Latest revision | Your text |
label / es | label / es |
| Cinasa Jano 1
|
label / sl | label / sl |
| Janusova kinaza 1
|
aliases / es / 0 | aliases / es / 0 |
| JAK1
|
description / nl | description / nl |
| proteïne in Janus kinase 1 | | proteïne |
description / ar | description / ar |
| بروتين في الإنسان العاقل | | بروتين |
description / id | description / id |
| protein
|
description / ace | description / ace |
| protèin
|
description / de | description / de |
| Protein in Homo sapiens
|
description / sv | description / sv |
| protein
|
description / es | description / es |
| proteína encontrada en Homo sapiens
|
description / uk | description / uk |
| білок людини
|
| Property / UniProt protein ID: P23458 / reference |
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Property / UniProt protein ID: P23458 / reference | |
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| Property / Ensembl protein ID: ENSP00000343204 / reference |
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Property / Ensembl protein ID: ENSP00000343204 / reference | |
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| Property / encoded by: JAK1 / reference |
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Property / encoded by: JAK1 / reference | |
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| Property / biological process: intracellular signal transduction / reference |
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| Property / biological process: intracellular signal transduction / reference |
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Property / biological process: intracellular signal transduction / reference | |
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Property / biological process: intracellular signal transduction / reference | |
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| Property / biological process: phosphorylation / reference |
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Property / biological process: phosphorylation / reference | |
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| Property / biological process: interferon-gamma-mediated signaling pathway / reference |
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Property / biological process: interferon-gamma-mediated signaling pathway / reference | |
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| Property / biological process: response to antibiotic / reference |
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Property / biological process: response to antibiotic / reference | |
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| Property / biological process: MAPK cascade / reference |
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Property / biological process: MAPK cascade / reference | |
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| Property / biological process: positive regulation of sprouting angiogenesis / reference |
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Property / biological process: positive regulation of sprouting angiogenesis / reference | |
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| Property / biological process: protein phosphorylation / reference |
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| Property / biological process: protein phosphorylation / reference |
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Property / biological process: protein phosphorylation / reference | |
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Property / biological process: protein phosphorylation / reference | |
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| Property / biological process: regulation of interferon-gamma-mediated signaling pathway / reference |
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Property / biological process: regulation of interferon-gamma-mediated signaling pathway / reference | |
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| Property / biological process: type I interferon signaling pathway / reference |
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Property / biological process: type I interferon signaling pathway / reference | |
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Property / biological process | Property / biological process |
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Property / biological process | Property / biological process |
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| Property / biological process: interleukin-12-mediated signaling pathway / reference |
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Property / biological process: interleukin-12-mediated signaling pathway / reference | |
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| Property / biological process: interleukin-7-mediated signaling pathway / reference |
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Property / biological process: interleukin-7-mediated signaling pathway / reference | |
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| Property / biological process: interleukin-15-mediated signaling pathway / reference |
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Property / biological process: interleukin-15-mediated signaling pathway / reference | |
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| Property / biological process: interleukin-9-mediated signaling pathway / reference |
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Property / biological process: interleukin-9-mediated signaling pathway / reference | |
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Property / biological process | |
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Property / biological process: peptidyl-tyrosine phosphorylation / rank | |
| Normal rank
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Property / biological process: peptidyl-tyrosine phosphorylation / qualifier | |
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Property / biological process: peptidyl-tyrosine phosphorylation / reference | |
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Property / biological process | |
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Property / biological process: cytokine-mediated signaling pathway / rank | |
| Normal rank
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Property / biological process: cytokine-mediated signaling pathway / qualifier | |
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Property / biological process: cytokine-mediated signaling pathway / qualifier | |
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Property / biological process: cytokine-mediated signaling pathway / reference | |
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Property / biological process: cytokine-mediated signaling pathway / reference | |
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Property / biological process | |
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Property / biological process: interleukin-2-mediated signaling pathway / rank | |
| Normal rank
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Property / biological process: interleukin-2-mediated signaling pathway / qualifier | |
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Property / biological process: interleukin-2-mediated signaling pathway / qualifier | |
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Property / biological process: interleukin-2-mediated signaling pathway / reference | |
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Property / biological process: interleukin-2-mediated signaling pathway / reference | |
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Property / biological process | |
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Property / biological process: interleukin-21-mediated signaling pathway / rank | |
| Normal rank
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Property / biological process: interleukin-21-mediated signaling pathway / qualifier | |
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Property / biological process: interleukin-21-mediated signaling pathway / reference | |
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Property / biological process | |
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Property / biological process: interleukin-6-mediated signaling pathway / rank | |
| Normal rank
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Property / biological process: interleukin-6-mediated signaling pathway / qualifier | |
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Property / biological process: interleukin-6-mediated signaling pathway / reference | |
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Property / biological process | |
