ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin. (Q45993642)

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scientific article published on 27 May 2009

Language	Label	Description	Also known as
English	ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin.	scientific article published on 27 May 2009

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin. (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

pharmacokinetics

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based on heuristic

inferred from title

2

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

Pertti J. Neuvonen

5

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

6

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

author name string

J E Keskitalo

1

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

M F Fromm

3

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

K J Kurkinen

4

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

language of work or name

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publication date

27 May 2009

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

Clinical Pharmacology & Therapeutics

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

86

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PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

2

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

197-203

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

SLCO1B1 variants and statin-induced myopathy--a genomewide study

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The emerging pharmacotherapeutic significance of the breast cancer resistance protein (ABCG2).

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ATP-dependent transport of rosuvastatin in membrane vesicles expressing breast cancer resistance protein

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Involvement of multiple transporters in the hepatobiliary transport of rosuvastatin

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Functional analysis of SNPs variants of BCRP/ABCG2.

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Single nucleotide polymorphisms modify the transporter activity of ABCG2.

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Re-evaluation and functional classification of non-synonymous single nucleotide polymorphisms of the human ATP-binding cassette transporter ABCG2.

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Single nucleotide polymorphisms result in impaired membrane localization and reduced atpase activity in multidrug transporter ABCG2.

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Pharmacogenetic characterization of sulfasalazine disposition based on NAT2 and ABCG2 (BCRP) gene polymorphisms in humans

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Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males

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ABCB1 haplotypes differentially affect the pharmacokinetics of the acid and lactone forms of simvastatin and atorvastatin.

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Polymorphisms in the multidrug resistance-1 (MDR1) gene influence the response to atorvastatin treatment in a gender-specific manner

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The role of common variants of ABCB1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and safety of simvastatin treatment

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Importance of P-glycoprotein at blood-tissue barriers

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Statin-associated myopathy

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Exposure of atorvastatin is unchanged but lactone and acid metabolites are increased several-fold in patients with atorvastatin-induced myopathy

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SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers

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Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants

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Evaluation of inhibitory drug interactions during drug development: genetic polymorphisms must be considered

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Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver

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Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

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Pharmacogenetics of cyclosporine in children suggests an age-dependent influence of ABCB1 polymorphisms

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Lipid-lowering response to statins is affected by CYP3A5 polymorphism

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Multidrug resistance gene G1199A polymorphism alters efflux transport activity of P-glycoprotein

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Determination of atorvastatin and metabolites in human plasma with solid-phase extraction followed by LC-tandem MS.

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Quantification of rosuvastatin in human plasma by automated solid-phase extraction using tandem mass spectrometric detection

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ATP-binding cassette transporters in human heart failure

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Characterization of beta-adrenoceptor antagonists as substrates and inhibitors of the drug transporter P-glycoprotein

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21 January 2018

SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid

1 reference

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21 January 2018

Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics of Atorvastatin and Rosuvastatin

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SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin

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Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population

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Pharmacogenomics of MRP transporters (ABCC1-5) and BCRP (ABCG2)

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7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CLPT.2009.79

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19474787

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