(RS)-cyclophosphamide (Q408524)

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group of stereoisomers

• cytophosphane
• N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
• 2-[bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
• bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
• (+-)-cyclophosphamide
• anhydrous cyclophosphamide
• cyclophosphamide anhydrous
• cyclophosphamide

edit

Language	Label	Description	Also known as
English	(RS)-cyclophosphamide	group of stereoisomers	cytophosphane N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide 2-[bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide bis(2-chloroethyl)phosphoramide cyclic propanolamide ester (+-)-cyclophosphamide anhydrous cyclophosphamide cyclophosphamide anhydrous cyclophosphamide

Statements

instance of

group of stereoisomers

0 references

subclass of

heterocyclic compound

0 references

part of

response to cyclophosphamide

subject has role

reactant

1 reference

stated in

Gene Ontology release 2019-11-16

has use

medication

0 references

chemical structure

Cyclophosphamid.svg
184 × 201; 6 KB

0 references

mass

260.02482 dalton

1 reference

stated in

PubChem

PubChem CID

2907

language of work or name

English

title

cyclophosphamide (English)

retrieved

3 October 2016

chemical formula

C₇H₁₅Cl₂N₂O₂P

1 reference

stated in

PubChem

PubChem CID

2907

language of work or name

English

title

cyclophosphamide (English)

retrieved

19 November 2016

canonical SMILES

C1CNP(=O)(OC1)N(CCCl)CCCl

1 reference

stated in

PubChem

PubChem CID

2907

language of work or name

English

title

cyclophosphamide (English)

