Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach (Q37699332)

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scientific article published on March 2010

Language	Label	Description	Also known as
English	Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach	scientific article published on March 2010

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PMC publication ID

2893734

retrieved

22 August 2017

review article

1 reference

stated in

Europe PubMed Central

title

Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach (English)

1 reference

stated in

Europe PubMed Central

PMC publication ID

2893734

retrieved

22 August 2017

main subject

chemotherapy

1 reference

based on heuristic

inferred from title

natural product

1 reference

based on heuristic

inferred from title

natural product chemistry

1 reference

based on heuristic

inferred from title

author name string

Kuo-Hsiung Lee

series ordinal

1

1 reference

stated in

Europe PubMed Central

PMC publication ID

2893734

retrieved

22 August 2017

language of work or name

English

1 reference

based on heuristic

inferred from title

publication date

1 March 2010

1 reference

stated in

Europe PubMed Central

PMC publication ID

2893734

retrieved

22 August 2017

published in

Journal of Natural Products

1 reference

stated in

Europe PubMed Central

PMC publication ID

2893734

retrieved

22 August 2017

volume

73

1 reference

stated in

Europe PubMed Central

PMC publication ID

2893734

retrieved

22 August 2017

issue

3

1 reference

stated in

Europe PubMed Central

PMC publication ID

2893734

retrieved

22 August 2017

page(s)

500-516

1 reference

stated in

Europe PubMed Central

PMC publication ID

2893734

retrieved

22 August 2017

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Antitumor agents. 258. Syntheses and evaluation of dietary antioxidant--taxoid conjugates as novel cytotoxic agents

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Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents

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New developments in the chemistry and biology of the bioactive constituents of Tanshen

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Current developments in the discovery and design of new drug candidates from plant natural product leads

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PA-457: A potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing

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Research and future trends in the pharmaceutical development of medicinal herbs from Chinese medicine.

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New constituents and antiplatelet aggregation and anti-HIV principles of Artemisia capillaris

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Anti-AIDS agents part 41: synthesis and anti-HIV activity of 3',4'-di-o-(-)-camphanoyl-(+)-cis-khellactone (DCK) lactam analogues

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Sesquiterpene alkaloids from Tripterygium hypoglaucum and Tripterygium wilfordii: a new class of potent anti-HIV agents

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Anti-AIDS agents, 1. Isolation and characterization of four new tetragalloylquinic acids as a new class of HIV reverse transcriptase inhibitors from tannic acid

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Antitumor agents 260. New desmosdumotin B analogues with improved in vitro anticancer activity

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CHM-1 inhibits hepatocyte growth factor-induced invasion of SK-Hep-1 human hepatocellular carcinoma cells by suppressing matrix metalloproteinase-9 expression.

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Antitumor agents 253. Design, synthesis, and antitumor evaluation of novel 9-substituted phenanthrene-based tylophorine derivatives as potential anticancer agents.

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Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis

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Antitumor agents. 254. Synthesis and biological evaluation of novel neo-tanshinlactone analogues as potent anti-breast cancer agents

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14 September 2017

Antitumor agents 251: synthesis, cytotoxic evaluation, and structure-activity relationship studies of phenanthrene-based tylophorine derivatives (PBTs) as a new class of antitumor agents

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Antitumor agents 247. New 4-ethoxycarbonylethyl curcumin analogs as potential antiandrogenic agents

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Mechanism of action and resistant profile of anti-HIV-1 coumarin derivatives.

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Antitumor Agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza

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Antitumor agents. 234. Design, synthesis, and biological evaluation of novel 4beta-[(4' '-benzamido)-amino]-4'-o-demethyl-epipodophyllotoxin derivatives

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Anti-AIDS agents. 60. Substituted 3'R,4'R-di-O-(-)-camphanoyl-2',2'-dimethyldihydropyrano[2,3-f]chromone (DCP) analogues as potent anti-HIV agents

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Antitumor agents. Part 235: Novel 4'-ester etoposide analogues as potent DNA topoisomerase II inhibitors with improved therapeutic potential

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14 September 2017

Anti-AIDS agents. Part 58: synthesis and anti-HIV activity of 1-thia-di-O-(-)-camphanoyl-(+)-cis-khellactone (1-thia-DCK) analogues

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14 September 2017

Anti-AIDS agents. Part 57: Actein, an anti-HIV principle from the rhizome of Cimicifuga racemosa (black cohosh), and the anti-HIV activity of related saponins

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14 September 2017

Anti-AIDS agents. 52. Synthesis and anti-HIV activity of hydroxymethyl (3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone derivatives

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14 September 2017

Anti-AIDS agents 54. A potent anti-HIV chalcone and flavonoids from genus Desmos

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14 September 2017

Antitumor agents 216. Synthesis and evaluation of paclitaxel-camptothecin conjugates as novel cytotoxic agents

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14 September 2017

Sesquiterpene Antitumor Agents: Inhibitors of Cellular Metabolism

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Antitumor Agents. 211. Fluorinated 2-phenyl-4-quinolone derivatives as antimitotic antitumor agents

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28 September 2017

Anti-AIDS agents. 31. Synthesis and anti-HIV activity of 4-substituted 3',4'-di-O-(-)-camphanoyl-(+)-cis-khellactone (DCK) thiolactone analogs

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28 September 2017

Anti-AIDS agents--XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues

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28 September 2017

Synthesis of cytotoxic fluorinated quassinoids

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28 September 2017

Antitumor agents. 163. Three-dimensional quantitative structure-activity relationship study of 4'-O-demethylepipodophyllotoxin analogs using the modified CoMFA/q2-GRS approach

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28 September 2017

Anti-AIDS agents, 18. Sodium and potassium salts of caffeic acid tetramers from Arnebia euchroma as anti-HIV agents

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28 September 2017

Suksdorfin: an anti-HIV principle from Lomatium suksdorfii, its structure-activity correlation with related coumarins, and synergistic effects with anti-AIDS nucleosides

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28 September 2017

Anti-AIDS (acquired immune deficiency syndrome) agents. 17. New brominated hexahydroxybiphenyl derivatives as potent anti-HIV agents

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28 September 2017

Anti-AIDS agents. 15. Synthesis and anti-HIV activity of dihydroseselins and related analogs

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28 September 2017

Identification of ent-16 beta, 17-dihydroxykauran-19-oic acid as an anti-HIV principle and isolation of the new diterpenoids annosquamosins A and B from Annona squamosa.

