SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers (Q34579035)

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English	SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 August 2017

SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

pharmacokinetics

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author name string

I Ieiri

1

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Europe PubMed Central

PubMed publication ID

3 August 2017

S Suwannakul

2

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Europe PubMed Central

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3 August 2017

K Maeda

3

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Europe PubMed Central

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3 August 2017

H Uchimaru

4

1 reference

Europe PubMed Central

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3 August 2017

K Hashimoto

5

1 reference

Europe PubMed Central

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3 August 2017

M Kimura

6

1 reference

Europe PubMed Central

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3 August 2017

H Fujino

7

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

M Hirano

8

1 reference

Europe PubMed Central

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3 August 2017

H Kusuhara

9

1 reference

Europe PubMed Central

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3 August 2017

S Irie

10

1 reference

Europe PubMed Central

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3 August 2017

S Higuchi

11

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3 August 2017

Y Sugiyama

12

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3 August 2017

language of work or name

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publication date

25 April 2007

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3 August 2017

Clinical Pharmacology & Therapeutics

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3 August 2017

82

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3 August 2017

5

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Europe PubMed Central

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3 August 2017

541-547

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Europe PubMed Central

PubMed publication ID

3 August 2017

Metabolic properties of the acid and lactone forms of HMG-CoA reductase inhibitors

1 reference

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Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization

1 reference

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Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: similarities and difference in the metabolism of pitavastatin in monkeys and humans

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Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans

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The superfamily of organic anion transporting polypeptides

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A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters

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Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin

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Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans

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Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

1 reference

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High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

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Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics

1 reference

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Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers.

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Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1)

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Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics

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Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril

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Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.

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Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8

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Genetic variation in the ATP-binding Cassette Transporter gene ABCG2 (BCRP) in a Swedish population

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Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype

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Functional analysis of SNPs variants of BCRP/ABCG2.

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Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males

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Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells

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Effect of genetic polymorphism of OATP-C (SLCO1B1) on lipid-lowering response to HMG-CoA reductase inhibitors

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SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid

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Exposure of atorvastatin is unchanged but lactone and acid metabolites are increased several-fold in patients with atorvastatin-induced myopathy

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10.1038/SJ.CLPT.6100190

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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