Lectin, mannose binding 1 (Q21103045)

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mammalian protein found in Homo sapiens

ER-Golgi intermediate compartment 53 kDa protein
Gp58
endoplasmic reticulum-golgi intermediate compartment protein 53
LMAN1
Lectin mannose-binding 1
protein ERGIC-53
intracellular mannose-specific lectin MR60

Language	Label	Description	Also known as
English	Lectin, mannose binding 1	mammalian protein found in Homo sapiens	ER-Golgi intermediate compartment 53 kDa protein Gp58 endoplasmic reticulum-golgi intermediate compartment protein 53 LMAN1 Lectin mannose-binding 1 protein ERGIC-53 intracellular mannose-specific lectin MR60

Statements

1 reference

13 November 2019

UniProt protein ID

Protein ERGIC-53

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49257

Concanavalin A-like lectin/glucanase domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49257

Legume-like lectin, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

unfolded protein binding

determination method or standard

1 reference

17 October 2017

Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

metal ion binding

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

protein binding

determination method or standard

7 references

17 October 2017

Molecular cloning of the oncofetal isoform of the human pancreatic bile salt-dependent lipase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

TMEM115 is an integral membrane protein of the Golgi complex involved in retrograde transport

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Crystal structure of the LMAN1-CRD/MCFD2 transport receptor complex provides insight into combined deficiency of factor V and factor VIII

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Structural basis for the cooperative interplay between the two causative gene products of combined factor V and factor VIII deficiency

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

carbohydrate binding

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

integral component of membrane

determination method or standard

determination method or standard

determination method or standard

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

host cell perinuclear region of cytoplasm

determination method or standard

1 reference

17 October 2017

Role of syntaxin 18 in the organization of endoplasmic reticulum subdomains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

endoplasmic reticulum

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

ER to Golgi transport vesicle membrane

determination method or standard

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

extracellular exosome

determination method or standard

1 reference

17 October 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

endoplasmic reticulum membrane

determination method or standard

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

ERGIC-53, a membrane protein of the endoplasmic reticulum-Golgi intermediate compartment, is identical to MR60, an intracellular mannose-specific lectin of myelomonocytic cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

endoplasmic reticulum-Golgi intermediate compartment

determination method or standard

3 references

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

determination method or standard

3 references

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

COPII-coated ER to Golgi transport vesicle

determination method or standard

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

biological process

Golgi organization

determination method or standard

1 reference

17 October 2017

The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

early endosome to Golgi transport

determination method or standard

1 reference

17 October 2017

The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

blood coagulation

determination method or standard

1 reference

17 October 2017

Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

positive regulation of organelle organization

determination method or standard

1 reference

17 October 2017

The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

protein N-linked glycosylation via asparagine

determination method or standard

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

COPII vesicle coating

determination method or standard

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

protein exit from endoplasmic reticulum

determination method or standard

1 reference

17 October 2017

The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

protein folding

determination method or standard

1 reference

17 October 2017

Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

protein transport

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

vesicle-mediated transport

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

endoplasmic reticulum to Golgi vesicle-mediated transport

determination method or standard

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

endoplasmic reticulum organization

determination method or standard

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

Legume-like lectin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49257

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000251047

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000251047

PDB structure ID

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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