Domen HEAT ponavljanja

Dostupne proteinske strukture:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

HEAT ponavljanje
HEAT ponavljanje
	Struktura proteina fosfataza 2A, PR65/A podjedinice sadrži 15 ponavljanja HEAT motiva.
Identifikatori
Simbol	HEAT
Pfam	PF02985
InterPro	IPR000357
PROSITE	PDOC50077
SCOP	1b3u
SUPERFAMILY	1b3u
Pfam
Dostupne proteinske strukture:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Domen HEAT ponavljanja je proteinski domen prisutan u brojnim citoplazmatičnim proteinima uključujući četiri po kojima je formira akronim HEAT (Hantingtin, elongacioni faktor 3 (EF3), proteinska fosfataza 2A (PP2A), i kvašćana kinaza TOR1).^[2] HEAT ponavljanja formiraju štapićaste heliksne strukture koje učestvuju u intraćelijskom transportu.

Reference

^ Groves MR, Hanlon N, Turowski P, Hemmings BA, Barford D (1999). „The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs”. Cell. 96 (1): 99—110. PMID 9989501. doi:10.1016/S0092-8674(00)80963-0.
^ Andrade MA, Bork P (1995). „HEAT repeats in the Huntington's disease protein”. Nat. Genet. 11 (2): 115—6. PMID 7550332. doi:10.1038/ng1095-115.

[pmid9989501-1] Groves MR, Hanlon N, Turowski P, Hemmings BA, Barford D (1999). „The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs”. Cell. 96 (1): 99—110. PMID 9989501. doi:10.1016/S0092-8674(00)80963-0.

[pmid7550332-2] Andrade MA, Bork P (1995). „HEAT repeats in the Huntington's disease protein”. Nat. Genet. 11 (2): 115—6. PMID 7550332. doi:10.1038/ng1095-115.

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