.438

27 December 2018

PesticideInfo chemical ID

Tetracycline (English)

quotation

CAS no.: 60-54-8 (English)

0 references

1 reference

Tetracycline (English)

17 November 2015

1 reference

Tetracycline (English)

17 November 2015

1 reference

Tetracycline (English)

17 November 2015

1 reference

Tetracycline (English)

17 November 2015

1 reference

Tetracycline (English)

17 November 2015

1 reference

Guide to Pharmacology Ligand ID

Tetracycline (English)

publication date

17 November 2015

J01AA

0 references

10927

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

5 February 2021

Tetracycline

0 references

MeSH tree code

D02.455.426.559.847.562.900.875

0 references

0 references

1 reference

tetracycline (English)

19 November 2016

0 references

2 references

inferred from InChIKey

1 reference

tetracycline (English)

MedlinePlus drug identifier

19 November 2016

a682098

0 references

PatientsLikeMe treatment ID

0 references

1 reference

tetracycline (English)

19 November 2016

0 references

1 reference

tetracycline (English)

Australian Educational Vocabulary ID

19 October 2016

PDB ligand ID

TAC

0 references

scot/11352

0 references

Brockhaus Enzyklopädie online ID

0 references

1 reference

California Proposition 65 list of chemicals

https://oehha.ca.gov/chemicals/tetracycline

7 January 2020

reference URL

De Agostini ID

tetraciclina

subject named as

tetraciclina

0 references

0 references

0 references

electronic Essential Medicines List medicine ID

232

0 references

Encyclopædia Britannica Online ID

science/tetracycline

subject named as

tetracycline

0 references

1 reference

28 October 2013

1 reference

9 July 2020

Microsoft Academic ID

0 references

0 references

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

3Q5P (English)

19 October 2016

1 reference

2HCJ (English)

19 October 2016

1 reference

2UXO (English)

19 October 2016

1 reference

2HDN (English)

19 October 2016

1 reference

4V9A (English)

19 October 2016

1 reference

5J7L (English)

19 October 2016

1 reference

2VKE (English)

19 October 2016

1 reference

2TRT (English)

19 October 2016

1 reference

1I97 (English)

19 October 2016

1 reference

1HNW (English)

19 October 2016

1 reference

5J5B (English)

19 October 2016

1 reference

4B3A (English)

19 October 2016

1 reference

1 reference