Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA (Q24291251)

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7 November 2019

title

Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA (English)

1 reference

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Methyl-CpG binding domain protein 1

7 November 2019

main subject

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double-stranded methylated DNA binding

GOA release 2020-03-11

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Methyl-CpG binding domain protein 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

1

1 reference

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7 November 2019

Takahisa Ikegami

5

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7 November 2019

author name string

N Shimotake

2

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7 November 2019

N Fujita

3

1 reference

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7 November 2019

J Jee

4

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7 November 2019

M Nakao

6

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7 November 2019

M Shirakawa

7

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7 November 2019

language of work or name

English

0 references

publication date

1 May 2001

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7 November 2019

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7 November 2019

volume

105

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7 November 2019

issue

4

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7 November 2019

page(s)

487-497

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A novel mode of DNA recognition by a beta-sheet revealed by the solution structure of the GCC-box binding domain in complex with DNA.

7 November 2019

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Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

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Methyl-CpG-binding proteins. Targeting specific gene repression.

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Effects of Rett syndrome mutations of the methyl-CpG binding domain of the transcriptional repressor MeCP2 on selectivity for association with methylated DNA

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Mammalian X-chromosome inactivation and the XIST gene

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Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

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Methylation-induced repression--belts, braces, and chromatin

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The methyl-CpG binding transcriptional repressor MeCP2 stably associates with nucleosomal DNA

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DNA hypomethylation leads to elevated mutation rates

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Major groove recognition by three-stranded beta-sheets: affinity determinants and conserved structural features

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Protein backbone angle restraints from searching a database for chemical shift and sequence homology

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Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

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A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins

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Rett syndrome: a surprising result of mutation in MECP2.

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DNA recognition by the methyl-CpG binding domain of MeCP2.

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Methylation-mediated transcriptional silencing in euchromatin by methyl-CpG binding protein MBD1 isoforms

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7 January 2021

Mechanism of transcriptional regulation by methyl-CpG binding protein MBD1

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7 January 2021

Asymmetric linker histone association directs the asymmetric rearrangement of core histone interactions in a positioned nucleosome containing a thyroid hormone response element

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7 January 2021

Identification and characterization of a family of mammalian methyl-CpG binding proteins

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7 January 2021

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

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7 January 2021

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

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7 January 2021

Protein-DNA interactions: A structural analysis

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AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

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7 January 2021

Linker DNA and H1-dependent reorganization of histone-DNA interactions within the nucleosome

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7 January 2021

Crystal structure of the nucleosome core particle at 2.8 A resolution

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7 January 2021

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

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7 January 2021

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

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7 January 2021

Active repression of methylated genes by the chromosomal protein MBD1

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7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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7 January 2021

Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1

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7 January 2021

The solution structure of a specific GAGA factor-DNA complex reveals a modular binding mode

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DNA methylation in health and disease

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Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region

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7 January 2021

Methyl-CpG-binding protein 2 mutations in Rett syndrome

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Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

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7 January 2021

The solution structure of the domain from MeCP2 that binds to methylated DNA

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NMR structure of the Tn916 integrase-DNA complex

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Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11371345%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017