A miniaturized technique for assessing protein thermodynamics and function using fast determination of quantitative cysteine reactivity (Q30400559)

8 November 2017

A miniaturized technique for assessing protein thermodynamics and function using fast determination of quantitative cysteine reactivity (English)

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8 November 2017

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4

Homme W Hellinga

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Terrence G Oas

series ordinal

3

object named as

Terrence G Oas

1 reference

8 November 2017

Daniel G Isom

1

1 reference

8 November 2017

Philippe R Marguet

series ordinal

2

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8 November 2017

language of work or name

English

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publication date

5 January 2011

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8 November 2017

14

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inferred from page(s)

published in

Proteins

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8 November 2017

79

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8 November 2017

4

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8 November 2017

1034-1047

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Fluorescent and colorimetric probes for detection of thiols

8 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Picomole-scale characterization of protein stability and function by quantitative cysteine reactivity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Systems biology from a yeast omics perspective

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Three-dimensional structural view of the central metabolic network of Thermotoga maritima

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Methods for the proteomic identification of protease substrates

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Lysine acetylation targets protein complexes and co-regulates major cellular functions

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Targeted rescue of a destabilized mutant of p53 by an in silico screened drug

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

A quantitative model of thermal stabilization and destabilization of proteins by ligands

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Metadegradomics: toward in vivo quantitative degradomics of proteolytic post-translational modifications of the cancer proteome.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Thermodynamic analysis of protein stability and ligand binding using a chemical modification- and mass spectrometry-based strategy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Structural genomics and drug discovery: all in the family

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Electrostatic effects in unfolded staphylococcal nuclease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Protein Structure Initiative: getting into gear.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Protein fabrication automation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Attributes of glycosylation in the establishment of the unfolding pathway of soybean agglutinin.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Quantification of protein half-lives in the budding yeast proteome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Lessons in stability from thermophilic proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Global analysis of protein phosphorylation in yeast

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Protein production by auto-induction in high density shaking cultures

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Heat capacity in proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Pulse proteolysis: A simple method for quantitative determination of protein stability and ligand binding

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Analysis of allosteric signal transduction mechanisms in an engineered fluorescent maltose biosensor

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Global analysis of protein sumoylation in Saccharomyces cerevisiae

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Hydrogen exchange methods to study protein folding

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

High-throughput screening assay for the tunable selection of protein ligands

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

14 July 2018

Tissue sulfhydryl groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

A proteomics approach to understanding protein ubiquitination

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Regulation of tyrosine hydroxylase by stress-activated protein kinases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Construction of a fluorescent biosensor family

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Rapid mapping of protein structure, interactions, and ligand binding by misincorporation proton-alkyl exchange.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

High-density miniaturized thermal shift assays as a general strategy for drug discovery

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

What are the dielectric "constants" of proteins and how to validate electrostatic models?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Global analysis of protein activities using proteome chips

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Some thermodynamic implications for the thermostability of proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Measuring the conformational stability of a protein by hydrogen exchange

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Analysis of the pore structure of the influenza A virus M(2) ion channel by the substituted-cysteine accessibility method

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

A quantitative, high-throughput screen for protein stability

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Structure of the KcsA potassium channel from Streptomyces lividans: a site-directed spin labeling study of the second transmembrane segment

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Ionization-reactivity relationships for cysteine thiols in polypeptides.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Exploring the metabolic and genetic control of gene expression on a genomic scale

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Hydrogen exchange in chymotrypsin inhibitor 2 probed by denaturants and temperature

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Hydrogen exchange: the modern legacy of Linderstrøm-Lang

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Denaturant m values and heat capacity changes: relation to changes in accessible surface areas of protein unfolding

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Substrate stabilization of lysozyme to thermal and guanidine hydrochloride denaturation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Hydrogen Exchange in Proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Isolation and characterization of cysteine-containing regions of proteins using 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole and high-performance liquid chromatography.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

Calculation of protein extinction coefficients from amino acid sequence data

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139720

The V108M mutation decreases the structural stability of catechol O-methyltransferase.

14 July 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.22932

On the nature of conformational openings: native and unfolded-state hydrogen and thiol-disulfide exchange studies of ferric aquomyoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.22932

The equilibrium unfolding pathway of a (beta/alpha)8 barrel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.22932

Changes in side chain packing during apomyoglobin folding characterized by pulsed thiol-disulfide exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.22932

Unfolding rates of barstar determined in native and low denaturant conditions indicate the presence of intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.22932

Exploring the cooperativity of the fast folding reaction of a small protein using pulsed thiol labeling and mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.22932

Measurements of cysteine reactivity during protein unfolding suggest the presence of competing pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.22932

Hydrogen exchange of the tetramerization domain of the human tumour suppressor p53 probed by denaturants and temperature

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.22932

The structural stability of a protein is an important determinant of its proteolytic susceptibility in Escherichia coli

21 January 2018

1 reference

12 December 2020

Comparison of the conformational stability of the molten globule and native states of horse cytochrome c. Effects of acetylation, heat, urea and guanidine-hydrochloride

1 reference

12 December 2020

The heat capacity of proteins

1 reference

12 December 2020

Possible origin of differences between van't Hoff and calorimetric enthalpy estimates

1 reference

12 December 2020

Phosphorylation destabilizes the amino-terminal domain of enzyme I of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system

1 reference

12 December 2020

pKaValues and the pH Dependent Stability of the N-Terminal Domain of L9 as Probes of Electrostatic Interactions in the Denatured State. Differentiation between Local and Nonlocal Interactions†

1 reference

12 December 2020

Stabilization of Proteins by Ligand Binding: Application to Drug Screening and Determination of Unfolding Energetics

1 reference

12 December 2020

Identifiers

DOI

10.1002/PROT.22932

1 reference

8 November 2017

1 reference

8 November 2017

PubMed publication ID

21387407

1 reference