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23 June 2018

Betulinic acid derivatives: a new class of specific inhibitors of human immunodeficiency virus type 1 entry

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23 June 2018

Betulinic acid and dihydrobetulinic acid derivatives as potent anti-HIV agents

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23 June 2018

Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids

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23 June 2018

Cytotoxicity of sesquiterpene lactones.

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23 June 2018

Antimalarial agents. 1. alpha-Santonin-derived cyclic peroxide as potential antimalarial agent

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23 June 2018

Effect of 4 beta-arylamino derivatives of 4'-O-demethylepipodophyllotoxin on human DNA topoisomerase II, tubulin polymerization, KB cells, and their resistant variants

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23 June 2018

Antitumor agents, 127. Bruceoside C, a new cytotoxic quassinoid glucoside, and related compounds from Brucea javanica

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23 June 2018

Tumor inhibitors. 100. Isolation and structural elucidation of bruceantin and bruceantinol, new potent antileukemic quassinoids from Brucea antidysenterica

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23 June 2018

Cell differentiation enhancement by hydrophilic derivatives of 4,8-dihydrobenzo[1,2-b:5,4-b']dithiophene-4,8-diones in HL-60 leukemia cells

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1 September 2018

Synthesis and anti-HIV activity of bi-functional betulinic acid derivatives

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1 September 2018

Anti-AIDS agents 49. Synthesis, anti-HIV, and anti-fusion activities of IC9564 analogues based on betulinic acid

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1 September 2018

Anti-AIDS agents. 48.(1) Anti-HIV activity of moronic acid derivatives and the new melliferone-related triterpenoid isolated from Brazilian propolis.

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PubMed Central

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1 September 2018

Antitumor agents 210. Synthesis and evaluation of taxoid-epipodophyllotoxin conjugates as novel cytotoxic agents

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PubMed Central

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1 September 2018

Chemical constituents of Prangos tschiniganica; structure elucidation and absolute configuration of coumarin and furanocoumarin derivatives with anti-HIV activity.

1 reference

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PubMed Central

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1 September 2018

Bruceosides D, E, and F, three new cytotoxic quassinoid glucosides from Brucea javanica

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20187635

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12 December 2020

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Antitumor agents. 3. Synthesis and cytotoxic activity of helenalin amine adducts and related derivatives

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PubMed

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12 December 2020

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Synthesis and cytotoxicity of methyl-4,8-dihydrobenzo[1,2-b:5,4-b']dithiophene-4,8-dione derivatives

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20187635

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12 December 2020

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Antitumor agents, 107. New cytotoxic 4-alkylamino analogues of 4'-demethyl-epipodophyllotoxin as inhibitors of human DNA topoisomerase II

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20187635

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12 December 2020

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Antimalaria studies on Qinghaosu

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20187635

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12 December 2020

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Antitumor agents. 113. New 4 beta-arylamino derivatives of 4'-O-demethylepipodophyllotoxin and related compounds as potent inhibitors of human DNA topoisomerase II

1 reference

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PubMed

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retrieved

12 December 2020

based on heuristic

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Antitumor agents XLV: Bisbrusatolyl and brusatolyl esters and related compounds as novel potent antileukemic agents

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20187635

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12 December 2020

based on heuristic

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Antitumor Agents. 49. Tricin,Kaempferol-3-0-β-D-Glucopyranoside and (+)-Nortrachelogenin, Antileukemic Principles From Wikstroemia indica

1 reference

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12 December 2020

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Antitumor agents. 172. Synthesis and biological evaluation of novel deacetamidothiocolchicin-7-ols and ester analogs as antitubulin agents

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12 December 2020

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Synthesis and antimitotic activity of glycosidic lignan derivatives related to podophyllotoxin

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20187635

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12 December 2020

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Antitumor agents. 120. New 4-substituted benzylamine and benzyl ether derivatives of 4'-O-demethylepipodophyllotoxin as potent inhibitors of human DNA topoisomerase II

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20187635

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor agents. 178. Synthesis and biological evaluation of substituted 2-aryl-1,8-naphthyridin-4(1H)-ones as antitumor agents that inhibit tubulin polymerization

1 reference

stated in

PubMed

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https://pubmed.ncbi.nlm.nih.gov/20187635

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12 December 2020

based on heuristic

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Antitumor agents. 44. Bis(helenalinyl) esters and related derivatives as novel potent antileukemic agents

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20187635

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Identifiers

DOI

10.1021/NP900821E

1 reference

stated in

Europe PubMed Central

PMC publication ID

2893734

retrieved

22 August 2017

PMC publication ID

2893734

1 reference

stated in

Europe PubMed Central

PMC publication ID

2893734

retrieved

22 August 2017

PubMed publication ID

20187635

1 reference

stated in

Europe PubMed Central

PMC publication ID

2893734

retrieved

22 August 2017

ResearchGate publication ID

41620238

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