The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter (Q24294427)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17251190%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17251190%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

SMAD family member 3

1 reference

RNA polymerase II-specific DNA-binding transcription factor binding

1 reference

Paired box 6

1 reference

author

Timothy Grocott

1

1 reference

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24 December 2019

Terje Johansen

4

1 reference

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24 December 2019

Michael Wormstone

7

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24 December 2019

author name string

Victoria Frost

2

1 reference

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24 December 2019

Marjorie Maillard

3

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24 December 2019

Grant N Wheeler

5

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24 December 2019

Lucy J Dawes

6

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24 December 2019

Andrew Chantry

8

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24 December 2019

language of work or name

English

0 references

publication date

23 January 2007

1 reference

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24 December 2019

published in

Nucleic Acids Research

1 reference

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24 December 2019

volume

35

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24 December 2019

issue

3

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24 December 2019

page(s)

890-901

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17251190%20AND%20SRC:MED&resulttype=core&format=json

The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions

24 December 2019

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19 March 2017

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Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins

19 March 2017

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Smad1 interacts with homeobox DNA-binding proteins in bone morphogenetic protein signaling

19 March 2017

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19 March 2017

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Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye

6 April 2017

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19 March 2017

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TGF-beta-activated Smad3 represses MEF2-dependent transcription in myogenic differentiation

27 September 2017

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Functional properties of natural human PAX6 and PAX6(5a) mutants

27 September 2017

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Conservation of Pax 6 function and upstream activation by Notch signaling in eye development of frogs and flies

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Dual roles for Pax-6: a transcriptional repressor of lens fiber cell-specific beta-crystallin genes.

27 September 2017

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27 September 2017

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Disruption of PAX6 function in mice homozygous for the Pax6Sey-1Neu mutation produces abnormalities in the early development and regionalization of the diencephalon

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

30 May 2018

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Transcriptional regulation of the human PAX6 gene promoter

30 May 2018

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30 May 2018

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Ectopic Pax6 expression disturbs lens fiber cell differentiation.

30 May 2018

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Aberrant lens fiber differentiation in anterior subcapsular cataract formation: a process dependent on reduced levels of Pax6.

29 November 2018

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Conserved elements in Pax6 intron 7 involved in (auto)regulation and alternative transcription

29 November 2018

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The functional interaction between the paired domain transcription factor Pax8 and Smad3 is involved in transforming growth factor-beta repression of the sodium/iodide symporter gene

29 November 2018

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BMP signaling patterns the dorsal and intermediate neural tube via regulation of homeobox and helix-loop-helix transcription factors.

29 November 2018

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Fgf receptor signaling plays a role in lens induction.

29 November 2018

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Transforming growth factor-beta 1 regulates the expression of Pax-2, a developmental control gene, in renal tubule cells.

29 November 2018

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Quail Pax-6 (Pax-QNR) encodes a transcription factor able to bind and trans-activate its own promoter.

29 November 2018

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Directing pluripotent cell differentiation using "diced RNA" in transient transfection

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17251190

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Truncated forms of Pax-6 disrupt lens morphology in transgenic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17251190

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKL1105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17251190%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17251190%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

PubMed publication ID

17251190

1 reference