retrieved

19 November 2016

medical condition treated

lymphosarcoma

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

breast cancer

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

Burkitt lymphoma

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

enthesopathy

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

Hodgkin's lymphoma, mixed cellularity

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

autoimmune hemolytic anemia

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

granulomatosis with polyangiitis

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

autoimmune thrombocytopenic purpura

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

mycosis fungoides

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

lung benign neoplasm

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

hemosiderosis

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

Ewing sarcoma

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

chronic lymphocytic leukemia

2 references

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

endometrial carcinoma

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

chronic myeloid leukemia

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

testicular cancer

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

multiple sclerosis

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

macroglobulinemia

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

neuroblastoma

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

acute myeloid leukemia

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

nephrotic syndrome

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

multiple myeloma

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

myasthenia gravis

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

lymphoid leukemia

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

pure red-cell aplasia

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

familial retinoblastoma

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

systemic lupus erythematosus

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

ovarian cancer

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

rhabdomyosarcoma

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

lupus nephritis

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

retrieved

13 December 2016

diffuse large B-cell lymphoma

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

Burkitt lymphoma

start time

12 April 1960

approved by

Food and Drug Administration

1 reference

stated in

Inxight: Drugs Database

retrieved

2 November 2018

reference URL

https://drugs.ncats.io/drug/6UXW23996M

http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf

mycosis fungoides

start time

12 April 1960

approved by

Food and Drug Administration

1 reference

stated in

Inxight: Drugs Database

retrieved

2 November 2018

reference URL

https://drugs.ncats.io/drug/6UXW23996M

http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf

Hodgkin's lymphoma, mixed cellularity

start time

12 April 1960

approved by

Food and Drug Administration

1 reference

stated in

Inxight: Drugs Database

retrieved

2 November 2018

reference URL

https://drugs.ncats.io/drug/6UXW23996M

http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf

breast carcinoma

start time

12 April 1960

approved by

Food and Drug Administration

1 reference

stated in

Inxight: Drugs Database

retrieved

2 November 2018

reference URL

https://drugs.ncats.io/drug/6UXW23996M

http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf

retinoblastoma

start time

12 April 1960

approved by

Food and Drug Administration

1 reference

stated in

Inxight: Drugs Database

retrieved

2 November 2018

reference URL

https://drugs.ncats.io/drug/6UXW23996M

http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf

neuroblastoma

start time

12 April 1960

approved by

Food and Drug Administration

1 reference

stated in

Inxight: Drugs Database

retrieved

2 November 2018

reference URL

https://drugs.ncats.io/drug/6UXW23996M

http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf

multiple myeloma

start time

12 April 1960

approved by

Food and Drug Administration

1 reference

stated in

Inxight: Drugs Database

retrieved

2 November 2018

reference URL

https://drugs.ncats.io/drug/6UXW23996M

http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf

ovarian cancer

start time

12 April 1960

approved by

Food and Drug Administration

1 reference

stated in

Inxight: Drugs Database

retrieved

2 November 2018

reference URL

https://drugs.ncats.io/drug/6UXW23996M

http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf

nephrotic syndrome

start time

12 April 1960

approved by

Food and Drug Administration

1 reference

stated in

Inxight: Drugs Database

retrieved

2 November 2018

reference URL

https://drugs.ncats.io/drug/6UXW23996M

http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf

chronic lymphocytic leukemia

start time

12 April 1960

approved by

Food and Drug Administration

1 reference

stated in

Inxight: Drugs Database

retrieved

2 November 2018

reference URL

https://drugs.ncats.io/drug/6UXW23996M

http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf

significant drug interaction

pentostatin

side effect

bone marrow failure

1 reference

sourcing circumstances

probably

stated in

A reference set of clinically relevant adverse drug-drug interactions

pentostatin

side effect

embolism

1 reference

sourcing circumstances

probably

stated in

A reference set of clinically relevant adverse drug-drug interactions

pentostatin

side effect

cardiotoxicity

1 reference

sourcing circumstances

probably

stated in

A reference set of clinically relevant adverse drug-drug interactions

pregnancy category

Australian pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category B

1 reference

stated in

LiverTox

retrieved

8 April 2021

reference URL

https://www.ncbi.nlm.nih.gov/books/n/livertox/Cyclophosphamide

last update

5 November 2017

subject has role

alkylating agent

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

retrieved

5 March 2018

female reproductive toxicant

start time

1 January 1989

1 reference

stated in

California Proposition 65 list of chemicals

retrieved

24 February 2020

reference URL

https://oehha.ca.gov/chemicals/cyclophosphamide-anhydrous

male reproductive toxicant

start time

1 January 1989

1 reference

stated in

California Proposition 65 list of chemicals

retrieved

25 February 2020

reference URL

https://oehha.ca.gov/chemicals/cyclophosphamide-anhydrous

developmental toxicant

start time

1 January 1989

1 reference

stated in

California Proposition 65 list of chemicals

retrieved

25 February 2020

reference URL

https://oehha.ca.gov/chemicals/cyclophosphamide-anhydrous

carcinogen

1 reference

stated in

California Proposition 65 list of chemicals

retrieved

25 February 2020

reference URL

https://oehha.ca.gov/chemicals/cyclophosphamide-anhydrous

essential medicine

0 references

related image

Cyclophosphamide iv.jpg
1,800 × 2,700; 3.65 MB

0 references

has part(s)

phosphorus

0 references

carbon

0 references

hydrogen

0 references

chlorine

0 references

nitrogen

0 references

oxygen

0 references

Commons category

Cyclophosphamide

0 references

Identifiers

InChI

InChI=1S/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)

1 reference

stated in

PubChem

PubChem CID

2907

language of work or name

English

title

cyclophosphamide (English)

retrieved

19 November 2016

InChIKey

CMSMOCZEIVJLDB-UHFFFAOYSA-N

2 references

stated in

PubChem

PubChem CID

2907

language of work or name

English

title

cyclophosphamide (English)

retrieved

19 November 2016

stated in

ChEBI release 2020-09-01

CAS Registry Number

50-18-0

2 references

stated in

Global Substance Registration System

UNII

6UXW23996M

language of work or name

English

title

cyclophosphamide anhydrous (English)

retrieved

19 November 2016

InChIKey

CMSMOCZEIVJLDB-UHFFFAOYSA-N

stated in

CAS Common Chemistry

retrieved

9 April 2021

reference URL

https://commonchemistry.cas.org/detail?cas_rn=50-18-0

ChemSpider ID

2804

1 reference

stated in

ChemSpider

ChemSpider ID

2804

language of work or name

English

title

Cyclophosphamide (English)

retrieved

19 November 2016

PubChem CID

2907

2 references

stated in

PubChem

PubChem CID

2907

language of work or name

English

title

cyclophosphamide (English)

retrieved

19 November 2016

matched by identifier from

InChIKey

InChIKey

CMSMOCZEIVJLDB-UHFFFAOYSA-N

Reaxys registry number

11744

1 reference

stated in

ChEBI

ChEBI ID

4027

language of work or name

English

title

cyclophosphamide (English)

retrieved

3 October 2016

ChEBI ID

4027

mapping relation type

exact match

2 references

stated in

ChEMBL

ChEMBL ID

CHEMBL88

language of work or name

English

title

CYCLOPHOSPHAMIDE (English)

retrieved

19 November 2016

matched by identifier from

International Chemical Identifier

InChI

InChI=1S/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)

