Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence (Q27488844)

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scientific article (publication date: July 2009)

Language	Label	Description	Also known as
English	Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence	scientific article (publication date: July 2009)

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scholarly article

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1 reference

Europe PubMed Central

Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence (English)

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Hepatitis C virus

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based on heuristic

inferred from title

Barbara Rehermann

1

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language of work or name

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publication date

July 2009

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Journal of Clinical Investigation

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119

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7

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1745-54

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Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

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Human occludin is a hepatitis C virus entry factor required for infection of mouse cells

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Genomic Analysis Reveals a Potential Role for Cell Cycle Perturbation in HCV-Mediated Apoptosis of Cultured Hepatocytes

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Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27–restricted human immune response

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Tight Junction Proteins Claudin-1 and Occludin Control Hepatitis C Virus Entry and Are Downregulated during Infection To Prevent Superinfection

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High-programmed death-1 levels on hepatitis C virus-specific T cells during acute infection are associated with viral persistence and require preservation of cognate antigen during chronic infection

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Cell culture-produced hepatitis C virus does not infect peripheral blood mononuclear cells

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Hepatitis C virus immune escape via exploitation of a hole in the T cell repertoire

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Hepatitis C virus association with peripheral blood B lymphocytes potentiates viral infection of liver-derived hepatoma cells

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Stable Cytotoxic T Cell Escape Mutation in Hepatitis C Virus Is Linked to Maintenance of Viral Fitness

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Impaired Hepatitis C Virus (HCV)-Specific Effector CD8+ T Cells Undergo Massive Apoptosis in the Peripheral Blood during Acute HCV Infection and in the Liver during the Chronic Phase of Infection

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Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization

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Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

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High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome

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Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients

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Claudin-6 and claudin-9 function as additional coreceptors for hepatitis C virus

1 reference

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Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction

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Phenotypic and Functional Changes of Cytotoxic CD56pos Natural T Cells Determine Outcome of Acute Hepatitis C Virus Infection

1 reference

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20 March 2017

Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C

1 reference

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20 March 2017

Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

1 reference

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Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection

1 reference

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20 March 2017

PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

1 reference

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Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain

1 reference

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Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro

1 reference

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Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C

1 reference

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Robust hepatitis C virus infection in vitro

1 reference

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Divergent and convergent evolution after a common-source outbreak of hepatitis C virus

1 reference

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Cellular immune selection with hepatitis C virus persistence in humans

1 reference

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T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection.

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CD8 Epitope Escape and Reversion in Acute HCV Infection

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Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection

1 reference

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Binding of the Hepatitis C Virus Envelope Protein E2 to CD81 Inhibits Natural Killer Cell Functions

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Inhibition of Natural Killer Cells through Engagement of CD81 by the Major Hepatitis C Virus Envelope Protein

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Expression of hepatitis C virus proteins inhibits signal transduction through the Jak-STAT pathway

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Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein

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1 reference

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Natural killer cell function is intact after direct exposure to infectious hepatitis C virions.

1 reference

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29 September 2017

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1 reference

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29 September 2017

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1 reference

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Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection

1 reference

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Pathogenesis of hepatitis C-associated hepatocellular carcinoma

1 reference

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1 reference

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29 September 2017

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1 reference

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Hepatitis C virus core selectively suppresses interleukin-12 synthesis in human macrophages by interfering with AP-1 activation

1 reference

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Hepatitis C virus mutation affects proteasomal epitope processing

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29 September 2017

Neutralizing antibody response during acute and chronic hepatitis C virus infection

1 reference

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29 September 2017

Direct binding of hepatitis C virus core to gC1qR on CD4+ and CD8+ T cells leads to impaired activation of Lck and Akt.

1 reference

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29 September 2017

Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection

1 reference

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29 September 2017

Cross-genotype immunity to hepatitis C virus

1 reference

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Projecting future complications of chronic hepatitis C in the United States

1 reference

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Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

29 September 2017

Natural versus adaptive regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

29 September 2017

IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

29 September 2017

The lymphoid system in hepatitis C virus infection: autoimmunity, mixed cryoglobulinemia, and Overt B-cell malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

29 September 2017

Hepatitis C virus variants circumventing cytotoxic T lymphocyte activity as a mechanism of chronicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

29 September 2017

Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

29 September 2017

PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

2 June 2018

Functional suppression by FoxP3+CD4+CD25(high) regulatory T cells during acute hepatitis C virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Discordant role of CD4 T-cell response relative to neutralizing antibody and CD8 T-cell responses in acute hepatitis C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Intrahepatic virus-specific IL-10-producing CD8 T cells prevent liver damage during chronic hepatitis C virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Maintenance of HCV-specific T-cell responses in antibody-deficient patients a decade after early therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Mathematical modeling of primary hepatitis C infection: noncytolytic clearance and early blockage of virion production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Effects of antiviral therapy on the cellular immune response in acute hepatitis C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Mechanism of the interferon alpha response against hepatitis C virus replicons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: exploring the immunological mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Presence of functional dendritic cells in patients chronically infected with hepatitis C virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Chronic hepatitis C virus infection established and maintained in chimpanzees independent of dendritic cell impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Viral stress-inducible protein p56 inhibits translation by blocking the interaction of eIF3 with the ternary complex eIF2.GTP.Met-tRNAi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Extrahepatic manifestations of hepatitis C among United States male veterans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Protective immune response to hepatitis C virus in chimpanzees rechallenged following clearance of primary infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Hepatitis C infection in patients with primary hypogammaglobulinemia after treatment with contaminated immune globulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701885

27 November 2018

Relationship between interferon-gamma, interleukin-10, and interleukin-12 production in chronic hepatitis C and in vitro effects of interferon-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/19587449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-10 regulates plasmacytoid dendritic cell response to CpG-containing immunostimulatory sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/19587449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional B-cell response in intrahepatic lymphoid follicles in chronic hepatitis C

1 reference

https://pubmed.ncbi.nlm.nih.gov/19587449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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