Lectin, mannose binding 1 (Q21103045)

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mammalian protein found in Homo sapiens

ER-Golgi intermediate compartment 53 kDa protein
Gp58
endoplasmic reticulum-golgi intermediate compartment protein 53
LMAN1
Lectin mannose-binding 1
protein ERGIC-53
intracellular mannose-specific lectin MR60

Language	Label	Description	Also known as
English	Lectin, mannose binding 1	mammalian protein found in Homo sapiens	ER-Golgi intermediate compartment 53 kDa protein Gp58 endoplasmic reticulum-golgi intermediate compartment protein 53 LMAN1 Lectin mannose-binding 1 protein ERGIC-53 intracellular mannose-specific lectin MR60

Statements

1 reference

13 November 2019

UniProt protein ID

Protein ERGIC-53

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49257

Concanavalin A-like lectin/glucanase domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49257

Legume-like lectin, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

unfolded protein binding

determination method or standard

1 reference

17 October 2017

Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

metal ion binding

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

protein binding

determination method or standard

7 references

17 October 2017

Molecular cloning of the oncofetal isoform of the human pancreatic bile salt-dependent lipase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

TMEM115 is an integral membrane protein of the Golgi complex involved in retrograde transport

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Crystal structure of the LMAN1-CRD/MCFD2 transport receptor complex provides insight into combined deficiency of factor V and factor VIII

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Structural basis for the cooperative interplay between the two causative gene products of combined factor V and factor VIII deficiency

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

carbohydrate binding

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

integral component of membrane

determination method or standard

determination method or standard

determination method or standard

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

host cell perinuclear region of cytoplasm

determination method or standard

1 reference

17 October 2017

Role of syntaxin 18 in the organization of endoplasmic reticulum subdomains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

endoplasmic reticulum

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

ER to Golgi transport vesicle membrane

determination method or standard

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

extracellular exosome

determination method or standard

1 reference

17 October 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

endoplasmic reticulum membrane

determination method or standard

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

ERGIC-53, a membrane protein of the endoplasmic reticulum-Golgi intermediate compartment, is identical to MR60, an intracellular mannose-specific lectin of myelomonocytic cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

endoplasmic reticulum-Golgi intermediate compartment

determination method or standard

3 references

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

determination method or standard

3 references

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

COPII-coated ER to Golgi transport vesicle

determination method or standard

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

biological process

Golgi organization

determination method or standard

1 reference

17 October 2017

The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

early endosome to Golgi transport

determination method or standard

1 reference

17 October 2017

The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

blood coagulation

determination method or standard

1 reference

17 October 2017

Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

positive regulation of organelle organization

determination method or standard

1 reference

17 October 2017

The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

protein N-linked glycosylation via asparagine

determination method or standard

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

COPII vesicle coating

determination method or standard

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

protein exit from endoplasmic reticulum

determination method or standard

1 reference

17 October 2017

The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

protein folding

determination method or standard

1 reference

17 October 2017

Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

protein transport

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

vesicle-mediated transport

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

endoplasmic reticulum to Golgi vesicle-mediated transport

determination method or standard

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

endoplasmic reticulum organization

determination method or standard

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49257&geneProductId=UniProtKB:P49257

determination method or standard

Legume-like lectin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49257

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000251047

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000251047

PDB structure ID

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

Sitelinks

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Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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