Negative regulation of the deacetylase SIRT1 by DBC1 (Q24309090)

positive regulation of apoptotic process

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Wenhui Zhao

1

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Jan-Philipp Kruse

2

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Yi Tang

3

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Sung Yun Jung

4

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Jun Qin

5

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Wei Gu

The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases

6

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language of work or name

English

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publication date

31 January 2008

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published in

Nature

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volume

451

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issue

7178

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page(s)

587-90

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866287

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

19 March 2017

1 reference

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Caspase-dependent processing activates the proapoptotic activity of deleted in breast cancer-1 during tumor necrosis factor-alpha-mediated death signaling

19 March 2017

1 reference

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866287

Sirtuins: Sir2-related NAD-dependent protein deacetylases

19 March 2017

1 reference

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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866287

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

19 March 2017

1 reference

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DBC2, a candidate for a tumor suppressor gene involved in breast cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866287

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

19 March 2017

1 reference

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866287

Negative control of p53 by Sir2alpha promotes cell survival under stress

19 March 2017

1 reference

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Resveratrol improves health and survival of mice on a high-calorie diet

19 March 2017

1 reference

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Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

19 March 2017

1 reference

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

19 March 2017

1 reference

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Mechanism of human SIRT1 activation by resveratrol

19 March 2017

1 reference

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

19 March 2017

1 reference

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Substrate-specific activation of sirtuins by resveratrol

19 March 2017

1 reference

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Regulation of NF-kappaB action by reversible acetylation

19 March 2017

1 reference

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Mammalian SIRT1 represses forkhead transcription factors

19 March 2017

1 reference

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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

19 March 2017

1 reference

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Deacetylation of p53 modulates its effect on cell growth and apoptosis

19 March 2017

1 reference

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Therapeutic potential of resveratrol: the in vivo evidence

19 March 2017

1 reference

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Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

7 April 2017

1 reference

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Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes

7 April 2017

1 reference

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FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866287

Mutation analysis of the 8p candidate tumour suppressor genes DBC2 (RHOBTB2) and LZTS1 in bladder cancer

27 September 2017

1 reference

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Calorie restriction, SIRT1 and metabolism: understanding longevity

27 September 2017

1 reference

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Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors

27 September 2017

1 reference

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A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866287

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866287

29 November 2018

Identifiers

DOI

10.1038/NATURE06515

1 reference

Dimensions Publication ID

1042023669

0 references

Fatcat ID

release_6bcf5dkmqbhf5bjd5anjoekpca

0 references

1 reference

1 reference

PubMed publication ID

18235502

1 reference