I have, and thats not good, because it brings me a little bit too far into the story. From what i can see, my old saves were some quests before this new entry point, not too far, but far enough to miss out of some seemingly crucial story events (and there is a girl available, Neon, which i do not recognize).
So if i cannot get the savegame running, i pretty much have to restart from scratch, just to not miss out on some important story parts :/
And ignoring that error just doesn´t work, like the other user already mentioned.