TPX2 impacts acetylation of histone H4 at lysine 16: implications for DNA damage response. (Q35387454): Difference between revisions

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English	TPX2 impacts acetylation of histone H4 at lysine 16: implications for DNA damage response.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 August 2017

TPX2 impacts acetylation of histone H4 at lysine 16: implications for DNA damage response. (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

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author name string

Gernot Neumayer

1

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Europe PubMed Central

PubMed publication ID

8 August 2017

Minh Dang Nguyen

2

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Europe PubMed Central

PubMed publication ID

8 August 2017

language of work or name

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publication date

3 November 2014

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Europe PubMed Central

PubMed publication ID

8 August 2017

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Europe PubMed Central

PubMed publication ID

8 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

e110994

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

TPX2: of spindle assembly, DNA damage response, and cancer

1 reference

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Overexpressed TPX2 causes ectopic formation of microtubular arrays in the nuclei of acentrosomal plant cells

1 reference

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Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

1 reference

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12 July 2018

Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repair

1 reference

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12 July 2018

Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation

1 reference

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TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes

1 reference

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SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60

1 reference

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Identification of a TPX2-like microtubule-associated protein in Drosophila

1 reference

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Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer

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BRCA1 tumour suppression occurs via heterochromatin-mediated silencing.

1 reference

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12 July 2018

Chfr and RNF8 synergistically regulate ATM activation

1 reference

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12 July 2018

Replication stress induces 53BP1-containing OPT domains in G1 cells

1 reference

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12 July 2018

Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events

1 reference

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12 July 2018

Hallmarks of Cancer: The Next Generation

1 reference

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12 July 2018

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

1 reference

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12 July 2018

DNA damage signaling in response to double-strand breaks during mitosis

1 reference

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Quantitative analysis of conditional gene inactivation using rationally designed, tetracycline-controlled miRNAs

1 reference

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12 July 2018

MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Solving the RIDDLE of 53BP1 recruitment to sites of damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Crosstalk between histone modifications during the DNA damage response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

CBP/p300-mediated acetylation of histone H3 on lysine 56

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Inhibition of SUV39H1 methyltransferase activity by DBC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A

1 reference

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12 July 2018

A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

The DNA damage response pathways: at the crossroad of protein modifications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

gammaH2AX foci form preferentially in euchromatin after ionising-radiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

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SIRT1 regulates the function of the Nijmegen breakage syndrome protein

1 reference

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A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination

1 reference

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The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly

1 reference

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A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites.

1 reference

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12 July 2018

MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

1 reference

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12 July 2018

The histone code at DNA breaks: a guide to repair?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Involvement of human MOF in ATM function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

The mechanism of spindle assembly: functions of Ran and its target TPX2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

DNA damage-induced activation of ATM and ATM-dependent signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Interaction of histone acetylases and deacetylases in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Human TPX2 is required for targeting Aurora-A kinase to the spindle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

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Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death

1 reference

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12 July 2018

Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

TPX2, A novel xenopus MAP involved in spindle pole organization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Megabase chromatin domains involved in DNA double-strand breaks in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

12 July 2018

Cell cycle. Some importin news about spindle assembly

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0110994

21 January 2018

Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells

1 reference

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26 September 2018

Determinants for Aurora-A activation and Aurora-B discrimination by TPX2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217740

26 September 2018

Identifiers

10.1371/JOURNAL.PONE.0110994

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

ResearchGate publication ID

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