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Property / biological process: interleukin-27-mediated signaling pathway / rank | |
| Normal rank
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Property / biological process: interleukin-27-mediated signaling pathway / qualifier | |
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Property / biological process: interleukin-27-mediated signaling pathway / reference | |
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Property / biological process | |
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Property / biological process: interleukin-35-mediated signaling pathway / rank | |
| Normal rank
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Property / biological process: interleukin-35-mediated signaling pathway / qualifier | |
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Property / biological process: interleukin-35-mediated signaling pathway / reference | |
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| Property / molecular function: transferase activity / reference |
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Property / molecular function: transferase activity / reference | |
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| Property / molecular function: nucleotide binding / reference |
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Property / molecular function: nucleotide binding / reference | |
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| Property / molecular function: protein kinase activity / reference |
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Property / molecular function: protein kinase activity / reference | |
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| Property / molecular function: CCR5 chemokine receptor binding / reference |
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Property / molecular function: CCR5 chemokine receptor binding / reference | |
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| Property / molecular function: metal ion binding / reference |
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Property / molecular function: metal ion binding / reference | |
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| Property / molecular function: kinase activity / reference |
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Property / molecular function: kinase activity / reference | |
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| Property / molecular function: protein binding / reference |
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| Property / molecular function: protein binding / reference |
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| Property / molecular function: protein binding / reference |
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| Property / molecular function: protein binding / reference |
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| Property / molecular function: protein binding / reference |
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Property / molecular function: protein binding / reference | |
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Property / molecular function: protein binding / reference | |
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Property / molecular function: protein binding / reference | |
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Property / molecular function: protein binding / reference | |
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Property / molecular function: protein binding / reference | |
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| Property / molecular function: protein tyrosine kinase activity / reference |
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| Property / molecular function: protein tyrosine kinase activity / reference |
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| Property / molecular function: protein tyrosine kinase activity / reference |
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| Property / molecular function: protein tyrosine kinase activity / reference |
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| Property / molecular function: protein tyrosine kinase activity / reference |
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| Property / molecular function: protein tyrosine kinase activity / reference |
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| Property / molecular function: protein tyrosine kinase activity / reference |
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| Property / molecular function: protein tyrosine kinase activity / reference |
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Property / molecular function: protein tyrosine kinase activity / reference | |
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Property / molecular function: protein tyrosine kinase activity / reference | |
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Property / molecular function: protein tyrosine kinase activity / reference | |
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Property / molecular function: protein tyrosine kinase activity / reference | |
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Property / molecular function: protein tyrosine kinase activity / reference | |
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Property / molecular function: protein tyrosine kinase activity / reference | |
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Property / molecular function: protein tyrosine kinase activity / reference | |
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| Property / molecular function: protein phosphatase binding / reference |
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Property / molecular function: protein phosphatase binding / reference | |
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| Property / molecular function: ATP binding / reference |
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| Property / molecular function: ATP binding / reference |
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Property / molecular function: ATP binding / reference | |
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Property / molecular function: ATP binding / reference | |
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| Property / molecular function: ubiquitin protein ligase binding / reference |
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Property / molecular function: ubiquitin protein ligase binding / reference | |
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Property / molecular function | |
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Property / molecular function: non-membrane spanning protein tyrosine kinase activity / rank | |
| Normal rank
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Property / molecular function: non-membrane spanning protein tyrosine kinase activity / qualifier | |
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Property / molecular function: non-membrane spanning protein tyrosine kinase activity / qualifier | |
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Property / molecular function: non-membrane spanning protein tyrosine kinase activity / reference | |
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Property / molecular function: non-membrane spanning protein tyrosine kinase activity / reference | |
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Property / molecular function: non-membrane spanning protein tyrosine kinase activity / reference | |
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Property / molecular function | |
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Property / molecular function: growth hormone receptor binding / rank | |
| Normal rank
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Property / molecular function: growth hormone receptor binding / qualifier | |
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Property / molecular function: growth hormone receptor binding / qualifier | |
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Property / molecular function: growth hormone receptor binding / qualifier | |
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Property / molecular function: growth hormone receptor binding / reference | |
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Property / molecular function: growth hormone receptor binding / reference | |
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Property / molecular function: growth hormone receptor binding / reference | |
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| Property / cell component: cytoplasm / reference |
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Property / cell component: cytoplasm / reference | |