ChEMBL ID

CHEMBL88

1 reference

stated in

ChEMBL

ChEMBL ID

CHEMBL88

language of work or name

English

title

CYCLOPHOSPHAMIDE (English)

retrieved

19 November 2016

SureChEMBL ID

SCHEMBL4346

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

InChIKey

InChIKey

CMSMOCZEIVJLDB-UHFFFAOYSA-N

UniChem compound ID

408860

1 reference

stated in

UniChem

MassBank accession ID

MSBNK-Eawag-EA257901

0 references

MSBNK-Eawag-EA257902

0 references

MSBNK-Eawag-EA257903

0 references

MSBNK-Eawag-EA257904

0 references

MSBNK-Eawag-EA257905

0 references

MSBNK-Eawag-EA257906

0 references

MSBNK-Eawag-EA257907

0 references

MSBNK-Eawag-EA257908

0 references

MSBNK-Eawag-EA257909

0 references

MSBNK-Eawag-EA257910

0 references

MSBNK-Eawag-EA257911

0 references

MSBNK-Eawag-EA257912

0 references

MSBNK-Eawag-EA257913

0 references

MSBNK-Eawag-EA257914

0 references

MSBNK-UFZ-UF411901

0 references

MSBNK-UFZ-UF411902

0 references

MSBNK-UFZ-UF411903

0 references

MSBNK-UFZ-UF411904

0 references

SPLASH

splash10-03di-0090000000-2bdfe4296c2bdf8d4a99

0 references

splash10-03di-0190000000-1e8e017f8e39fa5d73cf

0 references

splash10-0006-0930000000-d7459c8d20a8fc59f6f0

0 references

splash10-0006-0900000000-33cb20e845200f9d2618

0 references

splash10-0006-2900000000-09d33a8387b9d152f24a

0 references

splash10-01ox-6900000000-cdebe09ff6df7c25b477

0 references

splash10-03di-0090000000-d749f27c3144da2c431c

0 references

splash10-03di-0190000000-a6fa921df18384671a7c

0 references

splash10-0006-0930000000-abdb40162fc8a44200f7

0 references

splash10-0006-0900000000-8c0705ee62a5f9c7d44e

0 references

splash10-0006-2900000000-a299026342c77e92c48c

0 references

splash10-01ox-6900000000-fc2845c75bbccc83ad99

0 references

splash10-001l-0970000000-83e0f5b88b6fbe0a1ea7

0 references

splash10-0006-0900000000-5490a2b493bfde967fa3

0 references

splash10-0006-0900000000-456626f46e480e0ac670

0 references

splash10-0006-0900000000-e3ecee739b09050e915a

0 references

splash10-0006-0900000000-4cb33bb833e6cab9a106

0 references

splash10-03di-0390000000-66983035d1db7ac36bd6

0 references

splash10-0059-1490000000-36d8ebdb421248c38c7b

0 references

splash10-03di-1390000000-b8dc1a824ec33e388213

0 references

splash10-08fr-9470000000-53f4a8ff83c415492e03

0 references

NMRShiftDB structure ID

20208437

1 reference

matched by identifier from

InChIKey

InChIKey

CMSMOCZEIVJLDB-UHFFFAOYSA-N

ICSC ID

0689

0 references

CAMEO Chemicals ID

16189

0 references

ZVG number

490043

1 reference

imported from Wikimedia project

German Wikipedia

HSDB ID

3047

1 reference

stated in

Hazardous Substances Data Bank

HSDB ID

3047

publication date

28 October 2019

title

CYCLOPHOSPHAMIDE (English)

retrieved

10 May 2021

DSSTox substance ID

DTXSID5020364

2 references

stated in

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

matched by identifier from

InChIKey

InChIKey

CMSMOCZEIVJLDB-UHFFFAOYSA-N

DSSTOX compound identifier

DTXCID70364

0 references

LiverTox ID

Cyclophosphamide

0 references

NSC number

26271

0 references

EC number

200-015-4

1 reference

stated in

Global Substance Registration System

UNII

6UXW23996M

language of work or name

English

title

cyclophosphamide anhydrous (English)

retrieved

19 November 2016

ECHA Substance Infocard ID

100.000.015

1 reference

stated in

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.000.015

retrieved

27 December 2018

title

Cyclophosphamide (English)

quotation

CAS no.: 50-18-0 (English)

