itch.io

I think early to mid late game area dice are the way to go, but very late game I think the best dice hand is
-Gold Grow Block & Heal
-Gold Grow Block & Attack
-Silver Block & Boost
-Hollow Mirror
-Hollow Mirror

This allows for ~6 dice worth of effective health each turn. Worst case first turn is 27 shield (3 on both Grow Block dice and 3 on the Block & Boost die) and best case first turn is 34 shield (5 on both Grow Block dice and 2 on the Block & Boost die). 

I can't make assumptions about the average performance because of different face distributions, but I can estimate the average effective health gain to be ~6(n-1)+40 on turn n. (This includes actual hp gained, if you're at max health it will be less).

I would say a good estimate for health is ~80 when you acquire the hand. This would let you survive until the enemies can output ~60-70(?) damage per turn. The strategy would be to outlast+attack enemies until one is left, stop attacking and heal to full, and then kill the last one to move on to the next floor. Bosses are basically the same.