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| Property / cell component: cytosol / reference |
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Property / cell component: cytosol / reference | |
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| Property / cell component: membrane / reference |
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| Property / cell component: membrane / reference |
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Property / cell component: membrane / reference | |
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Property / cell component: membrane / reference | |
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| Property / cell component: cytoskeleton / reference |
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Property / cell component: cytoskeleton / reference | |
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| Property / cell component: endomembrane system / reference |
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Property / cell component: endomembrane system / reference | |
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| Property / cell component: nucleus / reference |
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Property / cell component: nucleus / reference | |
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| Property / cell component: endosome / reference |
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Property / cell component: endosome / reference | |
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Property / cell component | |
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Property / cell component: focal adhesion / rank | |
| Normal rank
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Property / cell component: focal adhesion / qualifier | |
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Property / cell component: focal adhesion / reference | |
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Property / physically interacts with | |
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Property / physically interacts with: baricitinib / rank | |
| Normal rank
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Property / physically interacts with: baricitinib / qualifier | |
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Property / physically interacts with: baricitinib / reference | |
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Property / physically interacts with | |
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Property / physically interacts with: momelotinib / rank | |
| Normal rank
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Property / physically interacts with: momelotinib / qualifier | |
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Property / physically interacts with: momelotinib / reference | |
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Property / physically interacts with | |
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Property / physically interacts with: pacritinib / rank | |
| Normal rank
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Property / physically interacts with: pacritinib / qualifier | |
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Property / physically interacts with: pacritinib / reference | |
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Property / physically interacts with | |
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Property / physically interacts with: ruxolitinib / rank | |
| Normal rank
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Property / physically interacts with: ruxolitinib / qualifier | |
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Property / physically interacts with: ruxolitinib / reference | |
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Property / physically interacts with | |
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Property / physically interacts with: filgotinib / rank | |
| Normal rank
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Property / physically interacts with: filgotinib / qualifier | |
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Property / physically interacts with: filgotinib / reference | |
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Property / physically interacts with | |
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Property / physically interacts with: momelotinib / rank | |
| Normal rank
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Property / physically interacts with: momelotinib / qualifier | |
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Property / physically interacts with: momelotinib / reference | |
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Property / physically interacts with | |
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Property / physically interacts with: upadacitinib / rank | |
| Normal rank
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Property / physically interacts with: upadacitinib / qualifier | |
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Property / physically interacts with: upadacitinib / reference | |
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Property / physically interacts with | |
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Property / physically interacts with: peficitinib / rank | |
| Normal rank
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Property / physically interacts with: peficitinib / qualifier | |
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Property / physically interacts with: peficitinib / reference | |
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| Property / has part(s): tyrosine-protein kinase, active site / reference |
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Property / has part(s): tyrosine-protein kinase, active site / reference | |
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| Property / has part(s): protein kinase, ATP binding site / reference |
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Property / has part(s): protein kinase, ATP binding site / reference | |
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| Property / has part(s): protein kinase domain / reference |
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Property / has part(s): protein kinase domain / reference | |
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| Property / has part(s): tyrosine-protein kinase, catalytic domain / reference |
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Property / has part(s): tyrosine-protein kinase, catalytic domain / reference | |
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| Property / has part(s): SH2 domain / reference |
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Property / has part(s): SH2 domain / reference | |
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| Property / has part(s): serine-threonine/tyrosine-protein kinase, catalytic domain / reference |
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Property / has part(s): serine-threonine/tyrosine-protein kinase, catalytic domain / reference | |
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| Property / has part(s): Band 4.1 domain / reference |
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Property / has part(s): Band 4.1 domain / reference | |
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| Property / has part(s): FERM central domain / reference |
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Property / has part(s): FERM central domain / reference | |
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| Property / has part(s): FERM domain / reference |
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Property / has part(s): FERM domain / reference | |
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| Property / found in taxon: Homo sapiens / reference |
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Property / found in taxon: Homo sapiens / reference | |
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| Property / RefSeq protein ID: NP_001307852 / reference |
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Property / RefSeq protein ID: NP_001307852 / reference | |
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| Property / RefSeq protein ID: NP_001308781 / reference |
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Property / RefSeq protein ID: NP_001308781 / reference | |
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| Property / RefSeq protein ID: NP_001308782 / reference |
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Property / RefSeq protein ID: NP_001308782 / reference | |
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| Property / RefSeq protein ID: NP_001308783 / reference |
