Major histocompatibility complex, class II, DR beta 4 (Q5630193)

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mammalian protein found in Homo sapiens

• HLA-DRB4
• major histocompatibility complex, class II, DR beta 4
• MHC class II antigen DRB4
• HLA class II histocompatibility antigen, DR beta 4 chain

edit

Language	Label	Description	Also known as
English	Major histocompatibility complex, class II, DR beta 4	mammalian protein found in Homo sapiens	HLA-DRB4 major histocompatibility complex, class II, DR beta 4 MHC class II antigen DRB4 HLA class II histocompatibility antigen, DR beta 4 chain

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13762

part of

Immunoglobulin-like fold

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13762

Immunoglobulin-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13762

MHC classes I/II-like antigen recognition protein

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13762

MHC class II, alpha/beta chain, N-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13762

MHC class II, beta chain, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin C1-set, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin/major histocompatibility complex, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13762

encoded by

HLA-DRB4

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13762

cell component

integral component of membrane

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

endocytic vesicle membrane

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

TAS

clathrin-coated endocytic vesicle membrane

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

TAS

endosome

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

Golgi apparatus

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

trans-Golgi network membrane

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

TAS

endoplasmic reticulum membrane

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

membrane

determination method or standard

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

late endosome membrane

determination method or standard

IDA

IEA

3 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

retrieved

9 May 2019

stated in

MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IDA

retrieved

9 May 2019

stated in

The HLA-DRalpha chain is modified by polyubiquitination

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IDA

Golgi membrane

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

TAS

plasma membrane

determination method or standard

TAS

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

TAS

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

transport vesicle membrane

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

TAS

MHC class II protein complex

determination method or standard

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

lysosomal membrane

determination method or standard

IDA

TAS

IEA

3 references

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

TAS

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

retrieved

9 May 2019

stated in

MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IDA

endoplasmic reticulum

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

ER to Golgi transport vesicle membrane

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

TAS

lysosome

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

integral component of lumenal side of endoplasmic reticulum membrane

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

TAS

endosome membrane

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

biological process

antigen processing and presentation

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

antigen processing and presentation of exogenous peptide antigen via MHC class II

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

TAS

interferon-gamma-mediated signaling pathway

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

TAS

immune system process

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

immune response

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

T cell receptor signaling pathway

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

TAS

adaptive immune response

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13762

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13762

determination method or standard

IEA

has part(s)

MHC class II, beta chain, N-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13762

immunoglobulin C1-set

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13762

immunoglobulin-like domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13762

Immunoglobulin/major histocompatibility complex, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13762

Identifiers

MeSH descriptor ID

D059845

subject named as

HLA-DRB4 Chains

0 references

MeSH tree code

D09.400.430.890.509.400.440.200.040

0 references

D12.776.395.550.509.400.440.200.040

0 references

D12.776.543.550.440.400.440.200.040

0 references

D23.050.301.500.400.400.440.200.040

0 references

D23.050.301.500.450.400.440.333.875

0 references

D23.050.705.552.410.400.440.200.040

0 references

D23.050.705.552.450.400.440.333.875

0 references

RefSeq protein ID

NP_068818

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

3126

UniProt protein ID

P13762

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13762

Ensembl protein ID

ENSP00000410857

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000410857

ENSP00000410046

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000410046

ENSP00000412031

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000412031

UMLS CUI

C0173809

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

edit

Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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