Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome (Q38985852)

8 September 2017

title

Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome (English)

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8 September 2017

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Hao Xu

1

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8 September 2017

Jieling Yang

2

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8 September 2017

Wenqing Gao

3

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8 September 2017

Lin Li

4

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8 September 2017

Peng Li

5

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8 September 2017

Li Zhang

6

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8 September 2017

Yi-Nan Gong

7

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8 September 2017

Xiaolan Peng

8

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8 September 2017

Jianzhong Jeff Xi

9

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8 September 2017

She Chen

10

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8 September 2017

Fengchao Wang

11

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8 September 2017

Feng Shao

12

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8 September 2017

language of work or name

English

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publication date

11 June 2014

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8 September 2017

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8 September 2017

volume

513

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8 September 2017

issue

7517

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8 September 2017

page(s)

237-241

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Pyrin levels in human monocytes and monocyte-derived macrophages regulate IL-1beta processing and release

8 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE13449

A candidate gene for familial Mediterranean fever

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE13449

Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Structure and mode of action of clostridial glucosylating toxins: the ABCD model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

The role of toxin A and toxin B in Clostridium difficile infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Toxin B is essential for virulence of Clostridium difficile

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Non-canonical inflammasome activation targets caspase-11

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

The Actin cross-linking domain of the Vibrio cholerae RTX toxin directly catalyzes the covalent cross-linking of actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Inactivation of small Rho GTPases by the multifunctional RTX toxin from Vibrio cholerae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Bacterial protein toxins that modify host regulatory GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Comparative analysis of Histophilus somni immunoglobulin-binding protein A (IbpA) with other fic domain-containing enzymes reveals differences in substrate and nucleotide specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

The fic domain: regulation of cell signaling by adenylylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE13449

Ras, Rap, and Rac small GTP-binding proteins are targets for Clostridium sordellii lethal toxin glucosylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Inhibition of Fc epsilon-RI-mediated activation of rat basophilic leukemia cells by Clostridium difficile toxin B (monoglucosyltransferase)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Botulinum ADP-ribosyltransferase C3: a new tool to study low molecular weight GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Clostridium difficile glucosyltransferase toxin B-essential amino acids for substrate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Salmonella Typhimurium type III secretion effectors stimulate innate immune responses in cultured epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

The Type VI secretion system of Burkholderia cenocepacia affects multiple Rho family GTPases disrupting the actin cytoskeleton and the assembly of NADPH oxidase complex in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Activation of the pyrin inflammasome by intracellular Burkholderia cenocepacia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Pyrin and ASC co-localize to cellular sites that are rich in polymerizing actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

21 January 2018

The plant immune system

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Chemical probing reveals insights into the signaling mechanism of inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Determination of GTP loading on Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Vibrio parahaemolyticus effector proteins suppress inflammasome activation by interfering with host autophagy signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13449

Inactivation of Ras by Clostridium sordellii lethal toxin-catalyzed glucosylation

21 January 2018

1 reference

12 December 2020

Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases

1 reference

12 December 2020

A system for the construction of targeted unmarked gene deletions in the genus Burkholderia

1 reference

12 December 2020

Burkholderia cenocepacia disrupts host cell actin cytoskeleton by inactivating Rac and Cdc42

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE13449

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Dimensions Publication ID

8 September 2017

1005258404

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