The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling (Q40202913)

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scientific article published on 29 November 2006

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English	The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling	scientific article published on 29 November 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling (English)

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Europe PubMed Central

PubMed publication ID

18 September 2017

3

object named as

Kay E Davies

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Europe PubMed Central

PubMed publication ID

18 September 2017

author name string

Emmanuelle Bitoun

1

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Europe PubMed Central

PubMed publication ID

18 September 2017

Peter L Oliver

2

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Europe PubMed Central

PubMed publication ID

18 September 2017

publication date

29 November 2006

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Europe PubMed Central

PubMed publication ID

18 September 2017

Human Molecular Genetics

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Europe PubMed Central

PubMed publication ID

18 September 2017

16

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

92-106

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Quantitative acute leukemia cytogenetics

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

MLL: a histone methyltransferase disrupted in leukemia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

LAF4, an AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23)

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

A candidate gene for mild mental handicap at the FRAXE fragile site

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Exon/intron structure of the human AF-4 gene, a member of the AF-4/LAF-4/FMR-2 gene family coding for a nuclear protein with structural alterations in acute leukaemia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Cloning and developmental expression of the murine homolog of the acute leukemia proto-oncogene AF4

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Fragile XE-associated familial mental retardation protein 2 (FMR2) acts as a potent transcription activator

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Interaction of AF4 wild-type and AF4.MLL fusion protein with SIAH proteins: indication for t(4;11) pathobiology?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Mediation of Af4 protein function in the cerebellum by Siah proteins

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Ubiquitin-mediated proteolysis: biological regulation via destruction

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

The robotic mouse: unravelling the function of AF4 in the cerebellum

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Transcriptional coactivator complexes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

An RNA polymerase II elongation factor encoded by the human ELL gene

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Control of elongation by RNA polymerase II

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Identification of multiple cyclin subunits of human P-TEFb

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Transcriptional elongation by RNA polymerase II and histone methylation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

The diverse functions of histone lysine methylation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Tails of intrigue: phosphorylation of RNA polymerase II mediates histone methylation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

hDOT1L links histone methylation to leukemogenesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

t(10;11)-acute leukemias with MLL-AF10 and MLL-ABI1 chimeric transcripts: specific expression patterns of ABI1 gene in leukemia and solid tumor cell lines

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

MLL fusion partners AF4 and AF9 interact at subnuclear foci

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Feeding the machine: mechanisms of proteasome-catalyzed degradation of ubiquitinated proteins

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

cDNA cloning, expression and chromosomal localization of the murine AF-4 gene involved in human leukemia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

The CDC2-related kinase PITALRE is the catalytic subunit of active multimeric protein complexes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3' end processing

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

NF-kappaB binds P-TEFb to stimulate transcriptional elongation by RNA polymerase II.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Activation of MyoD-dependent transcription by cdk9/cyclin T2

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Decreased cyclin dependent kinase in brain of patients with Down syndrome

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

ORP150/HSP12A regulates Purkinje cell survival: a role for endoplasmic reticulum stress in cerebellar development

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Regulation of contextual fear conditioning by baseline and inducible septo-hippocampal cyclin-dependent kinase 5.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Constitutive expression of heat shock protein HSP25 in the central nervous system of the developing and adult mouse

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Expression of CDK5 (PSSALRE kinase), a neural cdc2-related protein kinase, in the mature and developing mouse central and peripheral nervous systems

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Epigenetic mechanisms in memory formation.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Dot1a-AF9 complex mediates histone H3 Lys-79 hypermethylation and repression of ENaCalpha in an aldosterone-sensitive manner

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Cycling at the interface between neurodevelopment and neurodegeneration

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Cyclin-dependent kinase inhibitors attenuate protein hyperphosphorylation, cytoskeletal lesion formation, and motor defects in Niemann-Pick Type C mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Methylation and acetylation in nervous system development and neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Transcription elongation and human disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Loss-of-function mutation of the AF9/MLLT3 gene in a girl with neuromotor development delay, cerebellar ataxia, and epilepsy.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Expression of the murine homologue of FMR2 in mouse brain and during development

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Localization of the fragile X mental retardation 2 (FMR2) protein in mammalian brain.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Cerebellar contributions to cognition

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Cerebellar function in consolidation of a motor memory

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Cerebellum-dependent learning: the role of multiple plasticity mechanisms

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Molecular pathogenesis of MLL-associated leukemias

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Common mechanism for oncogenic activation of MLL by forkhead family proteins

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Mechanisms of transformation by MLL.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

The MLL recombinome of acute leukemias

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Leukemogenic MLL fusion proteins bind across a broad region of the Hox a9 locus, promoting transcription and multiple histone modifications

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL444

21 January 2018

Identifiers

10.1093/HMG/DDL444

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

ResearchGate publication ID

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