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Property / RefSeq protein ID: NP_001308783 / reference | |
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| Property / RefSeq protein ID: NP_001308784 / reference |
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Property / RefSeq protein ID: NP_001308784 / reference | |
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| Property / RefSeq protein ID: NP_001308785 / reference |
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Property / RefSeq protein ID: NP_001308785 / reference | |
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| Property / RefSeq protein ID: NP_001308786 / reference |
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Property / RefSeq protein ID: NP_001308786 / reference | |
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| Property / RefSeq protein ID: NP_002218 / reference |
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Property / RefSeq protein ID: NP_002218 / reference | |
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| Property / instance of: protein / reference |
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Property / instance of: protein / reference | |
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| Property / part of: tyrosine-protein kinase, non-receptor Jak1 / reference |
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Property / part of: tyrosine-protein kinase, non-receptor Jak1 / reference | |
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| Property / part of: Protein kinase-like domain superfamily / reference |
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Property / part of: Protein kinase-like domain superfamily / reference | |
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| Property / part of: SH2 domain superfamily / reference |
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Property / part of: SH2 domain superfamily / reference | |
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| Property / part of: FERM superfamily, second domain / reference |
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Property / part of: FERM superfamily, second domain / reference | |
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Property / part of | |
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Property / part of: Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family / rank | |
| Normal rank
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Property / part of: Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family / reference | |
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Property / part of | |
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Property / part of: SH2 domain, protein family / rank | |
| Normal rank
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Property / part of: SH2 domain, protein family / reference | |
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Property / part of | |
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Property / part of: Band 4.1 domain, protein family / rank | |
| Normal rank
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Property / part of: Band 4.1 domain, protein family / reference | |
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Property / part of | |
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Property / part of: FERM central domain, protein family / rank | |
| Normal rank
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Property / part of: FERM central domain, protein family / reference | |
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Property / part of | |
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Property / part of: FERM domain, protein family / rank | |
| Normal rank
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Property / part of: FERM domain, protein family / reference | |
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Property / part of | |
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Property / part of: Protein kinase domain, protein family / rank | |
| Normal rank
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Property / part of: Protein kinase domain, protein family / reference | |
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Property / part of | |
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Property / part of: Protein kinase, ATP binding site, protein family / rank | |
| Normal rank
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Property / part of: Protein kinase, ATP binding site, protein family / reference | |
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Property / part of | |
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Property / part of: Tyrosine-protein kinase, catalytic domain, protein family / rank | |
| Normal rank
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Property / part of: Tyrosine-protein kinase, catalytic domain, protein family / reference | |
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Property / part of | |
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Property / part of: Tyrosine-protein kinase, active site, protein family / rank | |
| Normal rank
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Property / part of: Tyrosine-protein kinase, active site, protein family / reference | |
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Property / MeSH descriptor ID | |
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Property / MeSH descriptor ID: D053613 / rank | |
| Normal rank
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Property / MeSH descriptor ID: D053613 / qualifier | |
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Property / MeSH tree code | |
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Property / MeSH tree code: D12.776.476.568.124.100 / rank | |
| Normal rank
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Property / MeSH tree code | |
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Property / MeSH tree code: D08.811.913.696.620.682.725.124.100 / rank | |
| Normal rank
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Property / UMLS CUI | |
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Property / UMLS CUI: C0169658 / rank | |
| Normal rank
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Property / UMLS CUI: C0169658 / reference | |
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| Property / subclass of |
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| Property / subclass of: protein / rank |
| | Normal rank |
| Property / subclass of: protein / reference |
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| Property / molecular function |
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| Property / molecular function: guanyl-nucleotide exchange factor activity / rank |
| | Normal rank |
| Property / molecular function: guanyl-nucleotide exchange factor activity / qualifier |
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| Property / molecular function: guanyl-nucleotide exchange factor activity / reference |
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| Property / physically interacts with |
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| Property / physically interacts with: baricitinib / rank |
| | Normal rank |
| Property / physically interacts with: baricitinib / qualifier |
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| Property / physically interacts with: baricitinib / reference |
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| Property / physically interacts with |
| | |
| Property / physically interacts with: momelotinib / rank |
| | Normal rank |
| Property / physically interacts with: momelotinib / qualifier |
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| Property / physically interacts with: momelotinib / reference |
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| Property / physically interacts with |
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| Property / physically interacts with: pacritinib / rank |
| | Normal rank |
| Property / physically interacts with: pacritinib / qualifier |
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| Property / physically interacts with: pacritinib / reference |
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| Property / physically interacts with |
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| Property / physically interacts with: ruxolitinib / rank |
| | Normal rank |
| Property / physically interacts with: ruxolitinib / qualifier |
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| Property / physically interacts with: ruxolitinib / reference |
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