ATC code

L01AA01

1 reference

stated in

DrugBank

DrugBank ID

00531

language of work or name

English

title

Cyclophosphamide (English)

publication date

17 November 2015

Guide to Pharmacology Ligand ID

7154

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7154

language of work or name

English

title

cyclophosphamide (English)

retrieved

19 November 2016

MeSH descriptor ID

D003520

subject named as

Cyclophosphamide

0 references

MeSH tree code

D02.455.526.728.650.730.243

0 references

D02.705.672.500.243

0 references

RxNorm ID

1545988

1 reference

stated in

Global Substance Registration System

UNII

6UXW23996M

language of work or name

English

title

cyclophosphamide anhydrous (English)

retrieved

19 November 2016

3002

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

retrieved

26 February 2018

DrugBank ID

DB00531

1 reference

matched by identifier from

InChIKey

InChIKey

CMSMOCZEIVJLDB-UHFFFAOYSA-N

Human Metabolome Database ID

HMDB0014672

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

InChIKey

InChIKey

CMSMOCZEIVJLDB-UHFFFAOYSA-N

UNII

6UXW23996M

2 references

stated in

Global Substance Registration System

UNII

6UXW23996M

language of work or name

English

title

cyclophosphamide anhydrous (English)

retrieved

19 November 2016

matched by identifier from

InChIKey

InChIKey

CMSMOCZEIVJLDB-UHFFFAOYSA-N

MedlinePlus drug identifier

a682080

route of administration

oral administration

0 references

a611044

route of administration

intravenous injection

0 references

NDF-RT ID

N0000146452

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146452

language of work or name

English

title

CYCLOPHOSPHAMIDE (English)

retrieved

19 January 2016

Probes And Drugs ID

PD002782

0 references

DrugCentral ID

758

1 reference

stated in

UniChem

KEGG ID

C07888

1 reference

stated in

ChEBI

ChEBI ID

4027

language of work or name

English

title

cyclophosphamide (English)

retrieved

3 October 2016

D07760

1 reference

stated in

ChEBI

ChEBI ID

4027

language of work or name

English

title

cyclophosphamide (English)

retrieved

3 October 2016

IEDB Epitope ID

131782

1 reference

stated in

Immune Epitope Database and Analysis Resource

IEDB Epitope ID

131782

retrieved

1 March 2022

CA PROP 65 ID

cyclophosphamide-anhydrous

1 reference

stated in

California Proposition 65 list of chemicals

retrieved

12 December 2019

reference URL

https://oehha.ca.gov/chemicals/cyclophosphamide-anhydrous

Encyclopædia Britannica Online ID

science/cyclophosphamide

subject named as

cyclophosphamide

0 references

Freebase ID

/m/05mgqp

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

Gran Enciclopèdia Catalana ID

ciclofosfamida

0 references

Gran Enciclopèdia Catalana ID (former scheme)

0090403

0 references

Microsoft Academic ID

2776755627

0 references

OpenAlex ID

C2776755627

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

Römpp online ID

RD-03-03189

1 reference

imported from Wikimedia project

German Wikipedia

Store medisinske leksikon ID

cyklofosfamid

0 references

WikiProjectMed ID

Cyclophosphamide

0 references

WikiSkripta article ID

55569

0 references

 

Sitelinks

Wikipedia(38 entries)

edit

• arwiki سيكلوفوسفاميد
• azbwiki سیکلوفسفامید
• cawiki Ciclofosfamida
• cswiki Cyklofosfamid
• cywiki Cycloffosffamid
• dewiki Cyclophosphamid
• elwiki Κυκλοφωσφαμίδη
• enwiki Cyclophosphamide
• eswiki Ciclofosfamida
• fawiki سیکلوفسفامید
• fiwiki Syklofosfamidi
• frwiki Cyclophosphamide
• gawiki Cioglafosfaimíd
• glwiki Ciclofosfamida
• huwiki Ciklofoszfamid
• hywiki Ցիկլոֆոսֆամիդ
• idwiki Siklofosfamid
• itwiki Ciclofosfamide
• jawiki シクロホスファミド
• kowiki 시클로포스파미드
• mlwiki സൈക്ലോഫോസ്ഫാമൈഡ്
• nlwiki Cyclofosfamide
• orwiki ସାଇକ୍ଲୋଫସଫାମାଇଡ
• plwiki Cyklofosfamid
• pswiki سايکلوفوسفمايډ
• ptwiki Ciclofosfamida
• rowiki Ciclofosfamidă
• ruwiki Циклофосфамид
• shwiki Ciklofosfamid
• simplewiki Cyclophosphamide
• slwiki Ciklofosfamid
• srwiki Ciklofosfamid
• svwiki Cyklofosfamid
• tlwiki Cyclophosphamide
• trwiki Siklofosfamid
• ukwiki Циклофосфамід
• viwiki Cyclophosphamide
• zhwiki 环磷酰胺

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• commonswiki Category:Cyclophosphamide

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