TCR-induced sumoylation of the kinase PKC-θ controls T cell synapse organization and T cell activation. (Q45941366)

18 December 2017

title

TCR-induced sumoylation of the kinase PKC-θ controls T cell synapse organization and T cell activation. (English)

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18 December 2017

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Liang-Hui Diao

8

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Xu-Dong Wang

object named as

Xu-Dong Wang

1

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author name string

Yu Gong

2

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18 December 2017

Zhi-Long Chen

3

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18 December 2017

Bei-Ni Gong

4

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18 December 2017

Ji-Ji Xie

5

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18 December 2017

Chuan-Qi Zhong

6

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18 December 2017

Qi-Long Wang

7

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18 December 2017

Anlong Xu

9

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18 December 2017

Jiahuai Han

10

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18 December 2017

Amnon Altman

11

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18 December 2017

Yingqiu Li

12

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18 December 2017

language of work or name

English

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publication date

21 September 2015

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18 December 2017

published in

Nature Immunology

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18 December 2017

volume

16

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18 December 2017

issue

11

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18 December 2017

page(s)

1195-1203

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18 December 2017

https://scigraph.springernature.com/pub.10.1038/ni.3259

exact match

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cites work

Protein modification by SUMO

1 reference

Concepts in sumoylation: a decade on

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1 reference

Sumoylation: a regulatory protein modification in health and disease

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Summon SUMO to wrestle with inflammation

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The yin and yang of protein kinase C-theta (PKCθ): a novel drug target for selective immunosuppression

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Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes

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1 reference

Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta

21 January 2018

1 reference

Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells

21 January 2018

1 reference

Protein kinase C-theta mediates negative feedback on regulatory T cell function

21 January 2018

1 reference

Three-dimensional segregation of supramolecular activation clusters in T cells

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1 reference

Functional anatomy of T cell activation and synapse formation

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1 reference

Staging and resetting T cell activation in SMACs

21 January 2018

1 reference

Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation

21 January 2018

1 reference

Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation

21 January 2018

1 reference

Filamin A is required for T cell activation mediated by protein kinase C-theta.

21 January 2018

1 reference

CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse

21 January 2018

1 reference

Critical role of novel Thr-219 autophosphorylation for the cellular function of PKCtheta in T lymphocytes.

21 January 2018

1 reference

A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28

21 January 2018

1 reference

SUMOylation and De-SUMOylation: wrestling with life's processes

21 January 2018

1 reference

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

1 reference

A method of mapping protein sumoylation sites by mass spectrometry using a modified small ubiquitin-like modifier 1 (SUMO-1) and a computational program.

21 January 2018

1 reference

Nuclear and unclear functions of SUMO

21 January 2018

1 reference

Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses

21 January 2018

1 reference

A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells

21 January 2018

1 reference

Regulation of gene-activation pathways by PIAS proteins in the immune system

21 January 2018

1 reference

The immunological synapse: a molecular machine controlling T cell activation

21 January 2018

1 reference

An active kinase domain is required for retention of PKCθ at the T cell immunological synapse.

21 January 2018

1 reference

Filamin A mediates interactions between cytoskeletal proteins that control cell adhesion

21 January 2018

1 reference

Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT.

21 January 2018

1 reference

Immunity by ubiquitylation: a reversible process of modification

21 January 2018

1 reference

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

21 January 2018

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Unconventional post-translational modifications in immunological signaling

21 January 2018

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N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca²⁺ signaling

21 January 2018

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21 January 2018

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T cell antigen receptor activation and actin cytoskeleton remodeling

21 January 2018

1 reference

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells

21 January 2018

1 reference

The fast-growing business of SUMO chains

21 January 2018

1 reference

Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster

21 January 2018

1 reference

Mutual interactions between the SUMO and ubiquitin systems: a plea of no contest

21 January 2018

1 reference

SUMOylation of the GTPase Rac1 is required for optimal cell migration

21 January 2018

1 reference

SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane

21 January 2018

1 reference

Hunter to gatherer and back: immunological synapses and kinapses as variations on the theme of amoeboid locomotion

21 January 2018

1 reference

Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics

21 January 2018

1 reference

CD28 interaction with filamin-A controls lipid raft accumulation at the T-cell immunological synapse

21 January 2018

1 reference

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

21 January 2018

1 reference

Dynein-Driven Transport of T Cell Receptor Microclusters Regulates Immune Synapse Formation and T Cell Activation

21 January 2018

1 reference

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

Differential regulation of Th2 and Th1 lung inflammatory responses by protein kinase C theta

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26390157

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26390157

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.3259

1 reference

18 December 2017

Dimensions Publication ID

1029023837

0 references

1 reference

18 December 2017