FDU-NNE1

FDU-NNE1
Legal status
Legal status	CA: Schedule II; DE: NpSG (Industrial and scientific use only); UK: Class B;
Identifiers
	IUPAC name [1-(4-fluorobenzyl)-N-(naphthalen-1-yl)-1H-indole-3-carboxamide;
CAS Number	2365471-76-5;
PubChem CID	122213806;
ChemSpider	58794744;
UNII	M5H92FEG4W;
Chemical and physical data
Formula	C26H19FN2O
Molar mass	394.449 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(C1=CN(CC2=CC=C(F)C=C2)C3=C1C=CC=C3)NC4=C(C=CC=C5)C5=CC=C4;
	InChI InChI=1S/C26H19FN2O/c27-20-14-12-18(13-15-20)16-29-17-23(22-9-3-4-11-25(22)29)26(30)28-24-10-5-7-19-6-1-2-8-21(19)24/h1-15,17H,16H2,(H,28,30); Key:XYSIFMHZXZATQO-UHFFFAOYSA-N;

FDU-NNE1 (also known as FDU-NNEI and FDU-MN-24) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB₁ receptor and has been sold online as a designer drug.^[1]^[2] Given the known metabolic liberation (and presence as an impurity) of amantadine in the related compound APINACA, it is suspected that metabolic hydrolysis of the amide group of FDU-NNE1 will release 1-naphthylamine, a known carcinogen.

References

^ "FDU-NNEI". Cayman Chemical. Retrieved 23 July 2015.
^ Uchiyama N, Shimokawa Y, Kikura-Hanajiri R, Demizu Y, Goda Y, Hakamatsuka T (February 2015). "N-OH-EDMA, and a cathinone derivative dimethoxy-α-PHP, newly identified in illegal products". Forensic Toxicology. 33 (2): 244–259. doi:10.1007/s11419-015-0268-7. PMC 4525202. PMID 26257833.

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[1] "FDU-NNEI". Cayman Chemical. Retrieved 23 July 2015.

[Uchiyama_2015-2] Uchiyama N, Shimokawa Y, Kikura-Hanajiri R, Demizu Y, Goda Y, Hakamatsuka T (February 2015). "N-OH-EDMA, and a cathinone derivative dimethoxy-α-PHP, newly identified in illegal products". Forensic Toxicology. 33 (2): 244–259. doi:10.1007/s11419-015-0268-7. PMC 4525202. PMID 26257833.

[1]

[2]

See also

References