Deleted in colorectal carcinoma (Q14905677)

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mammalian protein found in Mus musculus

• Dcc
• tumor suppressor protein DCC
• netrin receptor DCC

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Language	Label	Description	Also known as
English	Deleted in colorectal carcinoma	mammalian protein found in Mus musculus	Dcc tumor suppressor protein DCC netrin receptor DCC

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P70211

part of

Fibronectin type III superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P70211

Immunoglobulin-like fold

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P70211

netrin receptor DCC

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P70211

Immunoglobulin-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P70211

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Immunoglobulin I-set, protein family

1 reference

based on heuristic

inferred from protein domain or family

Fibronectin type III, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

Neogenin, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin subtype 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

house mouse

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P70211

encoded by

Dcc

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P70211

molecular function

protein binding

determination method

IPI

3 references

retrieved

14 February 2019

stated in

Interaction of Myc-associated zinc finger protein with DCC, the product of a tumor-suppressor gene, during the neural differentiation of P19 EC cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IPI

retrieved

14 February 2019

stated in

Interaction of Myc-associated zinc finger protein with DCC, the product of a tumor-suppressor gene, during the neural differentiation of P19 EC cells

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IPI

retrieved

14 February 2019

stated in

DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IPI

transcription coactivator activity

determination method

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

ISO

netrin receptor activity

determination method

IEA

ISO

2 references

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

ISO

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IEA

identical protein binding

determination method

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

ISO

cell component

integral component of membrane

determination method

IEA

2 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P70211

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IEA

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IEA

membrane

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P70211

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IEA

plasma membrane

determination method

TAS

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

TAS

axon

determination method

IDA

ISO

2 references

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

ISO

retrieved

14 February 2019

stated in

Netrin-1 and DCC mediate axon guidance locally at the optic disc: loss of function leads to optic nerve hypoplasia

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IDA

growth cone membrane

determination method

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

ISO

membrane raft

determination method

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

ISO

Schaffer collateral - CA1 synapse

determination method

IDA

IMP

2 references

retrieved

14 February 2019

stated in

DCC expression by neurons regulates synaptic plasticity in the adult brain

GOA

curator

SynGO

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IMP

retrieved

14 February 2019

stated in

DCC expression by neurons regulates synaptic plasticity in the adult brain

GOA

curator

SynGO

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IDA

integral component of postsynaptic density membrane

determination method

IDA

1 reference

retrieved

14 February 2019

stated in

DCC expression by neurons regulates synaptic plasticity in the adult brain

GOA

curator

SynGO

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IDA

biological process

dorsal/ventral axon guidance

determination method

IMP

1 reference

retrieved

14 February 2019

stated in

Diffusion tensor magnetic resonance imaging and tract-tracing analysis of Probst bundle structure in Netrin1- and DCC-deficient mice

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IMP

neuron migration

determination method

IMP

1 reference

retrieved

14 February 2019

stated in

Molecular control of spinal accessory motor neuron/axon development in the mouse spinal cord

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IMP

nervous system development

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IEA

multicellular organism development

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P70211

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IEA

regulation of neuron death

determination method

IEA

ISO

2 references

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

ISO

retrieved

14 February 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IEA

spinal cord ventral commissure morphogenesis

determination method

IMP

1 reference

retrieved

14 February 2019

stated in

Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IMP

anterior/posterior axon guidance

determination method

IMP

1 reference

retrieved

14 February 2019

stated in

Topography of thalamic projections requires attractive and repulsive functions of Netrin-1 in the ventral telencephalon

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IMP

apoptotic process

determination method

IEA

2 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P70211

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IEA

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IEA

netrin-activated signaling pathway

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IEA

axon guidance

determination method

IEA

ISO

2 references

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

ISO

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IEA

positive regulation of neuron projection development

determination method

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

ISO

positive regulation of ERK1 and ERK2 cascade

determination method

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

ISO

positive regulation of nucleic acid-templated transcription

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IEA

postsynaptic modulation of chemical synaptic transmission

determination method

IMP

1 reference

retrieved

14 February 2019

stated in

DCC expression by neurons regulates synaptic plasticity in the adult brain

GOA

curator

SynGO

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70211

determination method

IMP

has part(s)

immunoglobulin subtype

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P70211

fibronectin type III

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P70211

immunoglobulin subtype 2

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P70211

Neogenin, C-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P70211

immunoglobulin-like domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P70211

immunoglobulin I-set

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P70211

Identifiers

RefSeq protein ID

NP_031857

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

13176

XP_006525651

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

13176

UniProt protein ID

P70211

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P70211

Ensembl protein ID

ENSMUSP00000073094

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000073094

ENSMUSP00000110593

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000110593

PDB structure ID

3PZD

1 reference

stated in

UniProt

UniProt protein ID

P70211

retrieved

9 August 2016

language of work or name

English

4PLO

1 reference

stated in

UniProt

UniProt protein ID

P70211

retrieved

9 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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