Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization (Q27488289)

David A Price

10

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Gordon J. Freeman

11

Gordon J Freeman

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Emma Gostick

9

Emma Gostick

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E. John Wherry

12

E John Wherry

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author name string

Nobuhiro Nakamoto

1

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Jennifer Coleclough

3

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Yun Li

4

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Mary E Valiga

5

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Mary Kaminski

6

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Abraham Shaked

7

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Kim Olthoff

8

0 references

Kyong-Mi Chang

High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome

13

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language of work or name

English

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publication date

June 2008

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published in

Gastroenterology

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volume

134

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issue

7

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page(s)

1927-37, 1937.e1-2

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cites work

1 reference

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Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction

20 March 2017

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Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

20 March 2017

1 reference

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PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

20 March 2017

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Strain-Specific T-Cell Suppression and Protective Immunity in Patients with Chronic Hepatitis C Virus Infection

20 March 2017

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The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

20 March 2017

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Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection

20 March 2017

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Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production

20 March 2017

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Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

20 March 2017

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Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers

20 March 2017

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Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients

20 March 2017

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Analysis of successful immune responses in persons infected with hepatitis C virus

20 March 2017

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Restoring function in exhausted CD8 T cells during chronic viral infection

20 March 2017

1 reference

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20 March 2017

The B7 family revisited

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

20 March 2017

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Adaptive immune responses in acute and chronic hepatitis C virus infection

7 April 2017

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HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help

7 April 2017

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PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver.

7 April 2017

1 reference

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Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade

29 September 2017

1 reference

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Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

29 September 2017

1 reference

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PD-1 inhibits antiviral immunity at the effector phase in the liver

29 September 2017

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Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution.

29 September 2017

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The liver as a site of T-cell apoptosis: graveyard, or killing field?

29 September 2017

1 reference

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Pathogenesis, natural history, treatment, and prevention of hepatitis C.

29 September 2017

1 reference

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Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus

29 September 2017

1 reference

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Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection

29 September 2017

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Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction

2 June 2018

1 reference

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Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection

27 November 2018

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Discordant role of CD4 T-cell response relative to neutralizing antibody and CD8 T-cell responses in acute hepatitis C.

27 November 2018

1 reference

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Detailed analysis of intrahepatic CD8 T cells in the normal and hepatitis C-infected liver reveals differences in specific populations of memory cells with distinct homing phenotypes

27 November 2018

1 reference

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T-cell response relative to genotype and ethnicity during antiviral therapy for chronic hepatitis C.

27 November 2018

1 reference

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Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection

27 November 2018

1 reference

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The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities.

27 November 2018

1 reference

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Immunopathogenesis of hepatitis C virus infection

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18549878

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selective retention of activated CD8+ T cells by the normal liver

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18549878

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1053/J.GASTRO.2008.02.033

1 reference

1 reference

1 reference

PubMed publication ID

18549878

1 reference