TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans (Q27332459)

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English	TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans	scientific article

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scholarly article

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TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans (English)

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Caenorhabditis elegans

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Tar DNA-binding protein homolog 1 CELE_F44G4.4

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GOA release 2020-03-11

Arnaud Tauffenberger

object named as

Arnaud Tauffenberger

2

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Alexandra Vaccaro

object named as

Alexandra Vaccaro

1

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Leonard Petrucelli

5

object named as

Leonard Petrucelli

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author name string

Peter E A Ash

3

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Yari Carlomagno

4

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J Alex Parker

6

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language of work or name

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publication date

July 2012

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8

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7

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e1002806

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copyright license

Creative Commons Attribution 4.0 International

5 July 2012

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April 2022 Public Data File from Crossref

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3390363/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans

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Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans

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Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

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A C. elegans mutant that lives twice as long as wild type

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21 March 2017

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

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An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

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Opposing activities protect against age-onset proteotoxicity

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7 April 2017

daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans

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7 April 2017

Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

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7 April 2017

Caenorhabditis elegans RNA-processing protein TDP-1 regulates protein homeostasis and life span

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Stress signaling from the endoplasmic reticulum: A central player in the pathogenesis of amyotrophic lateral sclerosis.

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Understanding the role of TDP-43 and FUS/TLS in ALS and beyond.

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Neuron-specific proteotoxicity of mutant ataxin-3 in C. elegans: rescue by the DAF-16 and HSF-1 pathways

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A "two-hit" hypothesis for inclusion formation by carboxyl-terminal fragments of TDP-43 protein linked to RNA depletion and impaired microtubule-dependent transport

1 reference

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TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling

1 reference

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TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1.

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TDP-43 regulates its mRNA levels through a negative feedback loop

1 reference

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28 September 2017

Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy

1 reference

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Protein homeostasis and aging in neurodegeneration

1 reference

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28 September 2017

Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice

1 reference

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28 September 2017

Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules

1 reference

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28 September 2017

Neurotoxic effects of TDP-43 overexpression in C. elegans

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28 September 2017

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

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A Drosophila model for TDP-43 proteinopathy

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TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration

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Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis

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Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

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TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

1 reference

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TDP-43 is recruited to stress granules in conditions of oxidative insult.

1 reference

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Stress granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390363

28 September 2017

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

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Mechanisms of ageing: public or private?

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Protein synthesis and degradation during aging and senescence

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Intracellular protein synthesis, modifications and aging

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Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS.

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Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan

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Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2.

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10.1371/JOURNAL.PGEN.1002806

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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