Pages that link to "Q35103069"

The following pages link to Cyclin-dependent kinase inhibitors attenuate protein hyperphosphorylation, cytoskeletal lesion formation, and motor defects in Niemann-Pick Type C mice (Q35103069):

Displaying 41 items.

• Tau deletion exacerbates the phenotype of Niemann-Pick type C mice and implicates autophagy in pathogenesis. (Q24328779) (← links)
• Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease (Q24657243) (← links)
• Neuronal response in Alzheimer's and Parkinson's disease: the effect of toxic proteins on intracellular pathways (Q26779424) (← links)
• Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models (Q28475093) (← links)
• Photoreactivity of indirubin derivatives. (Q33326991) (← links)
• Corneal alterations during combined therapy with cyclodextrin/allopregnanolone and miglustat in a knock-out mouse model of NPC1 disease (Q34097846) (← links)
• Long- and short-term CDK5 knockdown prevents spatial memory dysfunction and tau pathology of triple transgenic Alzheimer's mice (Q34159111) (← links)
• Tau, prions and Aβ: the triad of neurodegeneration (Q34463061) (← links)
• Alterations in gene expression in mutant amyloid precursor protein transgenic mice lacking Niemann-Pick type C1 protein (Q34575511) (← links)
• Cell cycle molecules define a pathway required for neuron death in development and disease (Q34602967) (← links)
• Niemann-Pick type C pathogenesis and treatment: from statins to sugars. (Q34632493) (← links)
• Mitotic spindle defects and chromosome mis-segregation induced by LDL/cholesterol-implications for Niemann-Pick C1, Alzheimer's disease, and atherosclerosis. (Q34673948) (← links)
• Increased CDK5 expression in HIV encephalitis contributes to neurodegeneration via tau phosphorylation and is reversed with Roscovitine (Q34805533) (← links)
• Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies (Q35839667) (← links)
• 5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of Alzheimer disease (Q36299503) (← links)
• Involvement of calpain activation in neurodegenerative processes. (Q36588397) (← links)
• Analysis of transcriptional profiles and functional clustering of global cerebellar gene expression in PCD3J mice (Q37065977) (← links)
• Astrocyte-only Npc1 reduces neuronal cholesterol and triples life span of Npc1-/- mice (Q37080277) (← links)
• Pyrazolo[1,5-a]-1,3,5-triazine as a purine bioisostere: access to potent cyclin-dependent kinase inhibitor (R)-roscovitine analogue. (Q37098618) (← links)
• Genome sequencing in a case of Niemann-Pick type C (Q37416674) (← links)
• Targeting tau protein in Alzheimer's disease (Q37744878) (← links)
• Silencing of CDK5 as potential therapy for Alzheimer's disease (Q37863144) (← links)
• Role of cell cycle re-entry in neurons: a common apoptotic mechanism of neuronal cell death (Q37941527) (← links)
• Sustained (S)-roscovitine delivery promotes neuroprotection associated with functional recovery and decrease in brain edema in a randomized blind focal cerebral ischemia study. (Q38751348) (← links)
• Cell cycle inhibition attenuates microglial proliferation and production of IL-1beta, MIP-1alpha, and NO after focal cerebral ischemia in the rat. (Q39900532) (← links)
• Packaging and functional identification of recombinant adeno-associated virus encoding cdc2-siRNA. (Q39901925) (← links)
• The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling (Q40202913) (← links)
• Induction of polyploidization in leukemic cell lines and primary bone marrow by Src kinase inhibitor SU6656. (Q40464481) (← links)
• Molecular modeling studies of 4,5-dihydro-1H-pyrazolo[4,3-h] quinazoline derivatives as potent CDK2/Cyclin a inhibitors using 3D-QSAR and docking (Q41239527) (← links)
• Indirubin-3'-monoxime suppresses amyloid-beta-induced apoptosis by inhibiting tau hyperphosphorylation (Q41943398) (← links)
• Mitotic epitopes are incorporated into age-dependent neurofibrillary tangles in Niemann-Pick disease type C. (Q45992751) (← links)
• Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. (Q46303283) (← links)
• Brain 5-lipoxygenase over-expression worsens memory, synaptic integrity, and tau pathology in the P301S mice (Q47438369) (← links)
• Aberrant activation of Cdc2/cyclin B1 is involved in initiation of cytoskeletal pathology in murine Niemann-Pick disease type C. (Q47617752) (← links)
• p35/Cyclin-dependent kinase 5 is required for protection against beta-amyloid-induced cell death but not tau phosphorylation by ceramide (Q48212381) (← links)
• p35/p25 is not essential for tau and cytoskeletal pathology or neuronal loss in Niemann-Pick type C disease. (Q48624305) (← links)
• Iminosugar-based inhibitors of glucosylceramide synthase prolong survival but paradoxically increase brain glucosylceramide levels in Niemann-Pick C mice. (Q48641010) (← links)
• Cyclin-dependent kinase inhibition with roscovitine: neuroprotection in acute ischemic stroke. (Q48728908) (← links)
• Mitogen-activated protein kinase activity may not be necessary for the neuropathology of Niemann-Pick type C mice (Q48933912) (← links)
• [Molecular principles of tau-induced toxicity: new experimental therapy strategies for treatment of Alzheimer's disease]. (Q53312752) (← links)
• The neuroprotective effects of cyclin-dependent kinase-5 inhibition in mice with Niemann-Pick disease type C. (Q54740058) (← links)