Mechanism of 5'-directed excision in human mismatch repair (Q24300483)

GOA release 2020-03-11

DNA mismatch repair

1 reference

exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair

GOA release 2020-03-11

author name string

Jochen Genschel

series ordinal

1

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Paul Modrich

series ordinal

2

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language of work or name

English

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publication date

November 2003

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published in

Molecular Cell

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volume

12

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issue

5

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page(s)

1077-86

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cites work

1 reference

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7 January 2021

Nucleotide-promoted release of hMutSalpha from heteroduplex DNA is consistent with an ATP-dependent translocation mechanism

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7 January 2021

DNA chain length dependence of formation and dynamics of hMutSalpha.hMutLalpha.heteroduplex complexes

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7 January 2021

Mammalian DNA mismatch repair

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7 January 2021

Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex

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7 January 2021

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

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7 January 2021

Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line

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7 January 2021

MutS binding protects heteroduplex DNA from exonuclease digestion in vitro: a simple method for detecting mutations

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7 January 2021

Human exonuclease I is required for 5' and 3' mismatch repair

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7 January 2021

hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA

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7 January 2021

DNA mismatch repair and genetic instability

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7 January 2021

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

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7 January 2021

HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes

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7 January 2021

Eukaryotic mismatch repair: an update

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7 January 2021

Biochemistry and genetics of eukaryotic mismatch repair

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7 January 2021

Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs

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7 January 2021

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

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Mutation of a mutL homolog in hereditary colon cancer

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Partial reconstitution of human DNA mismatch repair in vitro: characterization of the role of human replication protein A

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Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis

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7 January 2021

The interaction of DNA mismatch repair proteins with human exonuclease I

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A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer

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7 January 2021

Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2

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7 January 2021

Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae

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7 January 2021

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

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7 January 2021

Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

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7 January 2021

Redundant exonuclease involvement in Escherichia coli methyl-directed mismatch repair

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7 January 2021

Mismatch repair in human nuclear extracts. Quantitative analyses of excision of nicked circular mismatched DNA substrates, constructed by a new technique employing synthetic oligonucleotides

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7 January 2021

Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility

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7 January 2021

Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1

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Germline mutations of EXO1 gene in patients with hereditary nonpolyposis colorectal cancer (HNPCC) and atypical HNPCC forms

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